Описание: This book intends to provide an up-to-date information in the field of nanobiomedicine. The focus of the book is on the basic concepts and recent developments in the field of nanotechnology.
Автор: Madkour, Loutfy H. Название: Nucleic Acids As Gene Anticancer Drug Delivery Therapy ISBN: 0128197773 ISBN-13(EAN): 9780128197776 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery are discussed. The use of smart drug delivery systems seems to be a promising approach for developing intelligent therapeutic systems for cancer immunotherapies and is discussed in detail along with nucleic acid-targeted drug delivery combination therapy for cancer. Nucleic Acids as Gene Anticancer Drug Delivery Therapy will be a useful reference for pharmaceutical scientists, pharmacologiests, and those involved in nanotechnology and cancer research.
Автор: Yiyun Cheng Название: Polymeric Gene Delivery Systems ISBN: 331977865X ISBN-13(EAN): 9783319778655 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: ?The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
The chapter 'Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment' is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Polysaccharide-Based Nanocomposites for Gene Delivery and Tissue Engineering presents quantitative background on new polysaccharide nanocomposites in a clear and logical way, highlighting the most exciting applications in gene delivery and tissue engineering and their progress. The book focuses on the different types of polysaccharide nanocomposites for gene delivery and tissue engineering and covers polysaccharide hydrogels for tissue engineering and polysaccharide magnetic nanocomposites for gene delivery. Chapters cover various nanocomposites presented in twenty-one separate chapters. This book will be of great interest to all those researching the development and applications of polysaccharide-based nanocomposites for modeling.
As polysaccharide-based nanocomposites promise cutting-edge applications in gene delivery and tissue engineering, with their development at the forefront of modern medicine, this book is a welcome title on this exciting science.
Presents quantitative background on new polysaccharide nanocomposites for advanced medicine
Focuses on polysaccharide nanocomposites in relation to gene delivery and tissue engineering
Highlights the most exciting, leading-edge applications in gene delivery and tissue engineering
Covers polysaccharide hydrogels for tissue engineering and magnetic nanocomposites for gene delivery
Offers a logical and useful presentation of polysaccharide nanocomposites organized first by application and then by nanocomposite
Автор: Yiyun Cheng Название: Polymeric Gene Delivery Systems ISBN: 3030085597 ISBN-13(EAN): 9783030085599 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: ?The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
The chapter 'Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment' is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Название: Gene delivery systems ISBN: 1032025506 ISBN-13(EAN): 9781032025506 Издательство: Taylor&Francis Рейтинг: Цена: 19906.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume covers the development of gene therapy, the technology involved, clinical applications of siRNA, non-viral vector-based mRNA delivery using nanotechnology, and RNA based vaccines for treating the infectious diseases.
Название: Gene delivery: methods and applications ISBN: 153616268X ISBN-13(EAN): 9781536162684 Издательство: Nova Science Рейтинг: Цена: 13462.00 р. Наличие на складе: Невозможна поставка.
Описание: Gene Delivery: Methods and Applications provides a comprehensive overview on viral and non-viral methods used to genetically engineer human mesenchymal stromal cells. In addition, an update on ongoing and completed clinical studies with engineered mesenchymal stromal cells will be provided, as well as a snapshot of the advances and technical challenges yet to be addressed. Next, a variety of gene delivery systems including physical transfection techniques, virus-based delivery vectors, chemically engineered delivery systems and bio-inspired vehicles are reviewed and their strengths, shortcomings and biomedical applications are discussed. Selfish DNA called transposons capable of cutting out and pasting into the host genome are active throughout the phylogenetic kingdoms. Researchers have repurposed natural transposons for use in delivering a gene-of-interest, enabling for the study of a large and growing list of preclinical gene therapy applications. As such, the authors discuss the past achievements and future challenges of this early-stage technology. The closing chapter introduces cell-penetrating peptides as an efficient tool for DNA transfection. HR9, a designed cell-penetrating peptides, containing nona-arginine flanked by cysteine and penta-histidine displayed a high penetrating ability in mammalian cells.
