An essential introduction to microbiome science, a new cutting-edge discipline that is transforming the life sciences
This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. Resident microbes in healthy animals--including humans-can dictate many traits of the animal host. This animal microbiome is a second immune system conferring protection against pathogens; it can structure host metabolism in animals as diverse as reef corals and hibernating mammals; and it may influence animal behavior, from social recognition to emotional states. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet, and have contributed to animal diversification over long evolutionary timescales. Drawing on concepts and data across a broad range of disciplines and systems, Angela Douglas provides a conceptual framework for understanding these animal-microbe interactions while shedding critical light on the scientific challenges that lie ahead. Douglas explains why microbiome science demands creative and interdisciplinary thinking-the capacity to combine microbiology with animal physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science. An essential introduction to a cutting-edge field that is revolutionizing the life sciences, this book explains why microbiome science presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for many medical conditions and new strategies for pest control.
Автор: Jia, Huijue (director, Shenzhen Key Laboratory Of Human Commensal Microorganisms And Health Research, Bgi-shenzhen; Mentor For Graduate Students, Bgi Название: Investigating human diseases with the microbiome ISBN: 0323913695 ISBN-13(EAN): 9780323913690 Издательство: Elsevier Science Рейтинг: Цена: 21391.00 р. Наличие на складе: Поставка под заказ.
Описание: Thoroughly written, extensively updated, and optimized for today`s evolving Canadian healthcare environment,Psychiatric & Mental Health Nursing for Canadian Practice,5th Edition, equips students with the fundamental knowledge and skills to effectively care for diverse populations in psychiatric and mental health nursing practice. This proven, approachable text instills a generalist-level mastery of psychiatric and mental health promotion, assessment, and interventions in adults, families, children, adolescents, and older adults, delivering Canadian students the preparation they need to excel on the NCLEX(R) exam and make a confident transition to clinical practice.
Автор: Gupta Название: Microbiome in Inflammatory Lung Diseases ISBN: 9811689563 ISBN-13(EAN): 9789811689567 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Поставка под заказ.
Описание: This book reviews the role of the lung microbiome in the development and progression of lung diseases. It deals with the role of microbiota dysbiosis in influencing host defense and immunity leading to resistance, colonization, and disease exacerbation. The book delineates the complex interaction between pathogen and lung residual microbiota during disease conditions. It further highlights the potential role of lung microbiota as the key modulator of lung carcinogenesis and immune response against cancer cells. Lastly, it reviews technological developments for unraveling the lung microbiome that profoundly impacts clinical diagnostics. This book is an essential resource for the scientists working in pulmonary diseases, pharmaceutical & clinical sciences, and pulmonary clinicians.
Автор: Kumar Ajay, Singh Joginder, Ferreira Luiz Fernando Romanholo Название: Microbiome Under Changing Climate: Implications and Solutions ISBN: 0323905714 ISBN-13(EAN): 9780323905718 Издательство: Elsevier Science Рейтинг: Цена: 29476.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Microbiome Under Changing Climate: Implications and Solutions presents the latest biotechnological interventions for the judicious use of microbes to ensure optimal agricultural yield. Summarizing aspects of vulnerability, adaptation and amelioration of climate impact, this book provides an important resource for understanding microbes, plants and soil in pursuit of sustainable agriculture and improved food security. It emphasizes the interaction between climate and soil microbes and their potential role in promoting advanced sustainable agricultural solutions, focusing on current research designed to use beneficial microbes such as plant growth promoting microorganisms, fungi, endophytic microbes, and more.
Changes in climatic conditions influence all factors of the agricultural ecosystem, including adversely impacting yield both in terms of quantity and nutritional quality. In order to develop resilience against climatic changes, it is increasingly important to understand the effect on the native micro-flora, including the distribution of methanogens and methanotrophs, nutrient content and microbial biomass, among others.
Автор: Yinglin Xia; Jun Sun; Ding-Geng Chen Название: Statistical Analysis of Microbiome Data with R ISBN: 9811346453 ISBN-13(EAN): 9789811346453 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Поставка под заказ.
