Epigenetics, Development, Ecology and Evolution, Vaschetto

Автор: Ferguson, Bradley
Название: Ferguson-NUTRITIONAL EPIGENOMICS
ISBN: 0128168439 ISBN-13(EAN): 9780128168431
Издательство: Elsevier Science
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Цена: 26444.00 р.
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Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders.

Автор: Tollefsbol Trygve
Название: Epigenetics in Human Disease
ISBN: 0128122153 ISBN-13(EAN): 9780128122150
Издательство: Elsevier Science
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Цена: 23075.00 р.
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Описание: Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, and epigenetic mechanisms of imprinting disorders.

Further sections explore online epigenetic tools and datasets, early-life programming of epigenetics in age-related diseases, the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies.

Автор: Carey Nessa
Название: Epigenetics Revolution
ISBN: 1848313470 ISBN-13(EAN): 9781848313477
Издательство: TBS/GBS
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Цена: от 701.00 р.
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Описание: At the beginning of this century enormous progress had been made in genetics. The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet.

Автор: Oldroyd, Benjamin
Название: Beyond dna
ISBN: 0522878865 ISBN-13(EAN): 9780522878868
Издательство: Mare Nostrum (Eurospan)
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Цена: 1880.00 р.
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Описание: Beyond DNA is a journey through uncharted territory, advancing new ways of thinking about evolution and adaptation. For nearly a hundred years evolutionary biologists have understood that evolution proceeds by substituting better genes for less good ones. But consensus is growing that this is not the whole story: geneticists are now revealing that spores, sperm, pollen and ova are packed with personalised genetic information that plays an important role in offspring development and has lifelong effects. This epigenetic - or 'extra-genetic '- inheritance therefore makes significant contributions to evolutionary processes. In this highly accessible book, packed with instructive examples, Benjamin Oldroyd explains how a greater appreciation of the role of epigenetics is helping to solve a multitude of previously intractable problems in evolutionary biology - puzzles as varied as why invasive plants and animals can rapidly adapt to changes in their environment, how worker bees and queen bees can develop from the same egg, and why cancer becomes more common as we age. Beyond DNA concisely explains the mechanisms that underlie epigenetics, shows how epigenetic processes can lead to adaptation, and speculates on meaty issues such as the role that epigenetics plays in human health and happiness.

Автор: Mai Antonello
Название: Chemical Epigenetics
ISBN: 3030429849 ISBN-13(EAN): 9783030429843
Издательство: Springer
Цена: 27950.00 р.
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Описание: This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology.

Автор: Fry, Rebecca
Название: Environmental Epigenetics In Toxicology And Public Health
ISBN: 0128199687 ISBN-13(EAN): 9780128199688
Издательство: Elsevier Science
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Цена: 24423.00 р.
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Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects.

Автор: Spillane Charles, McKeown Peter
Название: Plant Epigenetics and Epigenomics: Methods and Protocols
ISBN: 1071601784 ISBN-13(EAN): 9781071601785
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This second edition volume expands on the previous edition with a look at the latest techniques in plant epigenetics and epigenomic research. Chapters in this book cover topics such as whole genome methylome analysis; analysis of DNA methylation; chromatin analysis of metabolic gene clusters in plants; plant epigenetic stress memory induced by drought; small non-coding RNA analysis in seeds of forest tree species; and a discussion on epigenetics inheritance in plants. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Plant Epigenetics and Epigenomics: Methods and Protocols, Second Edition is a valuable resource for both novice and expert researchers, and aims to advance this field of study by paving the way for integrating epigenetic mechanisms into models of plant function during development and evolution.

Автор: Kovalchuk, Igor
Название: Genome Stability,26
ISBN: 0323856799 ISBN-13(EAN): 9780323856799
Издательство: Elsevier Science
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Цена: 26444.00 р.
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Описание: With a healthy perspective we can become resilient in ways that not only help us bounce back from stress and tough times, but we can actually deepen in ways which would not have been possible had they not occurred in the first place. The Simple Care of a Hopeful Heart offers a series of brief, accessible lessons in self-care and self-understanding to enhance such possibilities.

Автор: Castelo-Branco, Pedro
Название: Histone Modifications In Therapy
ISBN: 0128164220 ISBN-13(EAN): 9780128164228
Издательство: Elsevier Science
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Цена: 24423.00 р.
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Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease prevention and treatment. Here, researchers, clinicians and students will discover a thorough, evidence-based discussion of the biology of histones, the diseases engaged by aberrant histone modifications, and pathways with therapeutic potential. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, autoimmune and inflammatory disorders, among others. In relation to these disease types, histone modifications are discussed, both as mechanisms of prevention and possible treatment.

Автор: Patel
Название: Handbook of Nutrition, Diet, and Epigenetics
ISBN: 3319555294 ISBN-13(EAN): 9783319555294
Издательство: Springer
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Цена: 73930.00 р.
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Описание: This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.

Автор: Lucchesi John
Название: Epigenetics, Nuclear Organization & Gene Function
ISBN: 0198831218 ISBN-13(EAN): 9780198831211
Издательство: Oxford Academ
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Цена: 8237.00 р.
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Описание: Provides a framework to understand the basis of epigenetic regulation and to appreciate both its derivation from genetics and interdependence with genetic mechanisms. It further aims to highlight the role of the three-dimensional organization of the genetic material itself and its distribution in a functionally compartmentalized nucleus.

Автор: Gupta
Название: Targeting Epigenetics in Inflammatory Lung Diseases
ISBN: 9819947790 ISBN-13(EAN): 9789819947799
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation?related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.