Автор: Amine Kamen, Laura Cervera Название: Bioprocessing of Viral Vaccines ISBN: 1032132116 ISBN-13(EAN): 9781032132112 Издательство: Taylor&Francis Рейтинг: Цена: 22202.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines.
Описание: This book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background information and also tackles animal models in NTD therapeutics research. By bringing together state-of-the-art expert knowledge, the book contributes to the aim of ultimately ending the epidemics of neglected tropical diseases, complying with UN Sustainable Development Goal 3, Health and Well-Being. The volume highlights the activities of the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD pAThogEns), funded by the Medical Research Council in the UK. The four NTDs discussed in the book were selected as these are in the focus of VALIDATE’s research. The book targets scientists and clinicians working on NTDs, as well as all readers with a background in biomedicine and interest in vaccine development. This is an open access book.
Описание: Chapter 1 COVID-19 Vaccines: Between Ethics, Health and Economics 11.1 Introduction 11.2 Development of the COVID-19 Vaccine 11.3 Two Key Issues: Immunity and Contagion 21.4 Vaccine Nationalism 21.5 The COVAX Mechanism 31.6 Compulsory Licensing 31.7 Access to Medicines and Vaccines: A New Player 3 References..........................................................................................................#Chapter 2 Medicines and Intellectual Property: 10 Years of the WHO Global Strategy 72.1 Introduction 72.2 The Background of the IGWG Negotiations 92.3 The IGWG Stakeholders 112.4 The IGWG Process 122.4.1 The First Meeting in Geneva: 4-8 December 2006 122.4.2 Regional Consultations 132.4.3 Second Meeting, 5-10 November 2007 152.4.4 Continuation of the Second Meeting of the IGWG: 28 April to 3 May 2008 152.4.5 Sixty-First World Health Assembly, 24 May 2008 152.5 The Global Strategy and Plan of Action on Public Health, Innovation and Intellectual Property 172.5.1 Main Elements of the 2008 Global Strategy 172.5.2 Additional Mandates of the 2008 Global Strategy 172.5.3 Progress in the Implementation of the GSPOA 182.5.4 The Collaboration of the WHO with other International Organisations 192.6 The WHO Consultative Expert Working Group 202.6.1 A Binding International Convention 202.6.2 The Framework Convention on Tobacco Control 212.7 The Evaluation of the GSPOA 222.8 The Report of the United Nations Secretary-General's High-Level Panel on Access to Medicines 232.9 The Roadmap on Access to Medicines 252.9.1 Background 252.9.2 Regulatory Systems Strengthening 262.9.3 Health Research and Development 262.9.4 Intellectual Property 272.10 Resolution on "Improving the Transparency of Markets for Medicines, Vaccines and other Health-Related Technologies" 272.11 Access to Biotherapeutic Products Including Similar Biotherapeutic Products 292.12 Conclusions 30References 31Chapter 3 Re-thinking Global and Local Manufacturing of Medical Products After COVID-19 333.1 Introduction 333.2 Background: The View of UN Agencies on Pharmaceutical Production in Developing Countries 343.3 COVID-19 "Vaccine Nationalism" 373.4 COVID-19 Global Vaccine Access Facility (COVAX Facility) 423.5 Global Preparedness Monitoring Board 443.6 A COVID-19 Technology Sharing Platform: A Recent UN Initiative 463.7 Concluding Remarks 46References 47Chapter 4 Rethinking R&D for Pharmaceutical Products After the Novel Coronavirus COVID-19 Shock 534.1 Introduction 534.2 Background of the Debate on the R&D Model 544.3 Problems of the R&D Model for Pharmaceutical Products 564.3.1 Lack of Transparency of R&D Costs 564.3.2 Pharmaceutical Innovation Has Significantly Decreased 574.3.3 High Prices Restrict Access 574.3.4 Fragmentation and Lack of Coordination 584.3.5 Waste and Overlap 594.4 A Binding International Convention 594.4.1 Objective and Scope 604.4.2 Possible Main Components 604.5 The Need to Act Fast 614.6 Conclusions and Recommendations 62 References.................
