Green Chemistry in Drug Discovery: From Academia to Industry, Richardson Paul F.
Автор: Li Название: The Drug Discovery Experience: Practices, Processes, and Perspectives ISBN: 0470942355 ISBN-13(EAN): 9780470942352 Издательство: Wiley Рейтинг: Цена: 12302.00 р. 17574.00-30% Наличие на складе: Есть (1 шт.) Описание: Edited by two distinguished chemists from academia and industry, this book presents an up-to-date overview of major aspects of drug discovery. It covers all ends of the discovery process from target selection to major therapeutic areas.
Автор: Caffrey Название: Parasitic Helminths: Targets, Screens, Drugs and Vaccines ISBN: 3527330593 ISBN-13(EAN): 9783527330591 Издательство: Wiley Рейтинг: Цена: 12856.00 р. 18366.00-30% Наличие на складе: Есть (1 шт.) Описание: The first title dealing with drug discovery against parasitic worms (Helminths) which include many of the major human and animal parasites. The book focusses on the development of novel drugs and vaccination strategies making it attractive for academia and industry alike.
Описание: * Greatly expanded and completely revised * Covers now not only drug application of biopharmaceuticals but also their use in diagnostics and vaccine development. * Includes material on quality control, safety issue, patent and legal regulations .
Автор: Huang Название: Case Studies in Modern Drug Discovery and Development ISBN: 0470601817 ISBN-13(EAN): 9780470601815 Издательство: Wiley Рейтинг: Цена: 19792.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Using case studies of successful drug discoveries and launches, this book helps master the necessary knowledge of the drug discovery process. It includes pharmacology, drug metabolism, biology, drug development, and clinical studies.
Автор: Harren Jhoti; Andrew R. Leach Название: Structure-based Drug Discovery ISBN: 9048171237 ISBN-13(EAN): 9789048171231 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.
Автор: Nuska Tschammer Название: Chemokines ISBN: 3319347837 ISBN-13(EAN): 9783319347837 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction.- Insights in the chemokine receptor structures and drug design approaches in chemokine receptors.- Therapeutic targeting of CXCR3 chemokine receptor by small molecules.- Allosteric modulation of chemokine receptors.- Chemokines and their receptors in CNS.- Chemokine receptors in allergy and inflammation
Автор: S. Grabley; R. Thiericke Название: Drug Discovery from Nature ISBN: 3540669477 ISBN-13(EAN): 9783540669470 Издательство: Springer Рейтинг: Цена: 33401.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text is part of a series that offers selected thematic volumes from various chemistry review series to graduates and scientists in industry and academia. This work covers the present status and future potential of natural products in drug discovery.
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more.
In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases.
Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases
Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Автор: Martinez Ana Название: Emerging Drugs and Targets for Multiple Sclerosis ISBN: 1788014502 ISBN-13(EAN): 9781788014502 Издательство: Royal Society of Chemistry Рейтинг: Цена: 33581.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An ideal reference for any student or researcher interested in drug development for neurodegenerative diseases, autoimmune diseases and MS in particular.
Описание: Peptide Therapeutics is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about Chemistry Manufacture and Control (CMC), and facilitating the development and manufacture of peptide-based drugs.
Автор: Brenneman Jehrod, Iyer Malliga R. Название: Anti-Fibrotic Drug Discovery ISBN: 178801510X ISBN-13(EAN): 9781788015103 Издательство: Royal Society of Chemistry Рейтинг: Цена: 35693.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Anti-fibrotic Drug Discovery is ideal for postgraduate students and researchers with an interest in anti-fibrotic drug discovery as well as clinicians specialising in liver, kidney, heart and lung disease, in which fibrosis plays a key role in pathology.
Название: Textbook of Drug Design and Discovery, Fifth Edition ISBN: 1498702783 ISBN-13(EAN): 9781498702782 Издательство: Taylor&Francis Рейтинг: Цена: 19906.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects.
Beginning with an introduction to drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery.
The middle six chapters provide an overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors. The authors also go through receptors (structure, function, and pharmacology), ion channels (structure and function), and neurotransmitter transporters (structure, function, and drug binding).
The following chapters address important neurotransmitter systems, GABA and glutamic acid receptors and transporter ligands, acetylcholine, histamine, dopamine and serotonin, and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.
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