Описание: This unique book addresses the statistical modelling and analysis of microbiome data using cutting-edge R software. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of R for data analysis step by step. The data and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter, so that these new methods can be readily applied in their own research. The book also discusses recent developments in statistical modelling and data analysis in microbiome research, as well as the latest advances in next-generation sequencing and big data in methodological development and applications. This timely book will greatly benefit all readers involved in microbiome, ecology and microarray data analyses, as well as other fields of research.
Автор: Beiko Название: Microbiome Analysis ISBN: 1493987267 ISBN-13(EAN): 9781493987269 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume aims to capture the entire microbiome analysis pipeline, sample collection, quality assurance, and computational analysis of the resulting data. Chapters detail several example applications of microbiome research, and the protocols described in this book are complemented with short perspectives about the history, current state, and future directions of protocols in microbiomics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Microbiome Analysis: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Автор: Floch, Martin H. Название: Colorectal Neoplasia And The Colorectal Microbiome ISBN: 0128196726 ISBN-13(EAN): 9780128196724 Издательство: Elsevier Science Рейтинг: Цена: 22738.00 р. Наличие на складе: Поставка под заказ.
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Colorectal Neoplasia and the Microbiome: Dysplasia, Probiotics, and Fusobacteria provides foundational knowledge on the gut microbiome and evidence for an association with colorectal neoplasia. It covers the role of microbiota in causing adenomatous polyps and colorectal cancer as well as the modulatory effect of diet and probiotics. Chapters explain a foundational history of microbiology in the colon, the epidemiology of colon polyps and cancer, dysbiosis, the role of immunology and bacteria, and the diet. The book combines medical and scientific aspects to show mechanistic aspects between microbiota and hosts, clearly presenting the association between microbiota, colonic lesions and possible causal links.
The book is essential reading for everyone working with human microbiota including basic scientists, physiologists of the intestine, experts in intestinal microbiota, gastroenterologists, oncologists and surgeon.
Автор: Sharon Lafferty Doty Название: Functional Importance of the Plant Microbiome ISBN: 3319658964 ISBN-13(EAN): 9783319658964 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book addresses all the major mechanisms by which endophytes are thought to impact plant growth and health. A unique aspect of this publication is that it is multidisciplinary, covering plant microbiology, plant physiology, fungal and bacterial endophytes, plant biochemistry, and genomics.
Just as research on the mammalian microbiome has demonstrated its importance for overall health of the host, the plant microbiota is essential for plant health in natural environments. Endophytes, the microorganisms living fully within plants, can provide a multitude of benefits to the host including N-fixation, P solubilization, increased photosynthetic efficiency and water use efficiency, stress tolerance, pathogen resistance, and overall increased growth and health. A variety of culturable endophytes have been isolated and shown to be mutualistic symbionts with a broad range of plant species. These studies point to the functional importance of the microbiota of plants and suggest the potential for tailoring plant microbiota for improved vigor and yields with reduced inputs. This review covers the major benefits of microbial endophytes to plants and discusses the implications of using symbiosis as an alternative to chemical inputs for agriculture, forestry, and bioenergy.
Автор: Claud, Erika Chiong Название: The Developing Microbiome ISBN: 0128206020 ISBN-13(EAN): 9780128206027 Издательство: Elsevier Science Рейтинг: Цена: 21728.00 р. Наличие на складе: Поставка под заказ.
Описание:
The Developing Microbiome: Lessons from Early Life focuses on the establishment of the microbiome in early life, exposing it as a key mediator of diseases and health throughout the lifecycle. The content presents a comprehensive view of the status of the field and draws real-world correlations to health and disease states. It collates the significant research being done in the pediatric microbiome research space and bridges the knowledge gap showing the factors that impact health and disease states throughout the lifecycle. Finally, it offers knowledge on how the microbiome is and can be manipulated to promote change.
This is a perfect reference for both researchers and clinical scientists who are interested in the role of the infant microbiome in health and disease, as well as gastroenterologists and pediatricians looking to affect change in their patients.
