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Applications Of Heterocycles In Drug Design,134, Meanwell, Nicholas A.


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Автор: Meanwell, Nicholas A.
Название:  Applications Of Heterocycles In Drug Design,134
ISBN: 9780128201817
Издательство: Elsevier Science
Классификация:

ISBN-10: 0128201819
Обложка/Формат: Hardcover
Страницы: 314
Вес: 0.61 кг.
Дата издания: 01.06.2021
Серия: Advances in heterocyclic chemistry
Язык: English
Размер: 22.86 x 15.24 x 1.91 cm
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Applications of Heterocycles in the Design of Drugs and Agricultural Products, Volume 134 in the Advances in Heterocyclic Chemistry series represents the most definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Chapters in this updated volume cover Hydroxy azoles as carboxylic acid bioisosteres, Cyclic sulfoxides and sulfones in drug design, Thiazoles and topological control in drug design, Applications of fused pyrrolidine [3.3.0] heterocycles in drug design, 1,4 Disubstituted and 1,4,5 trisubstituted-1,2,3-triazoles in drug discovery and development: from the flask to the clinic, and Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines.

Because biology and organic chemistry increasingly intersect, the associated nomenclature is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.




Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products

Автор: Albert Padwa
Название: Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products
ISBN: 0471387266 ISBN-13(EAN): 9780471387268
Издательство: Wiley
Цена: 44194.00 р.
Наличие на складе: Поставка под заказ.

Описание: A comprehensive reference on the synthetic chemistry of cycloaddition reactions Dipolar cycloaddion reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Such asymmetric syntheses have a growing importance in the pharmaceutical and agricultural industries with respect to the preparation of chiral drugs and natural products. This much-needed volume updates the popular 1984 edition with advances made over the last twenty years in cycloaddition reactions. While the 1984 volume focused on theory, structure, reactivities, and selectivities, the new volume is geared toward synthetic applications. Both carbonyl ylides and nitronates, important members of the 1,3-dipole family that were not reviewed previously, are now included. Also, beyond the capability of the 1,3-dipolar cycloadditon reaction to produce heterocycles, the ability of heteroatom-containing cycloadducts to transform into a variety of other functionalized organic molecules, cylclic or acyclic, and the ability of many 1,3-dipolar cycloadditions to generate rings containing several contiguous stereocenters in one synthetic operation is discussed. Volume 59 provides the only comprehensive reference on the market detailing the synthetic chemistry of cycloaddition reactions.

Synthesis of Saturated Oxygenated Heterocycles II

Автор: Janine Cossy
Название: Synthesis of Saturated Oxygenated Heterocycles II
ISBN: 3662525143 ISBN-13(EAN): 9783662525142
Издательство: Springer
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Цена: 28732.00 р.
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Описание: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community.

Synthesis of Heterocycles via Cycloadditions I

Автор: Alfred Hassner
Название: Synthesis of Heterocycles via Cycloadditions I
ISBN: 3642097081 ISBN-13(EAN): 9783642097089
Издательство: Springer
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Цена: 44582.00 р.
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Описание: Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature. This series covers hot topics of frontier research summarized by reputed scientists in the field.

Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles

Автор: Yoon Hyung
Название: Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles
ISBN: 3030540766 ISBN-13(EAN): 9783030540760
Издательство: Springer
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Цена: 20962.00 р.
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Описание: In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination.

The Chemistry of Heterocycles: Structure, Reactions, Synthesis, and Applications

Автор: Eicher
Название: The Chemistry of Heterocycles: Structure, Reactions, Synthesis, and Applications
ISBN: 3527327479 ISBN-13(EAN): 9783527327478
Издательство: Wiley
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Цена: 11563.00 р.
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Описание: * Clearly structured with proven systematic: The ordering system according to the ring size of the heterocycles will remain. * New: The contents of the important chapter "Problems and their Solutions" will be completely re-structured and enhanced with up-to-date scientific exercises. A great tool for self-testing and exams.

Heterocycles: Synthesis, Reactions and Applications

Автор: Jonas M. Danielsen
Название: Heterocycles: Synthesis, Reactions and Applications
ISBN: 1536178047 ISBN-13(EAN): 9781536178043
Издательство: Nova Science
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Цена: 22491.00 р.
Наличие на складе: Невозможна поставка.

Описание: Considering the extensive applications that have been discovered for naphthoquinone-triazole hybrids in the search for new bioactive molecules, Heterocycles: Synthesis, Reactions and Applications first comprehensively addresses recent synthetic strategies for their preparation. The authors highlight recent developments in reaction strategies for the synthesis of dihydro-, tetrahydro-, pyrano-pyrans and tetrahydrofurans and their applications in natural product synthesis. The important structural features of heterocyclic compounds are reviewed, as well as their deviation from the planar configuration in the form of puckering or buckling, and methods of suppression. The closing study explores the reaction of azides with Grignard or organolithium reagents in an inter- or intramolecular fashion to form linear or cyclic triazene intermediates, respectively.

Green synthetic approaches for biologically relevant heterocycles

Название: Green synthetic approaches for biologically relevant heterocycles
ISBN: 0128205865 ISBN-13(EAN): 9780128205860
Издательство: Elsevier Science
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Цена: 33686.00 р.
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Описание:

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions.

This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.

Green synthetic approaches for biologically relevant heterocycles

Название: Green synthetic approaches for biologically relevant heterocycles
ISBN: 0128207922 ISBN-13(EAN): 9780128207925
Издательство: Elsevier Science
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Цена: 33686.00 р.
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Описание:

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids.

This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.

?-Aminoacid-N-Carboxy-Anhydrides and Related Heterocycles

Автор: Hans R. Kricheldorf
Название: ?-Aminoacid-N-Carboxy-Anhydrides and Related Heterocycles
ISBN: 3642715885 ISBN-13(EAN): 9783642715884
Издательство: Springer
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Цена: 14365.00 р.
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Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-Coupling Reactions

Автор: Patonay Tamбs, Kуnya Krisztina
Название: Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-Coupling Reactions
ISBN: 3319813277 ISBN-13(EAN): 9783319813271
Издательство: Springer
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Цена: 27950.00 р.
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Описание: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community.

Phosphorous Heterocycles I

Автор: Raj K. Bansal
Название: Phosphorous Heterocycles I
ISBN: 3642101445 ISBN-13(EAN): 9783642101441
Издательство: Springer
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Цена: 59955.00 р.
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Описание: Raj K. Bansal: Anellated Azaphospholes.- Barbara Lejczak, Pawel Kafarski: Biological Activity of Aminophosphonic Acids and Their Short Peptides.- Gyцrgy Keglevich: Phosphinine Derivatives and their Use as Versatile Intermediates in P-Heterocyclic Chemistry.- K.C. Kumara Swamy, M. Phani Pavan, Venu Srinivas: Spiro- and Tricyclic Phosphoranes with Six- and Higher-Membered Rings.- Pascal Le Floch: The Chemistry of Phosphinines.- Sergey Cherenok, Vitaly Kalchenko: Phosphorus-Containing Calixarenes.- Anne-Marie Caminade, Jean-Pierre Majoral: From Phosphorus-Containing Macrocycles to Phosphorus-Containing Dendrimers.-

Synthesis of 4- to 7-membered Heterocycles by Ring Expansion

Автор: Matthias D`hooghe; Hyun-Joon Ha
Название: Synthesis of 4- to 7-membered Heterocycles by Ring Expansion
ISBN: 3319797085 ISBN-13(EAN): 9783319797083
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community.


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