Sarcopenia: Research and Clinical Implications, Veronese Nicola, Beaudart Charlotte, Sabico Shaun
Автор: Gordon S. Lynch Название: Sarcopenia – Age-Related Muscle Wasting and Weakness ISBN: 9400790449 ISBN-13(EAN): 9789400790445 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Some of the most serious consequences of aging are its effects on skeletal muscle. This book provides the latest state-of-the-art information on sarcopenia. It includes contributions from some of the world`s leading experts in skeletal muscle aging.
Автор: Matsumoto Rae R., Bowen Wayne D., Su Tsung-Ping Название: Sigma Receptors / Chemistry, Cell Biology and Clinical Implications ISBN: 0387365125 ISBN-13(EAN): 9780387365121 Издательство: Springer Рейтинг: Цена: 33401.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an update on sigma receptors, and summarizes recent advances in the medicinal chemistry, molecular biology, and cell biology of sigma receptors. It describes the functional effects mediated by these receptors and the potential clinical implications of these actions. This information is put in a historical perspective to help newcomers to the field successfully navigate the confusing early history surrounding these proteins, and provides a launching point from which future studies and research directions can easily be developed. Major advances in our understanding of sigma receptors have been made during the past few years. This book will facilitate exciting new research that could lead to significant advances in the treatment of neurologic, psychiatric, cardiovascular, immunologic, and gastrointestinal disorders through a better understanding of sigma receptors.
Автор: Kato Название: Recent Advances of Sarcopenia and Frailty in CKD ISBN: 9811523649 ISBN-13(EAN): 9789811523649 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights recent advances in our understanding of sarcopenia and frailty in CKD.
Описание: The increasingly widespread implementation and use of intelligent assistive technologies (IATs) is reshaping dementia care. This volume provides an up-to-date overview of the current state of IATs for dementia care. The new essays collected here examine what IATs will mean for clinical practice and the ethical and regulatory challenges they will pose.
Автор: Mario D. Cordero; El?sabet Alcocer-G?mez Название: Inflammasomes: Clinical and Therapeutic Implications ISBN: 3030077586 ISBN-13(EAN): 9783030077587 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The inflammasome is a protein complex composed of an intracellular sensor—typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1? and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1? has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic options. This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect. There is a need for re-establishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated.
Автор: Mendelsohn Andrew R., Larrick James W. Название: Medical Implications of Basic Research in Aging Volume 2 ISBN: 0991216229 ISBN-13(EAN): 9780991216222 Издательство: Неизвестно Цена: 7644.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Medical Implications of Basic Research in Aging Volume 2 provides an updated sampling through 2017 of the most important discoveries of the past several years relevant to aging research in the context of enhancing life- and healthspan. Have you ever wondered if there is anything that you can do to slow aging or prevent diseases associated with aging? Are you interested in enhancing your health based on the latest scientific discoveries? Are you a biohacker experimenting on your own body in an attempt to live longer? Assembled in this volume are a number of the commentaries that previously appeared in the scientific journal Rejuvenation Research. The presentations are clearly written and accessible to those with a general background in biology and medical science. An overview summarizes the articles for the educated layman. Thorough referencing provides an opportunity for further in-depth reading.
Автор: Kato N., Kawata M., Pitman R. K. Название: Ptsd: Brain Mechanisms and Clinical Implications ISBN: 4431560874 ISBN-13(EAN): 9784431560876 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent catastrophic events, such as the attack on the New York World Trade Center and the devastating tsunami in the Indian Ocean, have drawn increasing attention to post-traumatic stress disorder, or PTSD. Once thought of only in psychological terms, PTSD has emerged as the model mental disorder for studying the effect of the environment on human biological systems, especially the brain. This book breaks new ground by offering neuroscientific insights into PTSD and their implications for diagnosis, prevention, and treatment. The recent explosion of biological investigation into this distressing and disabling condition has been led by this volume’s authors, who range from skilled basic scientists to experienced diagnosticians and therapists. Their contributions epitomize state-of-the-art, translational research in clinical neuroscience, and will prove to be an invaluable source of reference for practitioners and researchers in this field.
Автор: Cordero Название: Inflammasomes: Clinical and Therapeutic Implications ISBN: 3319893890 ISBN-13(EAN): 9783319893891 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The inflammasome is a protein complex composed of an intracellular sensor—typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1? and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1? has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic options. This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect. There is a need for re-establishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated.
Автор: Nikolaos Labrou Название: Therapeutic Enzymes: Function and Clinical Implications ISBN: 9811377081 ISBN-13(EAN): 9789811377082 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Поставка под заказ.
Описание: Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
