Описание: What every neuroscientist should know about the mathematical modeling of excitable cells. Combining empirical physiology and nonlinear dynamics, this text provides an introduction to the simulation and modeling of dynamic phenomena in cell biology and neuroscience. It introduces mathematical modeling techniques alongside cellular electrophysiology. Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ligand-gated ion channels, intracellular calcium signalling, and electrical bursting in neurons and other excitable cell types. It introduces mathematical modeling techniques such as ordinary differential equations, phase plane, and bifurcation analysis of single-compartment neuron models. With analytical and computational problem sets, this book is suitable for life sciences majors, in biology to neuroscience, with one year of calculus, as well as graduate students looking for a primer on membrane excitability and calcium signalling.
Описание: This research book presents the use of computational intelligence paradigms in the bioprocess-related tasks of modeling, supervision, monitoring and control, diagnostic, learning and optimization. All have applications to a wide variety of other areas.
Автор: Jiyuan Tu; Kiao Inthavong; Kelvin Kian Loong Wong Название: Computational Hemodynamics – Theory, Modelling and Applications ISBN: 9402407421 ISBN-13(EAN): 9789402407426 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book’s approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.
Описание: This book describes the feasibility of using molecular dynamics as a screening technique to identify the stability of HydA1 and PetF interactions. Structure-based computational approaches are necessary to recognize and characterize protein-protein complexes and their functions. It introduces the idea that for specific proteins, homology modeling is the most effective technique and that docking algorithms are an increasingly powerful tool for providing a detailed explanation of such interactions. This book is a useful source of information on biomass-based biofuels for researchers in the field of bio-hydrogen and bioinformatics techniques. Biofuel and bioenergy produced from unicellular microalgae Chlamydomonas reinhardtii is a clean energy source and providing information about functional optimization in HydA1 and PetF interactions will help researchers to adopt swift screening methods to identify key protein complexes and their functions. The book also provides an introduction to hydrogenases and associated Chlamydomonas reinhardtii, which is a useful model microorganism for research on biofuel production. The book focuses on the in silico methods such as phylogenetic studies, homology modeling, molecular docking, electrostatic studies and conformational analysis, which have the potential to become the most cost-effective methods for bio-fuel production. This book provides a valuable resource to senior undergraduate and graduate students, researchers, professionals and other interested individuals or groups working in the area of bioenergy with special reference to microalgal biofuel.
Описание: Written by the author of "HPLC: A Practical Guide" (RSC, 1999),this book presents the possibilities for characterising biological applications by combining analytical and computational chemistries.
Автор: H.A. Mastebroek; J.E. Vos Название: Plausible Neural Networks for Biological Modelling ISBN: 9401038643 ISBN-13(EAN): 9789401038645 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Standard artificial neural networks are constructed from `units` (roughly similar to neurons) that transmit their `activity` (similar to membrane potentials or to mean firing rates) to other units via `weight factors` (similar to synaptic coupling efficacies).
Автор: Yongxian Wang, Zhenghua Wang Название: Proteomics and Biological Networks ISBN: 311046117X ISBN-13(EAN): 9783110461176 Издательство: Walter de Gruyter Цена: 22305.00 р. Наличие на складе: Нет в наличии.
Описание: This book presents molecular biology knowledge and mathematical theories of frequently-used algorithms in sequence comparison, gene finding, sequence evolution and structuring phylogenetic tree.
Computational Approaches for Studying Enzyme Mechanism, Part B is the first of two volumes in the Methods in Enzymology series that focuses on computational approaches for studying enzyme mechanism. The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences.
Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of the life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, genetics, and other fields of study.
Автор: Voth, Gregory Название: Computational Approaches for Studying Enzyme Mechanism,577 ISBN: 012805347X ISBN-13(EAN): 9780128053478 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Computational Approaches for Studying Enzyme Mechanism Part A, is the first of two volumes in the Methods in Enzymology series, focusses on computational approaches for studying enzyme mechanism.
The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences.
Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, and genetics to name a few.
Focuses on computational approaches for studying enzyme mechanism
Continues the legacy of this premier serial with quality chapters authored by leaders in the field
Covers research methods in intermediate filament associated proteins, and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers
Автор: Matesh N. Varma; Aloke Chatterjee Название: Computational Approaches in Molecular Radiation Biology ISBN: 0306449951 ISBN-13(EAN): 9780306449956 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
