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RNA Vaccines: Methods and Protocols, Kramps Thomas, Elbers Knut


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Автор: Kramps Thomas, Elbers Knut
Название:  RNA Vaccines: Methods and Protocols
ISBN: 9781493982141
Издательство: Springer
Классификация:
ISBN-10: 1493982141
Обложка/Формат: Paperback
Страницы: 282
Вес: 0.52 кг.
Дата издания: 07.07.2018
Серия: Methods in molecular biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 28 tables, color; 26 illustrations, color; 16 illustrations, black and white; xi, 282 p. 42 illus., 26 illus. in color.
Размер: 25.40 x 17.78 x 1.57 cm
Читательская аудитория: General (us: trade)
Подзаголовок: Methods and protocols
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание:

1. Introduction to RNA Vaccines

Thomas Kramps and Knut Elbers

Part I: Self-replicating RNA Vectors

2. Self-replicating RNA

Birke A. Tews and Gregor Meyers

3. Self-replicating RNA Vaccine Delivery to Dendritic Cells

Thomas Dйmoulins, Pavlos C. Englezou, Panagiota Milona, Nicolas Ruggli, Nicola Tirelli, Chantal Pichon, Cйdric Sapet, Thomas Ebensen, Carlos A. Guzmбn, and Kenneth C. McCullough

4. Plant Expression of Trans-encapsidated Viral Nanoparticle Vaccines with Animal RNA Replicons

Yiyang Zhou, Alison A. McCormick, and Christopher M. Kearney

Part II: Non-replicating mRNA Vectors

5. RNActive(R) Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines

Susanne Rauch, Johannes Lutz, Aleksandra Kowalczyk, Thomas Schlake, and Regina Heidenreich

6. Nucleoside Modified mRNA Vaccines for Infectious Diseases

Norbert Pardi and Drew Weissman

7. Generation and Evaluation of Prophylactic mRNA Vaccines against Allergy

Richard Weiss, Sandra Scheiblhofer, and Josef Thalhamer

Part III: Adjuvantation and Delivery

8. Measuring the Adjuvant Activity of RNA Vaccines

Norbert Pardi and Drew Weissman

9. Generation of Immunostimulating 130 nm Protamine-RNA Nanoparticles

Marina Tusup and Steve Pascolo

10. Electroporation of mRNA as Universal Technology Platform to Transfect a Variety of Primary Cells with Antigens and Functional Proteins

Kerstin F. Gerer, Stefanie Hoyer, Jan Dцrrie, and Niels Schaft

11. Adjuvant-Enhanced mRNA Vaccines

Lukasz Bialkowski, Kevin Van der Jeught, Dries Renmans, Alexia van Weijnen, Carlo Heirman, Marleen Keyaerts, Karine Breckpot, and Kris Thielemans

12. Enhanced Delivery of DNA or RNA Vaccines by Electroporation

Kate E. Broderick and Laurent M. Humeau

Part IV: Preclinical and Clinical Development

13. The European Regulatory Environment of RNA-Based Vaccines

Thomas Hinz, Kajo Kallen, Cedrik M. Britten, Bruno Flamion, Ulrich Granzer, Axel Hoos, Christoph Huber, Samir Khleif, Sebastian Kreiter, Hans-Georg Rammensee, Ugur Sahin, Harpreet Singh-Jasuja, Цzlem Tьreci, and Ulrich Kalinke

14. Discovery and Subtyping of Neo-Epitope Specific T-cell Responses for Cancer Immunotherapy: Addressing the Mutanome

Mustafa Diken, Mathias Vormehr, Christian Grunwitz, Sebastian Kreiter, Цzlem Tьreci, and Ugur Sahin

15. Considerations for Producing mRNA Vaccines for Clinical Trials

Andreas Schmid

16. Nonclinical Safety Testing of RNA Vaccines

Gundel Hager

17. Immunotherapy of Uveal Melanoma: Vaccination Against Cancer

Mirko Kummer and Beatrice Schuler-Thurner





RNA Vaccines

Автор: Kramps
Название: RNA Vaccines
ISBN: 1493964798 ISBN-13(EAN): 9781493964796
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume provides an overview of the field and practical hints for vaccinologists in academia and industry. Chapters provide protocols on self-replicating RNA vectors, non-replication mRNA vectors, adjuvantation and delivery, and preclinical and clinical development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA Vaccines: Methods and Protocols aims to increased collaboration on RNA vaccines between basic and applied scientists in academia, government, and industry to develop future solutions for today’s challenges.

Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines

Автор: Darren R. Flower; Yvonne Perrie
Название: Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines
ISBN: 1489997954 ISBN-13(EAN): 9781489997951
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This book details the discovery of antigens and adjuvants within the context of reverse vaccinology. It explores ways to make vaccines more effective.

Vaccines for Invasive Fungal Infections

Автор: Markus Kalkum; Margarita Semis
Название: Vaccines for Invasive Fungal Infections
ISBN: 1493971034 ISBN-13(EAN): 9781493971039
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This detailed volume focuses on the development of mycosis vaccines via the most common etiological agents of mycoses, such as Aspergillus and Candida species, followed by Cryptococcus, dimorphic fungi, and members of Mucoraceae family of fungi.

Vaccines: Are they Worth a Shot?

Автор: Andrea Grignolio; Joan Rundo
Название: Vaccines: Are they Worth a Shot?
ISBN: 3319681052 ISBN-13(EAN): 9783319681054
Издательство: Springer
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Цена: 4191.00 р.
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Описание: 1. The parents of unvaccinated children

1.1. The 80s, the beginning of the crisis (or resistance)

1.2. Education about risk

1.3. Social changes: The doctor-patient relationship in jeopardy

1.4. Unexpected impact of late fecundity

2. A brief history of the anti-vaccination movements

2.1. The anti-vaccination movements between 1700 and 1800: Roots of obligation and objection

2.2. The anti-vaccination movements in 1900: Media and politics

3. Web alarms: autism, mercury and immune overload

3.1. Conspiracy on the Internet: separating fact from fiction

3.2. Economic criticism: Big Pharma and the allure of patents

3.3. Logic errors: the precautionary principle and the equal balance mistake

3.4. False or manipulated data: Autism

3.5. Prejudices and ideologies: Purported overload and weakening of the immune system

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4. The antivax "experts" five ways to recognize them

4.1. Alternative philosophies: homeopathy, anthroposophy and Waldarf -Steiner schools

4.2. The "alternative therapies" Five clues that reveal a charlatan

5. Past, present, and future of vaccines

5.1. Evolutionary history of naturally acquired immunity

5.2. Artificially acquired immunity: success and safety of vaccines

5.3. Therapeutic vaccines of the future: cancer and neurodegenerative diseases

6. Conclusions

6.1. A new alliance between scientists and citizens for a "knowledge society"

6.2. Some tools for good communication strategies to combat anti-vaccination resistance
Veterinary Vaccines

Автор: R. Pandey; S. H?glund; G. Prasad
Название: Veterinary Vaccines
ISBN: 1461392284 ISBN-13(EAN): 9781461392286
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out.

Recombinant Virus Vaccines: Methods and Protocols

Автор: Ferran Maureen C., Skuse Gary R.
Название: Recombinant Virus Vaccines: Methods and Protocols
ISBN: 1493983237 ISBN-13(EAN): 9781493983230
Издательство: Springer
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Цена: 15372.00 р.
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Описание:

Preface...
Table of Contents...
Contributing Authors...

Part I Double-Stranded DNA Viruses

1. Development of Novel Vaccines Against Infectious Diseases Based on Chimpanzee Adenoviral Vector
Chao Zhang, Yudan Chi, and Dongming Zhou

2. Development of Recombinant Canarypox Viruses Expressing Immunogens
Dйbora Garanzini, Marнa Paula Del Mйdico-Zajac, and Gabriela Calamante


3. Fowl Adenovirus-Based Vaccine Platform
Juan C. Corredor, Yanlong Pei, and Йva Nagy

4. Development of Recombinant HSV-Based Vaccine Vectors
Richard Voellmy and David Bloom

5. Generating Recombinant Pseudorabies Virus for Use as a Vaccine Platform
Feifei Tan, Xiangdong Li, and Kegong Tian

6. Generation and Production of Modified Vaccinia Virus Ankara (MVA) as a Vaccine Vector
Vincent Pavot, Sarah Sebastian, Alison V. Turner, Jake Matthews, and Sarah C. Gilbert

7. Poxvirus Safety Analysis in the Pregnant Mouse Model, Vaccinia and Raccoonpox Viruses
Rachel L. Roper

Part II Negative Sense Single-Stranded RNA viruses

8. Development of Recombinant Arenavirus-Based Vaccines
Luis Martнnez-Sobrido and Juan Carlos de la Torre

9. Development of Recombinant Measles Virus-Based Vaccines
Michael D. Mьhlebach and Stefan Hutzler

10. Recombinant Tri-Segmented Pichinde Virus as a Novel Live Viral Vaccine Platform
Rekha Dhanwani, Hinh Ly, and Yuying Liang