Автор: Copot, Dana Название: Automated Drug Delivery In Anesthesia ISBN: 0128159758 ISBN-13(EAN): 9780128159750 Издательство: Elsevier Science Рейтинг: Цена: 23749.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Automated Drug Delivery in Anesthesia provides a full review of available tools and methods on the drug delivery of anesthesia, bridging the gap between academic development, research and clinical practice. The book takes an interdisciplinary approach, pulling information about tools developed in other disciplines such as mathematics, physics, biology and system engineering and applying them to drug delivery. The book's authors discuss the missing element of complete regulatory loop of anesthesia: the sensor and model for pain pathway assessment. This is the only book which focuses specifically on the delivery of anesthesia.
Автор: Santos, Helder A. Название: Nanotechnology For Oral Drug Delivery ISBN: 0128180382 ISBN-13(EAN): 9780128180389 Издательство: Elsevier Science Рейтинг: Цена: 33013.00 р. Наличие на складе: Нет в наличии.
Описание:
Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance. In this book, a comprehensive overview of the most promising and up-to-date engineered and surface functionalized drug carrier systems, as well as opportunities for the development of novel and robust delivery platforms for oral drug administration are discussed. The relevance of controlling the physicochemical properties of the developed particle formulations, from size and shape to drug release profile are broadly reviewed. Advances in both in vitro and in vivo scenarios are discussed, focusing on the possibilities to study the biological-material interface. The industrial perspective on the production of nanotechnology-based oral drug delivery systems is also covered. Nanotechnology for Oral Drug Delivery: From Concept to Applications is essential reading for researchers, professors, advanced students and industry professionals working in the development, manufacturing and/or commercialization of nanotechnology-based systems for oral drug delivery, targeted drug delivery, controlled drug release, materials science and biomaterials, in vitro and in vivo testing of potential oral drug delivery technologies.
Название: Polymers in Drug Delivery ISBN: 0367453592 ISBN-13(EAN): 9780367453596 Издательство: Taylor&Francis Рейтинг: Цена: 9492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Together, the nano explosion and the genomic revolution are ushering in a new frontier in drug delivery. In recent years we've seen how polymers can play a crucial role in controlling the rate of drug release, enhancing solubility and uptake, and limiting degradation and toxicity. In the very near future, they may well be used to deliver gene therapy.
While Polymers in Drug Delivery offers much new insight for the veteran specialist, this work has been compiled with the non-specialist in mind. It includes contributions from many of the world's leading drug delivery specialists, yet avoids jargon and presents background information that initiates the next generation of scientists into the amazing work going on at the frontiers of this rapidly evolving science.
Targeting specific issues at the forefront of drug delivery today, this engaging volume--
- Outlines the issues that must be considered when selecting a polymer for fabricating a drug delivery agent or other medical devices
- Explains the more commonly used methods by which polymers may be characterized prior to use
- Profiles polymer matrices that have been used in the formulation of solid oral dosage forms, drug delivery scaffolds, and hydrogels
- Examines the issues surrounding the encapsulation of biologics within microspheres
- Explores the use of nanoparticulates, especially solid nanoparticles and nanocapsules prepared from largely-water-insoluble cyanoacrylate polymers
- Discusses polymeric micelles and investigates the potential of soluble polymer prodrugs and polymer nanomedicines
- Details the contribution made by polymers and dendrimers to the gene delivery effort, which may one day lead to effective treatments for largely incurable diseases
Noting a dramatic paradigm shift that is bridging the gap between materials science and life science, the editor's have compiled this volume to paint an interdisciplinary portrait of drug delivery that will challenge young scientists to turn their attention and effort towards this critical branch of biomedicine. Containing state-of-the-art information for drug delivery scientists, it is also a great choice for medical and pharmaceutical students and others seeking an in-depth introduction to the field.
Описание: Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites.
To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.
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