Redox Signaling and Biomarkers in Ageing, Зakatay Ufuk
Автор: Viktor Magdolen, Christian P. Sommerhoff, Hans Fritz, Manfred Schmitt Название: Novel cancer-related biomarkers ISBN: 3110303582 ISBN-13(EAN): 9783110303582 Издательство: Walter de Gruyter Цена: 26024.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Various KLK proteins and their encoding genes have attracted increased attention among scientists and clinicians worldwide since they represent very interesting and functionally distinct biomarkers, particularly, in cancer. This book reviews the role of kallikrein-related peptidases (KLKs) in a wide range of cancers, including lung, prostate, breast and ovarian cancer. It provides clinicians, physician scientists and researchers with a comprehensive overview on the clinical relevance of KLK expression in various malignancies.
Автор: Alexey Moskalev Название: Biomarkers of Human Aging ISBN: 3030249697 ISBN-13(EAN): 9783030249694 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging.In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function).The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging.Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.
Автор: Manuel Men?ndez Gonz?lez Название: Atlas of Biomarkers for Alzheimer`s Disease ISBN: 3319079883 ISBN-13(EAN): 9783319079882 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A lot of research on biomarkers for Alzheimer is being done in the last few decades. The aim of these studies is to find some method to ease the diagnosis of Alzheimers as early as possible. Such methods are a range of blood or CSF tests on one hand and several types of neuroimaging scans on the other. Many of the images coming both from laboratory and neuroimaging are very visual and illustrative. These images, accompanied by a short description, can perfectly explain the main results and usefulness of every biomarker. The objective of this book would be to summarize the most important studies made in this field. Few publications have systematically compiled results on this topic and only one as an atlas. Readers would be interested in this publication because it allows reviewing the current status of research by handily visualizing the results.
Автор: Armstrong Donald Название: Oxidative Stress Biomarkers and Antioxidant Protocols ISBN: 0896038505 ISBN-13(EAN): 9780896038509 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Donald Armstrong updates and expands his highly praised Free Radical and Antioxidant Protocols (Humana, 1998) with a collection of new and valuable methods for evaluating the pertubations in cell function resulting from increased oxidative stress. Presented in a user-friendly, step-by-step format, these readily reproducible techniques cover both free radical-derived and antioxidant biomarkers. The methodologies demonstrated include ELISA, HPLC, infrared spectroscopy, gas chromatography-mass spectroscopy, immunoblotting, electroelution fractionation, isoelectric focusing, voltametry, and electron paramagnetic resonance imaging. Special emphasis is given to the separation of complex mixtures of plant antioxidants, soft drug design to protect from toxic oxidative metabolites, in vitro oxidation conditions, and correcting for random measurement error to improve statistical interpretation. A soon-to-be-published companion volume, Oxidants and Antioxidants: Ultrastructural and Molecular Biology Protocols (0-89603-851-3), contains state-of-the-art molecular and ultrastructural methods that expand the total number of protocols to 109 assays.
Автор: Harndan Название: Cancer Biomarkers. 2007 ISBN: 0471745162 ISBN-13(EAN): 9780471745167 Издательство: Wiley Рейтинг: Цена: 21376.00 р. Наличие на складе: Поставка под заказ.
Описание: Tools, techniques, and progress in cancer biomarkers discovery The completion of a number of gene sequencing projects, recent advances in genomic and proteomic technologies, and the availability of powerful bioinformatics tools have led to promising new avenues and approaches in the search for cancer biomarkers.
Название: Handbook of biomarkers and precision medicine ISBN: 0367730057 ISBN-13(EAN): 9780367730055 Издательство: Taylor&Francis Рейтинг: Цена: 11023.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides perspective, covers recent developments in technologies that have enabled the expanded use of biomarkers, discusses biomarker characterization and validation, and applications throughout the discovery-development continuum, including Companion Diagnostic ( CDX) development.
Описание: This book is the second of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality.
Описание: This proceedings volume results from the NATO Advanced Research Workshop on `Biomarkers of Radiation in the Environment: Robust Tools for Risk Assessment (BRITE)`.
Автор: Huangxian Ju Название: Immunosensing for Detection of Protein Biomarkers ISBN: 0081019998 ISBN-13(EAN): 9780081019993 Издательство: Elsevier Science Рейтинг: Цена: 26949.00 р. Наличие на складе: Поставка под заказ.
Описание:
Immunosensing for Detection of Protein Biomarkers not only introduces the principles, methods, and classification of immunoassay, but also presents the latest achievements in areas such as electrochemical immunosensors, nanoprobe-based immunoassay, chemiluminescence immunoassay, electrochemiluminescent immunoassay, multianalyte immunoassay, optical imaging for immunoassay, signal amplification for immunoassay, and so on.
In recent years, immunosensing and immunoassay methods have attracted considerable interest due to their applications in different fields, particularly clinical diagnosis. Although a large number of academic papers in immunosensing and immunoassay have been published in different journals recently, it is still a difficult and time-consuming task for researchers, especially those new to the area, to understand the principles, methods, and research progress of immunosensing.
Based on the research experience of the authors and their research groups, this book offers readers with new research ideas to develop immunosensing methodology. As a monograph, it offers deeper and more complete coverage than review papers, which only report certain aspects of progress. Grounded in the research experience of Professor Ju's research group, the book focuses on immunosensing for detection of protein biomarkers, summarizing understanding, research, and practice on immunosensing methodology in detection of protein biomarkers.
Описание: As these begin to be deployed and administered across the globe, many now feel the virus will be brought under control and lives will eventually return to normal. This new volume will increase readers` understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns.
Описание: This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As such, this book evaluates various strategies for sample preparation for proteomic and ionomic studies in order to simplify complex serum samples and allow the quantification of chemical species (proteins and metal ions), which are potential candidates for BD biomarkers. In addition, it describes the development of a new membrane-based methodology for extracting urine proteins to be used in biomarker discovery.
Автор: David B. Peakall Название: Animal Biomarkers as Pollution Indicators ISBN: 0412402009 ISBN-13(EAN): 9780412402005 Издательство: Springer Рейтинг: Цена: 44861.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Adopting an approach similar to clinical biochemistry in human medicine, the author critically examines the use of biomarkers (the physiological or biochemical changes caused by chemicals) to indicate the state of health of wildlife.
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