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Bone Morphogenetic Proteins: Systems Biology Regulators, Slobodan Vukicevic; Kuber T. Sampath


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Автор: Slobodan Vukicevic; Kuber T. Sampath
Название:  Bone Morphogenetic Proteins: Systems Biology Regulators
ISBN: 9783319837536
Издательство: Springer
Классификация:




ISBN-10: 3319837532
Обложка/Формат: Soft cover
Страницы: 445
Вес: 0.94 кг.
Дата издания: 2017
Серия: Progress in Inflammation Research
Язык: English
Издание: Softcover reprint of
Иллюстрации: 32 illustrations, color; 11 illustrations, black and white; xii, 445 p. 43 illus., 32 illus. in color.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes. This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia.
Дополнительное описание: Introduction.- BMPs: Historic and Future Perspectives.- BMP – Biology.- BMPs in Development.- BMP signaling.- BMP Antagonists - Biology.- BMP and BMP Antagonists - Structure and Function.- BMPs in Orthopaedic Medicine: Promises and Challenges.- BMP6 and B



      Старое издание
Bone Morphogenetic Proteins: Systems Biology Regulators

Автор: Slobodan Vukicevic; Kuber Sampath
Название: Bone Morphogenetic Proteins: Systems Biology Regulators
ISBN: 3319475053 ISBN-13(EAN): 9783319475059
Издательство: Springer
Цена: 25155.00 р.
Наличие на складе: Есть у поставщикаПоставка под заказ.


Bone Morphogenetic Proteins: Systems Biology Regulators

Автор: Slobodan Vukicevic; Kuber Sampath
Название: Bone Morphogenetic Proteins: Systems Biology Regulators
ISBN: 3319475053 ISBN-13(EAN): 9783319475059
Издательство: Springer
Рейтинг:
Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Herbicide Resistance — Brassinosteroids, Gibberellins, Plant Growth Regulators

Автор: G. Adam; S.O. Duke; D. Gross; M. Lischewski; V. Ma
Название: Herbicide Resistance — Brassinosteroids, Gibberellins, Plant Growth Regulators
ISBN: 3642487890 ISBN-13(EAN): 9783642487897
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Chemistry of Plant Protection, Volume 7, provides critical review articles on new aspects of herbicide resis- tance, serving the needs of research scientists, pesticide manufacturers, government regulators, agricultural practitioners.

Bone Morphogenetic Proteins: Regeneration of Bone and Beyond

Автор: Slobodan Vukicevic; Kuber T. Sampath
Название: Bone Morphogenetic Proteins: Regeneration of Bone and Beyond
ISBN: 3034895984 ISBN-13(EAN): 9783034895989
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Since the discovery of the bone morphogenetic proteins (BMPs) more than 15 years ago, there has been an unpredicted explosion of both basic scientific discoveries and clinical reports on their use from institutions all over the world.

Bone Morphogenetic Proteins

Автор: Slobodan Vukicevic; Kuber T. Sampath
Название: Bone Morphogenetic Proteins
ISBN: 3034894465 ISBN-13(EAN): 9783034894463
Издательство: Springer
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Цена: 20896.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Morphogenetic Engineering

Автор: Ren? Doursat; Hiroki Sayama; Olivier Michel
Название: Morphogenetic Engineering
ISBN: 3662505649 ISBN-13(EAN): 9783662505649
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Generally, spontaneous pattern formation phenomena are random and repetitive, whereas elaborate devices are the deterministic product of human design. Yet, biological organisms and collective insect constructions are exceptional examples of complex systems that are both self-organized and architectural. This book is the first initiative of its kind toward establishing a new field of research, Morphogenetic Engineering, to explore the modeling and implementation of “self-architecturing” systems. Particular emphasis is placed on the programmability and computational abilities of self-organization, properties that are often underappreciated in complex systems science—while, conversely, the benefits of self-organization are often underappreciated in engineering methodologies. Altogether, the aim of this work is to provide a framework for and examples of a larger class of “self-architecturing” systems, while addressing fundamental questions such as > How do biological organisms carry out morphogenetic tasks so reliably? > Can we extrapolate their self-formation capabilities to engineered systems? > Can physical systems be endowed with information (or informational systems be embedded in physics) so as to create autonomous morphologies and functions? > What are the core principles and best practices for the design and engineering of such morphogenetic systems? The intended audience consists of researchers and graduate students who are working on, starting to work on, or interested in programmable self-organizing systems in a wide range of scientific fields, including computer science, robotics, bioengineering, control engineering, physics, theoretical biology, mathematics, and many others.

PAS Proteins: Regulators and Sensors of Development and Physiology

Автор: Stephen T. Crews
Название: PAS Proteins: Regulators and Sensors of Development and Physiology
ISBN: 1461351154 ISBN-13(EAN): 9781461351153
Издательство: Springer
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Цена: 13974.00 р.
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Описание:

The subject of this volume is a comprehensive examination of the biochemistry and biology of all classes of known PAS proteins, with the intention that readers will find insight into their own work and ideas from study of the multitude of PAS protein functions. PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.

Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders, and (6) mental health disorders such as social interactions and learning.

PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.

Bone Regulators and Osteoporosis Therapy

Автор: Stern Paula H.
Название: Bone Regulators and Osteoporosis Therapy
ISBN: 303057377X ISBN-13(EAN): 9783030573775
Издательство: Springer
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume is designed to provide an understanding of current and potential therapies for osteoporosis. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines.

Oncogenes as Transcriptional Regulators

Автор: Moshe Yaniv; Jacques Ghysdael
Название: Oncogenes as Transcriptional Regulators
ISBN: 3034898169 ISBN-13(EAN): 9783034898164
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes.

Oncogenes as Transcriptional Regulators

Автор: Moshe Yaniv; Jacques Ghysdael
Название: Oncogenes as Transcriptional Regulators
ISBN: 3034898339 ISBN-13(EAN): 9783034898331
Издательство: Springer
Рейтинг:
Цена: 6986.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes.

Extracellular ATP and adenosine as regulators of endothelial cell function

Автор: Evgenia Gerasimovskaya; Elzbieta Kaczmarek
Название: Extracellular ATP and adenosine as regulators of endothelial cell function
ISBN: 9400796803 ISBN-13(EAN): 9789400796805
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication.


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