Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Автор: Cheng Zhen Название: Fluorescent Imaging in Medicinal Chemistry ISBN: 3030467066 ISBN-13(EAN): 9783030467067 Издательство: Springer Рейтинг: Цена: 53106.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the most recent developments of fluorescent imaging techniques for medicinal chemistry research and biomedical applications, including cell imaging, in vitro diagnosis and in vivo imaging. Fluorescent imaging techniques play an important role in basic research, drug discovery and clinical translation.
Автор: Sabnis Название: Handbook of Fluorescent Dyes and Probes ISBN: 1118028694 ISBN-13(EAN): 9781118028698 Издательство: Wiley Рейтинг: Цена: 23118.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A COMPLETE, UP-TO-DATE RESOURCE OF INFORMATION ON MORE THAN 150 FLUORESCENT DYES AND PROBES Handbook of Fluorescent Dyes and Probes is the most comprehensive volume available on the subject, covering all the available dyes and probes known to date in the literature for uses in various fields. Top dye expert Dr.
Автор: Xu Jiarui, Chi Zhenguo, Schneider Hans-Jorg Название: Mechanochromic Fluorescent Materials: Phenomena, Materials and Applications ISBN: 1849738211 ISBN-13(EAN): 9781849738217 Издательство: Royal Society of Chemistry Рейтинг: Цена: 32736.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction to the concept of mechanofluorochromism and the variety of applications of this group of materials.
Автор: Kaur Название: Fluorescent Tools for Imaging Oxidative Stress in Biology ISBN: 3319734040 ISBN-13(EAN): 9783319734040 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction.- Flavin based redox probes.- FRET based ratiometric redox probes.- Mitochondrially-targeted ratiometric redox probes.- Nicotinamide based ratiometric probes.- In cellulo studies.- Ex vivo studies.- Non-mammalian systems.- Conclusions.- Experimental Methods.
Автор: Robert Hoffman Название: In Vivo Cellular Imaging Using Fluorescent Proteins ISBN: 1493961497 ISBN-13(EAN): 9781493961498 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book ranges from the employment of the chick CAM model using fluorescent proteins and other fluorescent probes to intravital fluorescent imaging, 3-dimensional imaging and making new far-red and infrared fluorescent proteins.
Автор: Amandeep Kaur Название: Fluorescent Tools for Imaging Oxidative Stress in Biology ISBN: 3030103714 ISBN-13(EAN): 9783030103712 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This thesis advances the long-standing challenge of measuring oxidative stress and deciphering its underlying mechanisms, and also outlines the advantages and limitations of existing design strategies. It presents a range of approaches for the chemical synthesis of fluorescent probes that detect reversible changes in cellular oxidative stress. The ability to visualise cellular processes in real-time is crucial to understanding disease development and streamline treatment, and this can be achieved using fluorescent tools that can sense reversible disturbances in cellular environments during pathogenesis. The perturbations in cellular redox state are of particular current interest in medical research, since oxidative stress is implicated in the pathogenesis of a number of diseases.The book investigates different strategies used to achieve ratiometric fluorescence output of the reversible redox probes, which nullify concentration effects associated with intensity-based probes. It also describes suitable approaches to target these probes to specific cellular organelles, thereby enabling medical researchers to visualise sub-cellular oxidative stress levels, and addressing the typically poor uptake of chemical tools into biological studies. In total it reports on four new probes that are now being used by over twenty research groups around the globe, and two of which have been commercialised. The final chapters of this thesis demonstrate successful applications of the sensors in a variety of biological systems ranging from prokaryotes to mammalian cells and whole organisms. The results described clearly indicate the immense value of collaborative, cross-disciplinary research.
Автор: Hicks Название: Green Fluorescent Proteins + CD ISBN: 0896039056 ISBN-13(EAN): 9780896039056 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Barry W. Hicks and a team of well-practiced experimentalists demonstrate the power and the versatility of the green fluorescent protein (GFP) marker with a cutting-edge collection of readily reproducible GFP techniques. These include methods for detecting and imaging GFP (FRET, BRET, and whole-body imaging); for using GFP to create and select for transgenic organisms, for its use as a biosensor; and for studying viruses. A valuable companion CD-ROM displays many color figures and videos from over half the chapters.
Название: The Fluorescent Protein Revolution ISBN: 0367378701 ISBN-13(EAN): 9780367378707 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Нет в наличии.
Описание:
Advances in fluorescent proteins, live-cell imaging, and superresolution instrumentation have ushered in a new era of investigations in cell biology, medicine, and physiology. From the identification of the green fluorescent protein in the jellyfish Aequorea victoria to the engineering of novel fluorescent proteins, The Fluorescent Protein Revolution explores the history, properties, and applications of these important probes.
The book first traces the history of fluorescent proteins and the revolution they enabled in cellular imaging. It then discusses fluorescent proteins with novel photophysical properties. The book also covers several cutting-edge imaging applications. These include superresolution microscopy of cellular fine structures, FRET microscopy to visualize protein interactions and cell-signaling activities inside living cells, photobleaching and photoactivation techniques to visualize protein behaviors, techniques that exploit plant and algal photoreceptors to enable light-regulated control of enzymatic activities, and the noninvasive imaging of tumor-host interactions in living animals.
In color throughout, this book presents the fundamental principles and latest advances in the field, including the associated development of imaging techniques that exploit fluorescent proteins. It is accessible to a broad audience, from optical imaging experts to novices needing an introduction to the field.
Автор: Wu Fu-Gen Название: Fluorescent Materials for Cell Imaging ISBN: 9811550611 ISBN-13(EAN): 9789811550614 Издательство: Springer Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents recently developed fluorescent materials, including semiconductor quantum dots, carbon dots, silicon nanoparticles, metal nanoclusters, upconversion nanoparticles, conjugated polymers/polymer dots, aggregation-induced emission (AIE) probes, and coordination compounds, used for various cellular imaging purposes.
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