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Current Advances in the Science of Osteosarcoma: Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and, Kleinerman Eugenie S., Gorlick Richard


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Автор: Kleinerman Eugenie S., Gorlick Richard
Название:  Current Advances in the Science of Osteosarcoma: Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and
ISBN: 9783030430870
Издательство: Springer
Классификация:



ISBN-10: 3030430871
Обложка/Формат: Paperback
Страницы: 233
Вес: 0.44 кг.
Дата издания: 22.08.2021
Язык: English
Размер: 25.40 x 17.81 x 1.32 cm
Ссылка на Издательство: Link
Поставляется из: Германии
Описание:

This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.




Current Advances in the Science of Osteosarcoma: Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and

Автор: Kleinerman Eugenie S., Gorlick Richard
Название: Current Advances in the Science of Osteosarcoma: Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and
ISBN: 3030430847 ISBN-13(EAN): 9783030430849
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

1 The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies

2 Genomics and the Immune Landscape of Osteosarcoma

3 RECQ DNA Helicases and Osteosarcoma

4 Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma

5 Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma

6 Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response

7 Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma

8 Wnt Signaling in Osteosarcoma

9 Receptor Tyrosine Kinases in Osteosarcoma: 2019 update

10 The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets

11 Autophagy in OS

12 Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs

13 Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment

14 Comparative Immunology and Immunotherapy of Canine Osteosarcoma

Index
Current Advances in Osteosarcoma: Clinical Perspectives: Past, Present and Future

Автор: Kleinerman Eugenie S., Gorlick Richard
Название: Current Advances in Osteosarcoma: Clinical Perspectives: Past, Present and Future
ISBN: 3030430316 ISBN-13(EAN): 9783030430313
Издательство: Springer
Рейтинг:
Цена: 22359.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This thoroughly revised second edition complied in 2 books is an up-to-date overview of the current clinical advances in sarcoma and osteosarcoma.

Current Advances in Osteosarcoma

Автор: Eugenie S. Kleinerman, M.D.
Название: Current Advances in Osteosarcoma
ISBN: 3319344595 ISBN-13(EAN): 9783319344591
Издательство: Springer
Рейтинг:
Цена: 18284.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Current Advances in Osteosarcoma edited by Dr. Eugenie S. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma.

Tumor Microenvironment: Recent Advances

Автор: Birbrair Alexander
Название: Tumor Microenvironment: Recent Advances
ISBN: 3030357295 ISBN-13(EAN): 9783030357290
Издательство: Springer
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: 1. Novel techniques to study the bone-tumor microenvironment2. An emerging model for cancer development from a tumor microenvironment perspective in mice and humans3. Effects of Exercise on the Tumour Microenvironment4. Effects of inhaled tobacco smoke on the pulmonary tumor microenvironment5. Multimodal molecular imaging of the tumour microenvironment6. Necrosis in the tumor microenvironment and its role in cancer recurrence7. The Multifaceted Effects of Autophagy on the Tumor Microenvironment8. The Sociobiology of Brain Tumors9. Tumor microenvironment conditioning by abortive lytic replication of oncogenic γ-herpesviruses10. The microbiome as a component of the tumor microenvironmentIndex

Systems Biology of Tumor Microenvironment

Автор: Rejniak
Название: Systems Biology of Tumor Microenvironment
ISBN: 3319420216 ISBN-13(EAN): 9783319420219
Издательство: Springer
Рейтинг:
Цена: 22203.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microenvironmental barriers in oxygen and drug delivery to tumors, the development of tumor microenvironmental niches and sanctuaries, intravenous transport of the circulating tumor cells, the role of the tumor microenvironment in chemotherapeutic interventions, the interactions between tumor cells, the extracellular matrix, the interstitial fluid, and the immune and stromal cells. Mathematical models discussed here embrace both continuous and agent-based approaches, as well as mathematical frameworks of solid mechanics, fluid dynamics and optimal control theory. The topics in each chapter will be of interest to a biological community wishing to apply the mathematical methods to interpret their experimental data, and to a biomathematical audience interested in exploring how mathematical models can be used to address complex questions in cancer biology.

Breast Cancer: Tumor Microenvironment and Biology

Автор: Lekin Sandra
Название: Breast Cancer: Tumor Microenvironment and Biology
ISBN: 1632410680 ISBN-13(EAN): 9781632410689
Издательство: Неизвестно
Цена: 20108.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The causes of cancer are diversified. Cancer is the principal reason of death in the majority of countries and it results in enormous financial, societal and mental burden. Breast cancer is the most diagnosed kind of cancer and the foremost reason of deat

Current Advances in Osteosarcoma: Clinical Perspectives: Past, Present and Future

Автор: Kleinerman Eugenie S., Gorlick Richard
Название: Current Advances in Osteosarcoma: Clinical Perspectives: Past, Present and Future
ISBN: 3030430340 ISBN-13(EAN): 9783030430344
Издательство: Springer
Цена: 22359.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This thoroughly revised second edition complied in 2 books is an up-to-date overview of the current clinical advances in sarcoma and osteosarcoma.

Tumor Microenvironment: Recent Advances

Автор: Birbrair Alexander
Название: Tumor Microenvironment: Recent Advances
ISBN: 3030357260 ISBN-13(EAN): 9783030357269
Издательство: Springer
Рейтинг:
Цена: 22359.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: 1. Novel techniques to study the bone-tumor microenvironment2. An emerging model for cancer development from a tumor microenvironment perspective in mice and humans3. Effects of Exercise on the Tumour Microenvironment4. Effects of inhaled tobacco smoke on the pulmonary tumor microenvironment5. Multimodal molecular imaging of the tumour microenvironment6. Necrosis in the tumor microenvironment and its role in cancer recurrence7. The Multifaceted Effects of Autophagy on the Tumor Microenvironment8. The Sociobiology of Brain Tumors9. Tumor microenvironment conditioning by abortive lytic replication of oncogenic γ-herpesviruses10. The microbiome as a component of the tumor microenvironmentIndex

Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy

Автор: Pawel Kalinski
Название: Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy
ISBN: 3319884506 ISBN-13(EAN): 9783319884509
Издательство: Springer
Рейтинг:
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics.


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