Our Genes: A Philosophical Perspective on Human Evolutionary Genomics, Rasmus Gronfeldt Winther
Автор: Strachan Название: Human Molecular Genetics ISBN: 0815345895 ISBN-13(EAN): 9780815345893 Издательство: Taylor&Francis Рейтинг: Цена: 12095.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.
Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.
Key features:
Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology
Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms
Summary boxes at the end of each chapter provide clear learning points
Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study
Reorganized into five sections for improved access to related topics
Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics
A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.
Автор: Wall-scheffler, Cara M. (seattle Pacific University) Kurki, Helen K. (university Of Victoria, British Columbia) Auerbach, Benjamin M. (university Of T Название: Evolutionary biology of the human pelvis ISBN: 1107199573 ISBN-13(EAN): 9781107199576 Издательство: Cambridge Academ Рейтинг: Цена: 11563.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A novel synthesis of information relating to the biology, function and evolution of the human pelvis, which is crucial for both locomotion and childbirth. It collates evidence concerning comparative anatomy, clinical and experimental studies, and quantitative evolutionary models, and provides an assessment of existing paradigms of pelvic evolution.
Автор: Wagner, Gunter P. Название: Homology, genes, and evolutionary innovation ISBN: 0691180679 ISBN-13(EAN): 9780691180670 Издательство: Wiley Рейтинг: Цена: 5069.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
A major synthesis of homology, written by a top researcher in the field
Homology--a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird's wing--is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution.
G nter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks--that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers.
The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.
Описание: Offers a close to complete view on topics that have been addressed from an evolutionary angle, with a focus on social science. A broad readership, including academics from natural to social sciences, and a general audience, are guaranteed to find a lot to their taste in the book.
Автор: Boaz, Noel T. (international Institute For Human Evolutionary Research, Spokane) Ciochon, Russell L. (professor And Chairman, Department Of Anthropolo Название: Dragon bone hill ISBN: 0195152913 ISBN-13(EAN): 9780195152913 Издательство: Oxford Academ Рейтинг: Цена: 3721.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Researching the famous fossil site of Dragon Bone Hill in China, scientists Noel T. Boaz and Russell L. Ciochon retell the story of the cave`s unique species of early human, Homo erectus.
A nuanced discussion of human enhancement that argues for enhancement that does not significantly exceed what is currently possible for human beings.
The transformative potential of genetic and cybernetic technologies to enhance human capabilities is most often either rejected on moral and prudential grounds or hailed as the future salvation of humanity. In this book, Nicholas Agar offers a more nuanced view, making a case for moderate human enhancement -- improvements to attributes and abilities that do not significantly exceed what is currently possible for human beings. He argues against radical human enhancement, or improvements that greatly exceed current human capabilities.
Agar explores notions of transformative change and motives for human enhancement; distinguishes between the instrumental and intrinsic value of enhancements; argues that too much enhancement undermines human identity; considers the possibility of cognitively enhanced scientists; and argues against radical life extension. Making the case for moderate enhancement, Agar argues that many objections to enhancement are better understood as directed at the degree of enhancement rather than enhancement itself. Moderate human enhancement meets the requirement of truly human enhancement. By radically enhancing human cognitive capabilities, by contrast, we may inadvertently create beings ("post-persons") with moral status higher than that of persons. If we create beings more entitled to benefits and protections against harms than persons, Agar writes, this will be bad news for the unenhanced. Moderate human enhancement offers a more appealing vision of the future and of our relationship to technology.
Автор: Wells, Jonathan C. K. (institute Of Child Health, University College London) Название: Evolutionary biology of human body fatness ISBN: 1108822592 ISBN-13(EAN): 9781108822596 Издательство: Cambridge Academ Рейтинг: Цена: 6970.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Timely analysis of medical and evolutionary data to address the role body fat has played in human biology, including in the current obesity epidemic. Obesity researchers from human biologists and anthropologists to health professionals will benefit from this comprehensive evolutionary approach to examining human body composition.
Описание: Combines natural science and philosophy to attract academic and general readers interested in philosophical questions about who we are and how we are connected. By investigating current trends in genomic research, Our Genes illustrates the potential and the limitations of genes to inform our sense of identity.
