Автор: Amine Kamen, Laura Cervera Название: Bioprocessing of Viral Vaccines ISBN: 1032132116 ISBN-13(EAN): 9781032132112 Издательство: Taylor&Francis Рейтинг: Цена: 22202.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines.
Автор: M. Zouhair Atassi Название: Immunobiology of Proteins and Peptides VI ISBN: 1468460021 ISBN-13(EAN): 9781468460025 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The articles in this volume represent papers delivered by invited speakers at the 6th International Symposium on the Immunobiology of Proteins and Peptides.
Автор: Yu Название: mRNA Vaccines ISBN: 3031180690 ISBN-13(EAN): 9783031180699 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The formulation and the technological advancements in RNA biology, chemistry, stability, and encapsulated delivery systems that have enabled the development of fully synthetic mRNA vaccines are discussed in this volume. The applications of the mRNA technology is covered, focusing on infectious diseases but also touching on other indications, such as immunotherapies and molecular therapies. Potent and long-lasting immune responses observed in animal models, encouraging data from early human clinical studies, together with the success of two mRNA-based COVID-19 vaccines support the use of mRNA-based vaccination as an attractive alternative to conventional vaccine approaches. Consequently, the development progress of the technology, particularly on production, capabilities, and clinical development is reviewed. Topics on safety, regulatory issues, and possible challenges to the mRNA vaccination approach round off this book. Thanks to their high potency, the prospect for generic, low-cost manufacturing processes, and entirely synthetic nature, the future for mRNA vaccines is highly promising. Importantly, mRNA vaccines have the potential to minimize the time between pathogen identification and vaccine release with a huge impact on public health. As the mRNA-based vaccination technology has been progressing rapidly, the book is intended to be an end-to-end review series, covering everything from basic RNA biology and preclinical studies to the manufacturing strategy, clinical development and regulatory approval. It provides established RNA researchers and developers with updates on the latest advancements in the field and allows for a quick but comprehensive overview of this transformative technology, its application, and future potential.
Автор: Reich Jennifer A. Название: Calling the Shots: Why Parents Reject Vaccines ISBN: 147981279X ISBN-13(EAN): 9781479812790 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 11161.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Winner, 2018 Donald W. Light Award for Applied Medical Sociology, American Sociological Association Medical Sociology Section Winner, 2018 Distinguished Scholarship Award presented by the Pacific Sociology Association Honorable Mention, 2017 ESS Mirra Komarovsky Book Award presented by the Eastern Sociological Society Outstanding Book Award for the Section on Altruism, Morality, and Social Solidarity presented by the American Sociological Association A rich, multi-faceted examination into the attitudes and beliefs of parents who choose not to immunize their children The measles outbreak at Disneyland in December 2014 spread to a half-dozen U.S. states and sickened 147 people. It is just one recent incident that the medical community blames on the nation’s falling vaccination rates. Still, many parents continue to claim that the risks that vaccines pose to their children are far greater than their benefits. Given the research and the unanimity of opinion within the medical community, many ask how such parents—who are most likely to be white, college educated, and with a family income over $75,000—could hold such beliefs.For over a decade, Jennifer Reich has been studying the phenomenon of vaccine refusal from the perspectives of parents who distrust vaccines and the corporations that make them, as well as the health care providers and policy makers who see them as essential to ensuring community health. Reich reveals how parents who opt out of vaccinations see their decision: what they fear, what they hope to control, and what they believe is in their child’s best interest. Based on interviews with parents who fully reject vaccines as well as those who believe in “slow vax,” or altering the number of and time between vaccinations, the author provides a fascinating account of these parents’ points of view. Placing these stories in dialogue with those of pediatricians who see the devastation that can be caused by vaccine-preventable diseases and the policy makers who aim to create healthy communities, Calling the Shots offers a unique opportunity to understand the points of disagreement on what is best for children, communities, and public health, and the ways in which we can bridge these differences.
Автор: Joseph Domachowske, Manika Suryadevara Название: Vaccines: A Clinical Overview and Practical Guide ISBN: 3030584135 ISBN-13(EAN): 9783030584139 Издательство: Springer Цена: 11878.00 р. Наличие на складе: Поставка под заказ.
Описание: This book is designed to provide easy-to-read and basic information about vaccines for those undertaking a vaccine course or for medical providers seeking to improve their skills.
Название: Cancer Vaccines ISBN: 0367387557 ISBN-13(EAN): 9780367387556 Издательство: Taylor&Francis Рейтинг: Цена: 3520.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Recent advances in immunology and biology have opened new horizons in cancer therapy, included in the expanding array of cancer treatment options, which are immunotherapies, or cancer vaccines, for both solid and blood borne cancers. Cancer Vaccines: Challenges and Opportunities in Translation is the first text in the field to bring immunotherapy treatments from the laboratory trial to the bedside for the practicing oncologist.
Cancer Vaccines: Challenges and Opportunities in Translation:
Critically analyzes the most promising classes of investigational immunotherapies, integrating their scientific rationale and clinical potential
Discusses theranostics as pertaining to immunotherapy, i.e., using molecular diagnostics to identify patients that would most likely benefit from a therapy
Presents the new paradigm of biomarker guided R&D and clinical development in immunotherapy of cancer
Reviews bottlenecks in translational process of immunotherapies and offers strategies to resolve them
Автор: Giese Matthias Название: Molecular Vaccines ISBN: 331900977X ISBN-13(EAN): 9783319009773 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines all aspects of global molecular vaccine research and development. It describes the development of new vaccines from bench to preclinical to clinical studies and launch to the market under EMA and FDA guidelines.