11. Human Rhinovirus-A1 as an Expression Vector
Khamis Tomusange, Danushka Wijesundara, Eric James Gowans, and Branka Grubor-Bauk

12. Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms
John B. Ruedas and John H. Connor

Part III Positive Sense Single-Stranded RNA viruses

13. Alphavirus-Based Vaccines
Kenneth Lundstrom

Part IV Bacteriophage

14. Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform
Jonelle L. Mattiacio, Matt Brewer, and Stephen Dewhurst

15. Bacteriophage T4 as a Nanoparticle Platform to Display and Deliver Pathogen Antigens: Construction of an Effective Anthrax Vaccine
Pan Tao, Qin Li, Sathish Shivachandra, and Venigalla B. Rao

Advanced Vaccine Research: Methods for the Decade of Vaccines

Автор: Bagnoli Fabio, Rappuoli Rino
Название: Advanced Vaccine Research: Methods for the Decade of Vaccines
ISBN: 1910190039 ISBN-13(EAN): 9781910190036
Издательство: Неизвестно
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Цена: 45980.00 р.
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Antiviral agents, vaccines, and immunotherapies

Название: Antiviral agents, vaccines, and immunotherapies
ISBN: 0367393743 ISBN-13(EAN): 9780367393748
Издательство: Taylor&Francis
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Цена: 9492.00 р.
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Описание: Providing an analysis of the benefits and limitations of every available drug, vaccine and immunotherapy used to control and prevent antiviral diseases, this unique and genuinely comprehensive text is unlike any other current reference of its kind.

Human Vaccines

Автор: Modjarrad, Kayvon
Название: Human Vaccines
ISBN: 0128023023 ISBN-13(EAN): 9780128023020
Издательство: Elsevier Science
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Цена: 13980.00 р.
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Описание:

Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics--among other disciplines--that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens.

For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed

Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology.

  • Introduces new topics in vaccine immunology in the context vaccine design and production
  • Consolidates the growing body of knowledge on new vaccine technologies that have only emerged in the past 2 - 3 decades
  • Reviews the currently licensed vaccines that have utilized leading-edge technologies and how this has translated into improved efficacy and safety
  • Provides a broad overview of innovative vaccine technologies, including immunological aspects
Immunopotentiators in Modern Vaccines

Автор: Schijns, Virgil E
Название: Immunopotentiators in Modern Vaccines
ISBN: 012804019X ISBN-13(EAN): 9780128040195
Издательство: Elsevier Science
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Цена: 18696.00 р.
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Описание:

Immunopotentiators in Modern Vaccines, Second Edition, provides in-depth insights and overviews of the most successful adjuvants, those that have been included in licensed products, also covering the most promising technologies that have emerged in recent years. In contrast to existing books on the subject, the chapters here provide summaries of key data on the mechanisms of action of the individual vaccine adjuvants.

In addition, the book covers key aspects of how the technologies might be further developed and what might be their limitations, while also giving an overview of what made the most advanced adjuvant technologies successful.

Prospects of Plant-Based Vaccines in Veterinary Medicine

Автор: Jacqueline MacDonald
Название: Prospects of Plant-Based Vaccines in Veterinary Medicine
ISBN: 3030079414 ISBN-13(EAN): 9783030079413
Издательство: Springer
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Цена: 20962.00 р.
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Описание:

This book provides an in-depth explanation of the advantages and current limitations of recombinant plant-made vaccines for use in veterinary medicine, including for livestock, pets, and wild animals. Written by top scientists in the field, it discusses the background to and latest scientific advances in plant-made vaccines for the most commonly targeted veterinary infections.
With the recent high-profile research into recombinant plant-made therapeutics for Ebola and Zika viruses, it is likely that the products will be commercialized and widely used in the future. Plant-made therapeutics have a variety of advantages over those made in traditional systems; however, their most fruitful application may be in veterinary medicine, due to less stringent regulations and a greater need for low-cost products.
DNA Vaccines: Methods and Protocols

Автор: Almeida de Sousa
Название: DNA Vaccines: Methods and Protocols
ISBN: 1071608711 ISBN-13(EAN): 9781071608715
Издательство: Springer
Рейтинг:
Цена: 18167.00 р.
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Описание: This volume details practical procedures on the latest DNA vaccine technology. Chapters guide readers through methods and protocols on DNA vaccine design, the adjuvant influence, production and purification methodologies, delivery systems, and approaches of the influence of DNA vaccines in the immunological response performance and in the cancer immunotherapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, DNA Vaccines: Methods and Protocols aims to ensure successful results in the further study of this vital field.


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