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Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery, Christopher T Walsh, Yi Tang


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Автор: Christopher T Walsh, Yi Tang
Название:  Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery
ISBN: 9781839165641
Издательство: Royal Society of Chemistry
Классификация:


ISBN-10: 1839165642
Обложка/Формат: Hardback
Страницы: 820
Вес: 1.78 кг.
Дата издания: 14.12.2022
Серия: Chemistry
Язык: English
Размер: 253 x 196 x 53
Читательская аудитория: College/higher education
Ключевые слова: Biochemistry,Biology, life sciences,Enzymology,Molecular biology,Organic chemistry, SCIENCE / Chemistry / Organic,SCIENCE / Life Sciences / Biochemistry,SCIENCE / Life Sciences / Molecular Biology
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Поставляется из: Англии
Описание:

Authored by leading experts in the enzymology of natural product biosynthesis, this completely revised and updated edition provides a description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era. Although some 500 000 – 600 000 natural products have been isolated and characterized over the past two centuries, there may be a 10-fold greater inventory awaiting immediate exploration based on biosynthetic gene cluster predictions. The approach of this book is to codify the chemical logic that underlies each natural product structural class as they are assembled from building blocks of primary metabolism.

This second edition integrates many new findings into the sets of principles of the first edition that parsed categories of natural product chemistries into the underlying enzymatic mechanisms and the catalytic machinery for building the varied and complex end product metabolites. New chapters include evaluation of a core set of thermodynamically activated but kinetically stable metabolites that power both primary and secondary metabolic pathways. Also, after decades of uncertainty about the existence of various pericyclase classes, a series of genome mining, heterologous expression, and enzymatic activity characterization have validated a plethora of pericyclases over the past decade. The several types of pericyclases are involved in biosynthetic complexity generation of almost every major category of natural products.

This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists. It will also be valuable to bioinformatic and computational biologists, pharmacognocists and chemical ecologists, and bioengineers and synthetic biologists.




      Старое издание
Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery

Автор: Walsh Christopher T., Tang Yi
Название: Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery
ISBN: 1788010760 ISBN-13(EAN): 9781788010764
Издательство: Marston Book Services
Цена: 17818.00 р.
Наличие на складе: Есть у поставщикаПоставка под заказ.
Описание: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.


Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery

Автор: Walsh Christopher T., Tang Yi
Название: Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery
ISBN: 1788010760 ISBN-13(EAN): 9781788010764
Издательство: Marston Book Services
Рейтинг:
Цена: 17818.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.

Carotenoids in Nature

Автор: Stange
Название: Carotenoids in Nature
ISBN: 3319391240 ISBN-13(EAN): 9783319391243
Издательство: Springer
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Цена: 32142.00 р.
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Описание: This comprehensive, edited book explores carotenoids and their important functional roles in yeast, bacteria and plants and a profound exposition on the structures of carotenoid molecules, focusing in the first of three parts on the biosynthesis of carotenoids. The regulation of carotenoid biosynthesis in photosynthesis as well as in plant, fruits, storage roots and algae is central to the second part, and discoveries about the function of carotenoids in human health feature in the third and final part. Many helpful illustrations, explanations, overviews and examples help to bring readers up to date on relevant themes including carotenogenic genes, carotenoids in fruits and metabolic engineering. The book explores where carotenoids are synthesized in nature, including in carrots and algae. Contributing expert authors examine enzyme functions and plant models, and analyze the structure of carotenoid molecules. The function of carotenoids in photosynthesis and in photosynthetic organs as well as during fruit ripening are then explored. A whole chapter is dedicated to the latest research on apocarotenoids and further chapters cover interesting and novel themes on plastid development and the epigenetic regulation that affects carotenoid synthesis in plants. The metabolic engineering of carotenoids that has been done in fruits, plants, and seeds is another area that readers can explore, along with evidences on the function of carotenoids in human nutrition, as antioxidants, as in the control of lipid metabolism and in the absorption of carotenoids. This is a highly informative and wide-ranging work which will update researchers in the field, as well as supporting students of plant physiology and biotechnology, as supplementary reading.

Natural Product Biosynthesis By Microorganisms And Plants Part C,517

Автор: Hopwood, David A.
Название: Natural Product Biosynthesis By Microorganisms And Plants Part C,517
ISBN: 0124046347 ISBN-13(EAN): 9780124046344
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание: Covers Natural product biosynthesis by microorganisms and plants. This title includes chapters on such topics as metabolic pathways in Aspergillus oryzae, heterologous gene clusters and cyanobacteria as a source of natural products.

Natural Product Biosynthesis By Microorganisms And Plants Part B,516

Автор: Hopwood, David A.
Название: Natural Product Biosynthesis By Microorganisms And Plants Part B,516
ISBN: 0123942918 ISBN-13(EAN): 9780123942913
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание: Continues the legacy of this premier serial by containing quality chapters authored by leaders in the field.

