A History of Genomics across Species, Communities and Projects, Garc?a-Sancho
Автор: Anthony J.F. Griffiths, John Doebley, Catherine Pe Название: An Introduction to Genetic Analysis ISBN: 1319114776 ISBN-13(EAN): 9781319114770 Издательство: Macmillan Learning Рейтинг: Цена: 15244.00 р. Наличие на складе: Нет в наличии.
Описание: The evolution of a classicThe new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level.
Автор: Cornel Mulhardt Название: Molecular Biology and Genomics, ISBN: 0120885468 ISBN-13(EAN): 9780120885466 Издательство: Elsevier Science Рейтинг: Цена: 6772.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.
Автор: Strachan Название: Human Molecular Genetics ISBN: 0815345895 ISBN-13(EAN): 9780815345893 Издательство: Taylor&Francis Рейтинг: Цена: 12095.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.
Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.
Key features:
Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology
Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms
Summary boxes at the end of each chapter provide clear learning points
Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study
Reorganized into five sections for improved access to related topics
Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics
A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.
Описание: A history of how scientists in various fields collaborated from 1920 to 1960 to better understand the solar system, this book, first published in 1996, examines such areas as the origin of comets, the nature of planets, and the significance of impact collisions on Earth`s history.
Описание: At publication date, a free ebook version of this title will be available through Luminos, University of California Press's Open Access publishing program. Visit www.luminosoa.org to learn more.
When China's War of Resistance against Japan began in July 1937, it sparked an immediate health crisis throughout China. In the end, China not only survived the war but emerged from the trauma with a more cohesive population. Intimate Communities argues that women who worked as military and civilian nurses, doctors, and midwives during this turbulent period built the national community, one relationship at a time. In a country with a majority illiterate, agricultural population that could not relate to urban elites' conceptualization of nationalism, these women used their work of healing to create emotional bonds with soldiers and civilians from across the country. These bonds transcended the divides of social class, region, gender, and language.
Автор: Michael Hehenberger, Zhi Xia Название: Our Animal Connection: What Sapiens Can Learn From Other Species ISBN: 9814800481 ISBN-13(EAN): 9789814800488 Издательство: Taylor&Francis Рейтинг: Цена: 9492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book covers the many ways humans benefit from interactions with other living species. By studying animals of all kinds and sizes, from microbial organisms to elephants and whales, we can learn about their adaptations to extreme conditions on planet Earth, about the evolutionary development of specialized capabilities, and about their ways to defend themselves against predators and diseases. We discuss the strengths and weaknesses of Homo Sapiens, and how the study of animals can make us stronger and healthier. To increase our knowledge of genetics, molecular and cell biology, physiology and medicine, we need to study model organisms. To cure human disease, we can learn from animals how they have evolved ways to protect themselves. To improve our human performance, we can study the animal kingdom’s top performers and possibly learn from their successes. Finally, we review genetic engineering techniques that can translate our existing and future animal connections into benefits for human health and performance.
Описание: This open access book offers a comprehensive overview of the history of genomics across three different species and four decades, from the 1980s to the recent past. It takes an inclusive approach in order to capture not only the international initiatives to map and sequence the genomes of various organisms, but also the work of smaller-scale institutions engaged in the mapping and sequencing of yeast, human and pig DNA. In doing so, the authors expand the historiographical lens of genomics from a focus on large-scale projects to other forms of organisation. They show how practices such as genome mapping, sequence assembly and annotation are as essential as DNA sequencing in the history of genomics, and argue that existing depictions of genomics are too closely associated with the Human Genome Project. Exploring the use of genomic tools by biochemists, cell biologists, and medical and agriculturally-oriented geneticists, this book portrays the history of genomics as inseparably entangled with the day-to-day practices and objectives of these communities. The authors also uncover often forgotten actors such as the European Commission, a crucial funder and forger of collaborative networks undertaking genomic projects. In examining historical trajectories across species, communities and projects, the book provides new insights on genomics, its dramatic expansion during the late twentieth-century and its developments in the twenty-first century. Offering the first extensive critical examination of the nature and historicity of reference genomes, this book demonstrates how their affordances and limitations are shaped by the involvement or absence of particular communities in their production.
Автор: Jean C Zenklusen Название: Collaborative Genomics Projects: A Comprehensive Guide ISBN: 0128021438 ISBN-13(EAN): 9780128021439 Издательство: Elsevier Science Рейтинг: Цена: 10441.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "
Collaborative Genomics Projects: A Comprehensive Guide" contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting.
This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types.
As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences. Establishes a framework for managing large-scale genomic research projects involving multiple collaboratorsDescribes lessons learned through TCGA to prepare for potential roadblocksEvaluates policy considerations that are needed to avoid pitfallsRecommends strategies to make project management more efficient
Описание: Periodicals played a vital role in the developments in science and medicine that transformed nineteenth-century Britain. Proliferating from a mere handful to many hundreds of titles, they catered to audiences ranging from gentlemanly members of metropolitan societies to working-class participants in local natural history clubs. In addition to disseminating authorized scientific discovery, they fostered a sense of collective identity among their geographically dispersed and often socially disparate readers by facilitating the reciprocal interchange of ideas and information. As such, they offer privileged access into the workings of scientific communities in the period. The essays in this volume set the historical exploration of the scientific and medical periodicals of the era on a new footing, examining their precise function and role in the making of nineteenth-century science and enhancing our vision of the shifting communities and practices of science in the period. This radical rethinking of the scientific journal offers a new approach to the reconfiguration of the sciences in nineteenth-century Britain and sheds instructive light on contemporary debates about the purpose, practices, and price of scientific journals.
How can people of faith foster love and resilience in our children while building sustainable, diverse communities? That's the big question Ken Whitt answers in light of the many threats looming in our world. Through wisdom he has gleaned from scientists, scholars and lots of real families, Ken shows how God's love is a hopeful compass in our lives. He encourages enjoying stories, songs and explorations of the natural world with children, and closes with "100 Things Families Can Do To Find Hope and Be Love."
Because Ken has years of experience working with multi-generational groups, his book encourages reflections and activities with our families that he knows will be both fun and faithful. The cover of his book illustrates a central story he shares about the wonderment families discover when they look up into the starry night sky with their children.
"Ken Whitt offers care to weary souls in this book. It is not just his words but the spirit that manifests through the words. Ken says that love is at the heart of reality and love is what he gently breathes on us here," Christian ethicist David Gushee, author of Changing Our Mind, writes in the book's Foreword.
"As you read this wise and joyful book, I know you will feel both instructed and delighted, and you will agree that your life has been enriched by adopting Ken Whitt as a literary pastor, mentor and friend," Brian McLaren, best-selling author of more than 20 books, writes in the Preface.
"In extensive dialog with scientists and theologians, Ken shows the delightful and enriching complementarity of faith and science. Both can feed us mentally and emotionally, and both are needed to move us in constructive and creative ways in the face of the global perils we face," writes Daniel Buttry, author of Blessed Are the Peacemakers and the former Global Consultant for Peace and Justice of the American Baptist Churches.
Описание: This book provides a detailed history of theUnited States National Committee on Theoretical and Applied Mechanics(USNC/TAM) of the US National Academies, the relationship between the USNC/TAMand IUTAM, and a review of the many mechanicians who developed the field overtime.
Название: Applying Pharmacogenomics in Therapeutics ISBN: 1466582677 ISBN-13(EAN): 9781466582675 Издательство: Taylor&Francis Рейтинг: Цена: 27562.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare--i.e., personalized medicine.
Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text:
Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care
Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services
Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases
Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics
Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination.
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