Автор: Elumalai, Preetham Название: Fish Vaccines ISBN: 1032483415 ISBN-13(EAN): 9781032483412 Издательство: Taylor&Francis Рейтинг: Цена: 20671.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Arpagaus Название: Spray Drying of Vaccines ISBN: 3031243226 ISBN-13(EAN): 9783031243226 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Поставка под заказ.
Описание: This book addresses the stabilization of vaccine powders by spray drying and provides an overview of the current state of the art on a laboratory and industrial scale. The book aims to familiarize readers with the advances in vaccine spray drying technology to understand its application potential better. In particular, the book addresses the design of aseptic spray dryers, parameters affecting the spray drying process, sterile powder processing, cleaning procedures, and powder filling. In addition, different drying technologies for the production of dry powder vaccines are compared to discuss the unique capabilities of spray drying as a particle technology for vaccines. Special attention is given to research studies on spray-dried vaccines published over the past 30 years, with key findings from laboratory research to clinical trials. Potential applications of spray-dried vaccines and routes of administration are presented in detail. Finally, an outlook is given on how close the aseptic spray-drying of vaccines is to the market and the challenges that need to be overcome to be commercially successful. The book's target audience is academics, researchers, vaccine developers, industry experts, students, and possibly funders, including government agencies, who are active in the field. In addition, the book is a reference source for those involved in the vaccine formulation and biopharmaceutical processing industry.
Описание: This book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background information and also tackles animal models in NTD therapeutics research. By bringing together state-of-the-art expert knowledge, the book contributes to the aim of ultimately ending the epidemics of neglected tropical diseases, complying with UN Sustainable Development Goal 3, Health and Well-Being. The volume highlights the activities of the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD pAThogEns), funded by the Medical Research Council in the UK. The four NTDs discussed in the book were selected as these are in the focus of VALIDATE’s research. The book targets scientists and clinicians working on NTDs, as well as all readers with a background in biomedicine and interest in vaccine development. This is an open access book.
Автор: Manuel J.T. Carrondo; Bryan Griffiths; Jos? L.P. M Название: Animal Cell Technology ISBN: 0792343212 ISBN-13(EAN): 9780792343219 Издательство: Springer Рейтинг: Цена: 58774.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Contains the proceedings of the 14th Meeting of the European Society for Animal Cell Technology (Vilamoura, Portugal, May 1996) which bring the historical perspective of animal cell technology for the benefit of society. This work covers integration of bioreaction with bioseparation coupled with on-line monitoring to improve protein production.
Автор: Madkour, Loutfy H. Название: Nanoparticle-Based Drug Delivery in Cancer Treatment ISBN: 1032135204 ISBN-13(EAN): 9781032135205 Издательство: Taylor&Francis Рейтинг: Цена: 33686.00 р. Наличие на складе: Поставка под заказ.
Автор: Madkour Loutfy H. Название: RNA Delivery Function for Anticancer Therapeutics ISBN: 1032135166 ISBN-13(EAN): 9781032135168 Издательство: Taylor&Francis Рейтинг: Цена: 28327.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the status of clinical trials related to siRNA-based cancer therapy, as well as the remaining issues that need to be overcome to establish a successful therapy. It, then introduces various promising design strategies of delivery vehicles for stable and targeted siRNA delivery, including the prospects for future design.
Автор: Thomas Название: Vaccine Design ISBN: 1071618865 ISBN-13(EAN): 9781071618868 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 1: Vaccines for Human Diseases aims to be a useful practical guide to researchers to help further their study in this field.
Автор: Skwarczynski, Mariusz Название: Micro and Nanotechnology in Vaccine Development ISBN: 0323399819 ISBN-13(EAN): 9780323399814 Издательство: Elsevier Science Рейтинг: Цена: 21054.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress.
MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles.
Автор: Thomas Название: Vaccine Design ISBN: 1071618946 ISBN-13(EAN): 9781071618943 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides a practical guide providing step-by-step methods and protocols on vaccine development and production. Divided into three volumes, Volume 3: Resources for Vaccine Development guides readers through chapters on vaccine adjuvants, vaccine vectors, production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation, and intellectual property. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 3: Resources for Vaccine Development aims to be a useful practical guide to researchers to help further their study in this field.
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