Описание: An illuminating, entertaining tour of the physical imperfections that make us human
We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often--two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake.
As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.
A rollicking, deeply informative tour of humans' four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.
Автор: Naruya Saitou Название: Introduction to Evolutionary Genomics ISBN: 1447171594 ISBN-13(EAN): 9781447171591 Издательство: Springer Рейтинг: Цена: 8384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes core processes of replication, mutation, neutral evolution and natural selection, genome evolution in prokaryotes, eukaryotes, vertebrates and humans, genome sequencing amd more, offering worked-out examples and extensive appendices.
Автор: Charlesworth Brian Название: Elements of Evolutionary Genetics ISBN: 0981519423 ISBN-13(EAN): 9780981519425 Издательство: Macmillan Learning Рейтинг: Цена: 12472.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data.
Автор: Hartl, D.L. Название: Essential Genetics: a Genomics Perspective ISBN: 1449686885 ISBN-13(EAN): 9781449686888 Издательство: Jones & Bartlett Рейтинг: Цена: 11614.00 р. Наличие на складе: Поставка под заказ.
Описание: Every new copy includes access to the student companion website Updated throughout to reflect the latest discoveries in this fast-paced field, Essential Genetics: A Genomics Perspective, Sixth Edition, provides an accessible, student-friendly introduction to modern genetics. Designed for the shorter, less comprehensive course, the Sixth Edition presents carefully chosen topics that provide a solid foundation to the basic understanding of gene mutation, expression, and regulation. It goes on to discuss the development and progression of genetics as a field of study within a societal and historical context. The Sixth Edition includes new learning objectives within each chapter which helps students identify what they should know as a result of their studying and highlights the skills they should acquire through various practice problems. What's new in the Sixth Edition? Chapter 1 includes a new section on the origin of life Chapter 2 includes a revised discussion of the complementation test and how it is used to determine whether two mutations have defects in the same gene Chapter 3 incorporates new data showing that the folding of interphase chromatin into chromosome territories has the form of a fractal globule. It also includes a new section on progenitor cells and embryonic stem cells Chapter 4 includes a new section discussing how copy-number variation in human amylase evolved in response to increased dietary starch as well as the latest on hotspots of recombination Chapter 5 is updated with the latest information on hazards of polycarbonate food containers. It also includes a new section on the genetics of schizophrenia and autism spectrum disorder Chapter 6 includes a revised section on restriction mapping and also discusses the newest massively parallel DNA sequencing technologies that can yield the equivalent of 200 human genomes' worth of DNA sequence in a single sequencing run Chapter 7 has been updated with a shortened and streamlined discussion of recombination in bacteriophage Chapter 8 includes new discoveries concerning the mechanisms of intrinsic transcriptional termination as well as rho-dependent termination Chapter 9 is updated with a new section on stochastic effects on gene expression and an expanded discussion of the lactose operon. There is also a revised discussion of galactose gene regulation in yeast, as well as new sections on lon noncoding RNAs Chapter 10 includes new sections on ancient DNA sequences of the Neandertal and Denisovan genomes Chapter 11 examines master control genes in development Chapter 12 includes a new section on the repair of double-stranded breaks in DNA by nonhomologous end joining or template-directed gap repair Chapter 13 has been extensively revised with the latest data on cancer. Chapter 14 includes a new section on the detection of natural selection, as well as a new section on conservation genetics Key Features of Essential Genetics, Sixth Edition: New Learning Objectives within each chapter help students to: Identify what they should know or be able to do as a result of their study Focus on the knowledge they should have acquired from studying the chapter Guide them to identify key concepts and use them at a variety of learning levels including comprehension, application, analysis, and synthesis Highlight the skill they should acquire through practice of various problem types Each chapter includes several different types and levels of problems, including: concept, synthesis, and discussion questions, problem solving questions, and application and analysis problems. The companion Website, GeNETics on the Web, includes numerous study tools and learning resources such as animated flashcards, crosswords, and practice quizzes An electronic Student Study Guide and Solutions Manual is available, containing chapter summaries, key terms, and extra study questions, as well as worked
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