Natural Product Biosynthesis By Microorganisms And Plants, Part A,515

Автор: Hopwood, David A.
Название: Natural Product Biosynthesis By Microorganisms And Plants, Part A,515
ISBN: 012394290X ISBN-13(EAN): 9780123942906
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание: Part of Methods in Enzymology series, this title covers Natural product biosynthesis by microorganisms and plants, it has chapters on such topics as Kinetics of plant sesquiterpene synthases, and plant Type III polyketide synthases.

Complex Enzymes In Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins And Carbohydrates,459

Автор: Hopwood, David A.
Название: Complex Enzymes In Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins And Carbohydrates,459
ISBN: 0123745918 ISBN-13(EAN): 9780123745910
Издательство: Elsevier Science
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Цена: 22738.00 р.
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Описание: Intends to showcase important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. This title covers biosynthesis of Polyketides, Tarpenoids, Aminocoumarins and Crabohydrates.

Complex Enzymes In Microbial Natural Product Biosynthesis, Part A: Overview Articles And Peptides,458

Автор: Hopwood, David A.
Название: Complex Enzymes In Microbial Natural Product Biosynthesis, Part A: Overview Articles And Peptides,458
ISBN: 0123745888 ISBN-13(EAN): 9780123745880
Издательство: Elsevier Science
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Цена: 22738.00 р.
Наличие на складе: Поставка под заказ.

Описание: Intends to showcase the important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. This title covers ribosomally-synthesised and Non-ribosomally-synthesised peptides.

From Biosynthesis to Total Synthesis - Strategies and Tactics for Natural Products

Автор: Zografos
Название: From Biosynthesis to Total Synthesis - Strategies and Tactics for Natural Products
ISBN: 1118751736 ISBN-13(EAN): 9781118751732
Издательство: Wiley
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Цена: 26762.00 р.
Наличие на складе: Поставка под заказ.

Marine Natural Products — Diversity and Biosynthesis

Автор: Paul J. Scheuer; B.J. Baker; C.W.J. Chang; G. Cimi
Название: Marine Natural Products — Diversity and Biosynthesis
ISBN: 3662149273 ISBN-13(EAN): 9783662149270
Издательство: Springer
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Цена: 15372.00 р.
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Описание: 1. B.J. Baker, R.G. Kerr: Biosynthesis of Marine Sterols 2. C.W.J. Chang, P.J. Scheuer: Marine Isocyano Compounds 3. G. Cimino, G. Sodano: Biosynthesis of Secondary Metabolites in Marine Molluscs 4. W.H. Gerwick, D.G. Nagle, P.J. Proteau: Oxylipins from Marine Invertebrates

Biosynthesis, Metabolism and Mode of Action of Invertebrate Hormones

Автор: J. Hoffmann; M. Porchet
Название: Biosynthesis, Metabolism and Mode of Action of Invertebrate Hormones
ISBN: 3642699243 ISBN-13(EAN): 9783642699245
Издательство: Springer
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Цена: 26122.00 р.
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Описание: The neuroendocrine control of reproduction and development of inver- tebrates has a long tradition as an important area of research in France. The reader of this volume is certainly familiar with the significant con- tributions to this field made by such outstanding scientific personalities as J ean-J acques Bounhiol, Jean Panouse, Bernard Possompes, Pierre and Line Joly, Helene Charniaux-Cotton, Maurice Durchon, Manfred Gabe, Guy Echalier, Marie Raabe, and others. It is therefore not surprising that the Centre National de la Recherche Scientifique (CNRS) sponsored, in 1975 and 1983, two major inter- national meetings devoted to this subject. The organizers of the 1975 meeting, which was held in Lille, decided to concentrate on the bio- synthesis, metabolism, and mode of action of the invertebrate hor- mones. To some extent, Professors Durchon and J oly wanted to convey the message that they felt that the period of classical invertebrate endo- crinology had come to an end and that traditional approaches were be- ing replaced by biochemical analyses. How right they were is illustrated by the present volume. Today biochemistry, molecular biology, and analytical chemistry are tools of the invertebrate endocrinologist, who now starts his morning work by homogenizing his worm, mollusc, insect . . . and by extracting DNA, steroids, or peptides.

The Enzymes of Biological Membranes

Автор: Anthony Martonosi
Название: The Enzymes of Biological Membranes
ISBN: 1461294428 ISBN-13(EAN): 9781461294429
Издательство: Springer
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Цена: 15672.00 р.
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Описание: In the first edition of The Enzymes of Biological Membranes, published in four volumes in 1976, we collected the mass of widely scattered information on membrane-linked enzymes and metabolic processes up to about 1975.

Anthocyanins

Автор: Kevin Gould; Kevin M Davies; Chris Winefield
Название: Anthocyanins
ISBN: 0387773347 ISBN-13(EAN): 9780387773346
Издательство: Springer
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Цена: 28734.00 р.
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Описание: There has been an unprecedented expansion of knowledge about anthocyanins pigments. This book covers various aspects of the biosynthesis and function of anthocyanins (and related compounds such as proanthocyanidins) in plants, and their applications in agriculture, food products, and human health.


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