Автор: Begg, Norman Название: Remarkable story of vaccines ISBN: 1032301988 ISBN-13(EAN): 9781032301983 Издательство: Taylor&Francis Рейтинг: Цена: 9645.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This remarkable book tells you everything you need to know about vaccines. Having nearly 40 years` experience of the subject, the author covers the history of vaccines, how they work, how research is carried out, their safety, how they are used in society, the inside track on COVID-19, and what the future holds.
Описание: In 2014 Barbados introduced a vaccine to prevent certain strains of the human papillomavirus (HPV) and reduce the risk of cervical cancer in young women. Despite the disproportionate burden of cervical cancer in the Caribbean, many Afro-Barbadians chose not to immunize their daughters. In Suspicion, Nicole Charles reframes Afro-Barbadian vaccine refusal from a question of hesitancy to one of suspicion. Drawing on ethnographic fieldwork, black feminist theory, transnational feminist studies and science and technology studies, Charles foregrounds Afro-Barbadians' gut feelings and emotions and the lingering trauma of colonial and biopolitical violence. She shows that suspicion, far from being irrational, is a fraught and generative affective orientation grounded in concrete histories of mistrust of government and coercive medical practices foisted on colonized peoples. By contextualizing suspicion within these longer cultural and political histories, Charles troubles traditional narratives of vaccine hesitancy while offering new entry points into discussions on racialized biopolitics, neocolonialism, care, affect, and biomedicine across the Black diaspora.
Duke University Press Scholars of Color First Book Award recipient
Автор: Almeida de Sousa Название: DNA Vaccines: Methods and Protocols ISBN: 1071608711 ISBN-13(EAN): 9781071608715 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details practical procedures on the latest DNA vaccine technology. Chapters guide readers through methods and protocols on DNA vaccine design, the adjuvant influence, production and purification methodologies, delivery systems, and approaches of the influence of DNA vaccines in the immunological response performance and in the cancer immunotherapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, DNA Vaccines: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Автор: Kramps Thomas, Elbers Knut Название: RNA Vaccines: Methods and Protocols ISBN: 1493982141 ISBN-13(EAN): 9781493982141 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Introduction to RNA Vaccines
Thomas Kramps and Knut Elbers
Part I: Self-replicating RNA Vectors
2. Self-replicating RNA
Birke A. Tews and Gregor Meyers
3. Self-replicating RNA Vaccine Delivery to Dendritic Cells
Thomas Dйmoulins, Pavlos C. Englezou, Panagiota Milona, Nicolas Ruggli, Nicola Tirelli, Chantal Pichon, Cйdric Sapet, Thomas Ebensen, Carlos A. Guzmбn, and Kenneth C. McCullough
4. Plant Expression of Trans-encapsidated Viral Nanoparticle Vaccines with Animal RNA Replicons
Yiyang Zhou, Alison A. McCormick, and Christopher M. Kearney
Part II: Non-replicating mRNA Vectors
5. RNActive(R) Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines
Susanne Rauch, Johannes Lutz, Aleksandra Kowalczyk, Thomas Schlake, and Regina Heidenreich
6. Nucleoside Modified mRNA Vaccines for Infectious Diseases
Norbert Pardi and Drew Weissman
7. Generation and Evaluation of Prophylactic mRNA Vaccines against Allergy
Richard Weiss, Sandra Scheiblhofer, and Josef Thalhamer
Part III: Adjuvantation and Delivery
8. Measuring the Adjuvant Activity of RNA Vaccines
Norbert Pardi and Drew Weissman
9. Generation of Immunostimulating 130 nm Protamine-RNA Nanoparticles
Marina Tusup and Steve Pascolo
10. Electroporation of mRNA as Universal Technology Platform to Transfect a Variety of Primary Cells with Antigens and Functional Proteins
Kerstin F. Gerer, Stefanie Hoyer, Jan Dцrrie, and Niels Schaft
11. Adjuvant-Enhanced mRNA Vaccines
Lukasz Bialkowski, Kevin Van der Jeught, Dries Renmans, Alexia van Weijnen, Carlo Heirman, Marleen Keyaerts, Karine Breckpot, and Kris Thielemans
12. Enhanced Delivery of DNA or RNA Vaccines by Electroporation
Kate E. Broderick and Laurent M. Humeau
Part IV: Preclinical and Clinical Development
13. The European Regulatory Environment of RNA-Based Vaccines
Thomas Hinz, Kajo Kallen, Cedrik M. Britten, Bruno Flamion, Ulrich Granzer, Axel Hoos, Christoph Huber, Samir Khleif, Sebastian Kreiter, Hans-Georg Rammensee, Ugur Sahin, Harpreet Singh-Jasuja, Цzlem Tьreci, and Ulrich Kalinke
14. Discovery and Subtyping of Neo-Epitope Specific T-cell Responses for Cancer Immunotherapy: Addressing the Mutanome
Mustafa Diken, Mathias Vormehr, Christian Grunwitz, Sebastian Kreiter, Цzlem Tьreci, and Ugur Sahin
15. Considerations for Producing mRNA Vaccines for Clinical Trials
Andreas Schmid
16. Nonclinical Safety Testing of RNA Vaccines
Gundel Hager
17. Immunotherapy of Uveal Melanoma: Vaccination Against Cancer
Описание: In recent decades, changes in pertussis epidemiology have been noted, likely related to the use of acellular pertussis vaccines, which in many countries have replaced older-generation, whole-cell pertussis vaccines.
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