Автор: Xia Yinglin, Sun Jun, Chen Ding-Geng Название: Statistical Analysis of Microbiome Data with R ISBN: 9811315337 ISBN-13(EAN): 9789811315336 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chapter 1: Introduction to R, RStudio and ggplot2 1.1 Introduction to R 1.2 Introduction to RStudio 1.3 Introduction to ggplot2 1.4 Introduction to R Packages for Microbiome Data Chapter 2: What are Microbiome Data?2.1 Phylogenetics--The Basics 2.2 What Microbiome Data Look Like? 2.2.1 Basic Data Structure and Format of Microbiome Data 2.2.2 OUT Table2.2 3 Response Variables and Covariates2.3 Some Specific Features of Microbiome Data Chapter 3: Bioinformatic and Statistical Analyses of Microbiome Data 3.1 Overview of Bioinformatic Analysis 3.1.1 Taxonomic Diversity: from the 16S-based Approach 3.1.2 Taxonomic Profiling of Shotgun Metagenomes3.1.3 Introduction to Bioinformatic toolso QIIME o Mothuro 16S rRNA Gene Sequence Data Analysis using QIIME and Mothuro Other Biostatistics Tools3.2 Statistical Analysis of Microbiome Community Composition 3.2.1 Alpha Diversity Analysis and Statistical Measurements 3.2.2 Beta Diversity Analysis and Statistical Measurements3.3 Multivariate Statistical Techniques 3.3.1Data Visualization: Principal Component and Principal Coordinates Analyses 3.3.2 Classification and Clustering with Visualization 3.4 Hypothesis Testing and Statistical Modeling 3.4.1 Statistical Testing of Microbiome Community 3.4.2 Multivariate Statistical Methods and Modeling of Microbiome Community and Environmental Covariates3.4.3 Mediational and Longitudinal Microbiome Data Analysis3.4.4 Host Interactions and Interventions3.4.5 Mediation Analysis and Longitudinal Analysis 3.5 Multiple Comparisons and Testing Correlation 3.6 Correlation Analysis of Microbiome Community and Environmental Covariates Chapter 4: Power and Sample Size Calculation in Hypothesis Testing Microbiome Data4.1 Statistical Hypothesis Testing and Power Analysis 4.1.1 Hypothesis Testing 4.1.2 Power Analysis and Sample Size Calculation4.2 Comparing Diversity or a Taxon of Interest between Two Groups 4.2.1 Hypotheses and Basic Power and Sample Size Formulas4.2.2 Diversity Data for Vitamin D and Vitamin D Receptor Study4.2.3 Theory of Power for a Test for Comparing Proportions4.2.4 Power of Fisher's Exact Test for Comparing Proportions4.2.5 R Function power.t.test4.3 Comparing Diversity across More than Two Groups 4.3.1 Hypotheses and Theory of Power for One-Way ANOVA4.3.2 Examples4.3.2 R Function pwr.avova.test4.4 Comparing the Frequency of all Taxa across Groups4.4.1 Hypotheses Testing and Power and Sample Size Calculations for Comparing all Taxa4.4.2 Dirichlet-multinomial model in Power and Sample Size Analyses4.4.3 Power and Size Calculations using HMP Package4.5 Power and Sample Size Estimation using Pairwise Distances and PERMANOVA 4.5.1 PERMANOVA and Estimation of PERMANOVA Power 4.5.2 Examples using micropower Package4.6 Power Calculations using ANOSIM Package Chapter 5: Microbiome Data Management5.1 Data Importing and Merging datasets or components 5.1.1 Importing the Output from QIIME 5.1.2 Importing the Output from mothur&
Автор: Victor Pylro; Luiz Roesch Название: The Brazilian Microbiome ISBN: 3319867555 ISBN-13(EAN): 9783319867557 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: Brazilian Microbiome: Current status and perspectives unites a set of distinguished investigators conducting microbiome research and builds a comprehensive reference book with up-to-date information regarding the Brazilian microbiome studies and trends.
Автор: Ravindra Pal Singh; Ramesh Kothari; Prakash G. Kor Название: Understanding Host-Microbiome Interactions - An Omics Approach ISBN: 9811353042 ISBN-13(EAN): 9789811353048 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Поставка под заказ.
Описание: This book offers up-to-date information on different microbiomes, their community composition and interactive functions with the host, bringing together information from diverse research reports to provide an overview of the rapid developments in meta-omics technologies. It is a valuable resource for scientists, researchers, postgraduate and graduate students interested in understanding the impact and importance of next generation sequencing technologies on different hosts and their microbiomes.
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