Bioinformatics, Ismail, Hamid D. (nc A&t State University, North Carolina, Usa)
Автор: Eberhard Voit Название: A First Course in Systems Biology ISBN: 0815345682 ISBN-13(EAN): 9780815345688 Издательство: Taylor&Francis Рейтинг: Цена: 13014.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling, then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way, it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks, understanding the modern literature, and launching into specialized courses or projects that address biological questions using theoretical and computational means.
New topics in this edition include: default modules for model design, limit cycles and chaos, parameter estimation in Excel, model representations of gene regulation through transcription factors, derivation of the Michaelis-Menten rate law from the original conceptual model, different types of inhibition, hysteresis, a model of differentiation, system adaptation to persistent signals, nonlinear nullclines, PBPK models, and elementary modes.
The format is a combination of instructional text and references to primary literature, complemented by sets of small-scale exercises that enable hands-on experience, and large-scale, often open-ended questions for further reflection.
Автор: Sunil K. Mathur Название: Statistical Bioinformatics, ISBN: 0123751047 ISBN-13(EAN): 9780123751041 Издательство: Elsevier Science Рейтинг: Цена: 8083.00 р. Наличие на складе: Поставка под заказ.
Описание: Provides coverage of complex statistical methods in context with applications in bioinformatics. This book integrates biological, statistical and computational concepts. It includes R & SAS code. It presents Bayesian methods and the modern multiple testing principles.
Автор: Haubold Bernhard, Bцrsch-Haubold Angelika Название: Bioinformatics for Evolutionary Biologists: A Problems Approach ISBN: 3319884247 ISBN-13(EAN): 9783319884240 Издательство: Springer Рейтинг: Цена: 6567.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation.
Описание: This book proposes applications of tensor decomposition to unsupervised feature extraction and feature selection. The author posits that although supervised methods including deep learning have become popular, unsupervised methods have their own advantages. He argues that this is the case because unsupervised methods are easy to learn since tensor decomposition is a conventional linear methodology. This book starts from very basic linear algebra and reaches the cutting edge methodologies applied to difficult situations when there are many features (variables) while only small number of samples are available. The author includes advanced descriptions about tensor decomposition including Tucker decomposition using high order singular value decomposition as well as higher order orthogonal iteration, and train tenor decomposition. The author concludes by showing unsupervised methods and their application to a wide range of topics.
Allows readers to analyze data sets with small samples and many features;Provides a fast algorithm, based upon linear algebra, to analyze big data;Includes several applications to multi-view data analyses, with a focus on bioinformatics.
Автор: J. Rigden, Daniel (Ed.) Название: From Protein Structure to Function with Bioinformatics ISBN: 9402414827 ISBN-13(EAN): 9789402414820 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Поставка под заказ.
Описание: This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein interactions and on dynamic properties. Such methods help extract maximum value from new experimental structures, but can often be applied to protein models. The book also, therefore, provides comprehensive coverage of methods for predicting or inferring protein structure, covering all structural classes from globular proteins and their membrane-resident counterparts to amyloid structures and intrinsically disordered proteins. The book is split into two broad sections, the first covering methods to generate or infer protein structure, the second dealing with structure-based function annotation. Each chapter is written by world experts in the field. The first section covers methods ranging from traditional homology modelling and fold recognition to fragment-based ab initio methods, and includes a chapter, new for the second edition, on structure prediction using evolutionary covariance. Membrane proteins and intrinsically disordered proteins are each assigned chapters, while two new chapters deal with amyloid structures and means to predict modes of protein-protein interaction. The second section includes chapters covering functional diversity within protein folds and means to assign function based on surface properties and recurring motifs. Further chapters cover the key roles of protein dynamics in protein function and use of automated servers for function inference. The book concludes with two chapters covering case studies of structure prediction, based respectively on crystal structures and protein models, providing numerous examples of real-world usage of the methods mentioned previously. This book is targeted at postgraduate students and academic researchers. It is most obviously of interest to protein bioinformaticians and structural biologists, but should also serve as a guide to biologists more broadly by highlighting the insights that structural bioinformatics can provide into proteins of their interest.
Описание: This book discusses topics related to bioinformatics, statistics, and machine learning, presenting the latest research in various areas of bioinformatics.
Автор: Gбspбri Zoltбn Название: Structural Bioinformatics: Methods and Protocols ISBN: 1071602691 ISBN-13(EAN): 9781071602690 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Поставка под заказ.
Автор: Upadhyay Atul Kumar, Sowdhamini R., Patil Virupaksh U. Название: Bioinformatics for Agriculture: High-Throughput Approaches ISBN: 9813347902 ISBN-13(EAN): 9789813347908 Издательство: Springer Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It first introduces the basic concepts of bioinformatics, such as homologous sequence and gene function analyses, determination of protein structures, and discusses machine learning applications for an in-depth understanding of the desired genes and proteins based on commonly used bioinformatics software and tools, e.g.
Описание: This second edition integrates the more technical and mathematical aspects of bioinformatics with concrete examples of their application to current research problems in molecular, cellular and evolutionary biology.
Автор: Shaik Noor Ahmad, Hakeem Khalid Rehman, Banaganapalli Babajan Название: Essentials of Bioinformatics, Volume II: In Silico Life Sciences: Medicine ISBN: 3030183777 ISBN-13(EAN): 9783030183776 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting large multidimensional biological data by utilizing advanced computational methods. Despite its enormous potential, bioinformatics is not widely integrated into the academic curriculum as most life science students and researchers are still not equipped with the necessary knowledge to take advantage of this powerful tool. Hence, the primary purpose of our book is to supplement this unmet need by providing an easily accessible platform for students and researchers starting their career in life sciences. This book aims to avoid sophisticated computational algorithms and programming. Instead, it focuses on simple DIY analysis and interpretation of biological data with personal computers. Our belief is that once the beginners acquire these basic skillsets, they will be able to handle most of the bioinformatics tools for their research work and to better understand their experimental outcomes. Our second title of this volume set In Silico Life Sciences: Medicine provides hands-on experience in analyzing high throughput molecular data for the diagnosis, prognosis, and treatment of monogenic or polygenic human diseases. The key concepts in this volume include risk factor assessment, genetic tests and result interpretation, personalized medicine, and drug discovery. This volume is expected to train readers in both single and multi-dimensional biological analysis using open data sets, and provides a unique learning experience through clinical scenarios and case studies.
Описание: This book constitutes selected papers of the Third International Conference on Data Science, Medicine and Bioinformatics, IDMB 2019, held in Nanning, China, in June 2019.
Описание: This book constitutes the proceedings of the 16th International Symposium on Bioinformatics Research and Applications, ISBRA 2020, held in Moscow, Russia, in December 2020. The 23 full papers and 18 short papers presented in this book were carefully reviewed and selected from 131 submissions.
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