Epigenetics, Development, Ecology and Evolution, Vaschetto
Автор: Ferguson, Bradley Название: Ferguson-NUTRITIONAL EPIGENOMICS ISBN: 0128168439 ISBN-13(EAN): 9780128168431 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Поставка под заказ.
Описание:
Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders.
Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease.
Empowers the reader to employ nutritional epigenomics approaches in their own research
Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease
Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies
Автор: Tollefsbol Trygve Название: Epigenetics in Human Disease ISBN: 0128122153 ISBN-13(EAN): 9780128122150 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Поставка под заказ.
Описание: Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, and epigenetic mechanisms of imprinting disorders.
Further sections explore online epigenetic tools and datasets, early-life programming of epigenetics in age-related diseases, the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies.
Автор: Carey Nessa Название: Epigenetics Revolution ISBN: 1848313470 ISBN-13(EAN): 9781848313477 Издательство: TBS/GBS Рейтинг: Цена: 2374.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: At the beginning of this century enormous progress had been made in genetics. The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet.
Автор: Fry, Rebecca Название: Environmental Epigenetics In Toxicology And Public Health ISBN: 0128199687 ISBN-13(EAN): 9780128199688 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Поставка под заказ.
Описание:
Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects.
This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures.
Автор: Kovalchuk, Igor Название: Genome Stability,26 ISBN: 0323856799 ISBN-13(EAN): 9780323856799 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Поставка под заказ.
Описание: With a healthy perspective we can become resilient in ways that not only help us bounce back from stress and tough times, but we can actually deepen in ways which would not have been possible had they not occurred in the first place. The Simple Care of a Hopeful Heart offers a series of brief, accessible lessons in self-care and self-understanding to enhance such possibilities.
Автор: Castelo-Branco, Pedro Название: Histone Modifications In Therapy ISBN: 0128164220 ISBN-13(EAN): 9780128164228 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Поставка под заказ.
Описание:
Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease prevention and treatment. Here, researchers, clinicians and students will discover a thorough, evidence-based discussion of the biology of histones, the diseases engaged by aberrant histone modifications, and pathways with therapeutic potential. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, autoimmune and inflammatory disorders, among others. In relation to these disease types, histone modifications are discussed, both as mechanisms of prevention and possible treatment.
A concluding chapter brings together future perspectives for targeting histone modifications in therapy and next steps in research.
You Are About To Develop An Insider Understanding Of Epigenetics, Including Their Relationship With The DNA, Environmental Factors, Human Development And Evolution; Their Role In Human Mental And Physical Health, Including Their Use In The Treating Of Different Conditions And Diseases Along With The Most Current Epigenetic Practices And Research
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More precisely, you will learn:
- What epigenetics are and their role in developmental psychology
- The influence of epigenetics at the molecular level and the impact of DNA damage in epigenetic change
- How epigenetics are studied
- The functions and consequences of epigenetics, and their specific benefits in mindfulness training, healthy eating and physical activity
- How genes control the growth and division of cells
- The role of epigenetic therapy in diabetic retinopathy, emotional disorders, cardiac dysfunction, cancer and schizophrenia and many more
- How epigenetic modifications are used in cancer treatment, and plant and animal evolution
- How epigenetic mechanisms are used in processes including human adaptation, memory formation, growth and infant neuro-behavior.
- How epigenetic mechanisms are used in maternal care
- How environmental chemical exposures affect epigenetics
- The role of epigenetics in neurodegenerative diseases, drug formation, human development, the development of Hox genes and many more
- The role of environmental exposures in pathophysiology of IPF
- Modulation of epigenetic marks by environmental exposures
- How epigenetic regulation affects the immune system
...And so much more
So if you've been exposed to the concept of epigenetics as a novel way of understanding disorders, inheritance and evolution and wondered what it's really all about and how it's related with environmental exposure and different therapy practices, this book is all you need
Автор: Cacabelos, Ram?n Название: Pharmacoepigenetics ISBN: 0128139390 ISBN-13(EAN): 9780128139394 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development.
Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.
Fully examines the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, treatment, current epigenetic drugs and the application of epigenetic procedures in drug development
Features chapter contributions from leading international researchers in academia, clinical settings and the pharmaceutical industry
Instructs researchers, students and clinicians on how to better interpret and employ pharmacoepigenetics in drug development, efficiency and safety
Provides a balanced and objective discussion of the future of pharmacoepigenetics and its crucial role in precision medicine
Автор: Tollefsbol, Trygve Название: Epigenetics And Reproductive Health ISBN: 0128197536 ISBN-13(EAN): 9780128197530 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Поставка под заказ.
Описание:
Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms.
Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics.
Автор: C.D. Rollo Название: Phenotypes ISBN: 0412410303 ISBN-13(EAN): 9780412410307 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Incorporates modern molecular knowledge of genes into an evolutionary framework, stressing the importance of genomic integration in the evolution of multicellular phenotypes. This text reinterprets epigenetics, the evolution of sex and the evolution of longevity assurance systems.
Автор: Vaschetto Название: Epigenetics, Development, Ecology and Evolution ISBN: 3031137736 ISBN-13(EAN): 9783031137730 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetic modifications comprise heritable gene expression changes that occur without alteration of the DNA sequence and 'co-act' with genetic factors to shape development processes and evolutionary trajectories. Multicellular organisms receive different types of environmental stimuli/stresses that trigger epigenetic modifications during development. These environmentally driven mechanisms represent an underlying cause of phenotypic diversity, especially in metazoans. This book aims to present some of the latest epigenetic insights into the development of metazoans (including humans) as an intersection between their ecology and evolution.
Автор: Oldroyd, Benjamin Название: Beyond dna ISBN: 0522878865 ISBN-13(EAN): 9780522878868 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 1880.00 р. Наличие на складе: Нет в наличии.
Описание: Beyond DNA is a journey through uncharted territory, advancing new ways of thinking about evolution and adaptation. For nearly a hundred years evolutionary biologists have understood that evolution proceeds by substituting better genes for less good ones. But consensus is growing that this is not the whole story: geneticists are now revealing that spores, sperm, pollen and ova are packed with personalised genetic information that plays an important role in offspring development and has lifelong effects. This epigenetic - or 'extra-genetic '- inheritance therefore makes significant contributions to evolutionary processes. In this highly accessible book, packed with instructive examples, Benjamin Oldroyd explains how a greater appreciation of the role of epigenetics is helping to solve a multitude of previously intractable problems in evolutionary biology - puzzles as varied as why invasive plants and animals can rapidly adapt to changes in their environment, how worker bees and queen bees can develop from the same egg, and why cancer becomes more common as we age. Beyond DNA concisely explains the mechanisms that underlie epigenetics, shows how epigenetic processes can lead to adaptation, and speculates on meaty issues such as the role that epigenetics plays in human health and happiness.
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