Environmental Epigenetics In Toxicology And Public Health, Fry, Rebecca
Автор: Johannes Backs, Timothy McKinsey Название: Epigenetics in Cardiac Disease ISBN: 3319414550 ISBN-13(EAN): 9783319414553 Издательство: Springer Рейтинг: Цена: 14673.00 р. 20962.00-30% Наличие на складе: Есть (1 шт.) Описание: This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.
Автор: Tollefsbol Trygve Название: Epigenetics in Human Disease ISBN: 0128122153 ISBN-13(EAN): 9780128122150 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Нет в наличии.
Описание: Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, and epigenetic mechanisms of imprinting disorders.
Further sections explore online epigenetic tools and datasets, early-life programming of epigenetics in age-related diseases, the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies.
Автор: L. Joseph Su; Tung-chin Chiang Название: Environmental Epigenetics ISBN: 1447172582 ISBN-13(EAN): 9781447172581 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.
Автор: L. Joseph Su; Tung-chin Chiang Название: Environmental Epigenetics ISBN: 1447166779 ISBN-13(EAN): 9781447166771 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: What is Epigenetics.- Epidemiology of environment and health.- Technologies in measuring epigenetics.- Epigenetic changes in hormone related disease.- Epigenetic effects of environmental chemicals bisphenol a and phthalates.- Environmental epigenetics: a role in endocrine diseases?.- Pregnancy exposures determine risk of breast cancer in multiple generations of offspring.- Environmental epigenetics and obesity - evidences from animal to epidemiologic studies.- Environmental toxicants, epigenetics and cancer.- Aging, genes, environment and epigenetics.- Epigenetics: The link between nature and nurture.- Gene-Environment Interactions in Human Health.- Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.- Conclusions: Lessons from epigenetic research: the impact of environmental stress can be accumulated and resulted in diverse outcome.
Автор: Drew Augustus Название: Epigenetics and Human Health ISBN: 1632416522 ISBN-13(EAN): 9781632416520 Издательство: Неизвестно Рейтинг: Цена: 23335.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Burdge Graham, Lillycrop Karen Название: Nutrition, Epigenetics and Health ISBN: 9813143304 ISBN-13(EAN): 9789813143302 Издательство: World Scientific Publishing Цена: 13781.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.
Описание: This stimulating volume addresses vital questions about gene/environment interactions as they affect cell health from the prenatal period through later life. Beginning with a tour of epigenetic processes in the human body, the book assembles current theoretical and empirical developments across the discipline, among them transgenerational epigenetic inheritance, the effects of maternal nutrition on epigenetic change, and possible links between epigenetics and childhood obesity. Public health and policy aspects of the field are discussed in depth, with the understanding that much can be done to improve our epigenetic health as a species. And in this vein, contributors consider future possibilities, such as the reprogramming of genes to reverse cancer and other diseases. Included in the coverage: The role of environmental epigenetics in perinatal and neonatal developmentThe epigenetic biomarker ?H2AX: from bench science to clinical trialsWhat’s the risk? Dental amalgam, mercury exposure, and human health risks throughout the lifespanPost-traumatic stress disorder: neurological, genetic, and epigenetic basesChildren’s exposure to alcohol, tobacco, and drugs: long-term outcomesEthical implications of epigenetics Epigenetics, the Environment, and Children’s Health Across Lifespans brings real-world knowledge and applications of this increasingly important field to public health practitioners, maternal and child health researchers, and environmental health experts.
Описание: This timely book critically examines the capabilities and limitations of new areas of biology, especially epigenetics and neuroscience, that are used as powerful arguments for developing social policy in a particular direction, exploring their implications for policy and practice.
Описание: For as much as we know about DNA and gene expression, many more mysteries remain to be solved. Epigenetics and epigenomics seek to study heritable modifications in gene expression that do not involve underlying DNA sequences to further human health changes. Examining the Causal Relationship Between Genes, Epigenetics, and Human Health provides innovative research methods and applications of chemical activation or deactivation of genes without altering the original DNA sequence. While highlighting topics including gene expression, personalized medicine, and public policy, this book is ideal for researchers, geneticists, biologists, medical professionals, students, and academics seeking current research on the expanding fields of genomics, epigenomics, proteomics, pharmacogenomics, and genome-wide association studies.
Автор: Tollefsbol, Trygve Название: Epigenetics And Reproductive Health ISBN: 0128197536 ISBN-13(EAN): 9780128197530 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Нет в наличии.
Описание:
Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms.
Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics.
This stimulating volume addresses vital questions about gene/environment interactions as they affect cell health from the prenatal period through later life. Beginning with a tour of epigenetic processes in the human body, the book assembles current theoretical and empirical developments across the discipline, among them transgenerational epigenetic inheritance, the effects of maternal nutrition on epigenetic change, and possible links between epigenetics and childhood obesity. Public health and policy aspects of the field are discussed in depth, with the understanding that much can be done to improve our epigenetic health as a species. And in this vein, contributors consider future possibilities, such as the reprogramming of genes to reverse cancer and other diseases.
Included in the coverage:
The role of environmental epigenetics in perinatal and neonatal development
The epigenetic biomarker γH2AX: from bench science to clinical trials
What's the risk? Dental amalgam, mercury exposure, and human health risks throughout the lifespan
Post-traumatic stress disorder: neurological, genetic, and epigenetic bases
Children's exposure to alcohol, tobacco, and drugs: long-term outcomes
Ethical implications of epigenetics
Epigenetics, the Environment, and Children's Health Across Lifespans brings real-world knowledge and applications of this increasingly important field to public health practitioners, maternal and child health researchers, and environmental health experts.
Автор: Igor Kovalchuk; Franz J. Zemp Название: Plant Epigenetics ISBN: 1607616459 ISBN-13(EAN): 9781607616450 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetics is one of the most popular and quickly evolving fields of modern science. In this book, expert researchers explore the most recent developments, examining in great detail the contribution of epigenetic regulation to cell function in plants.
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