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The Epigenetics of Autoimmunity, Tollefsbol, Trygve


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Автор: Tollefsbol, Trygve
Название:  The Epigenetics of Autoimmunity
Перевод названия: Тригве Толлефсбол: Эпигенетика аутоиммунной системы
ISBN: 9780128099124
Издательство: Elsevier Science
Классификация:


ISBN-10: 0128099127
Обложка/Формат: Hardback
Страницы: 464
Вес: 1.09 кг.
Дата издания: 01.08.2018
Серия: Translational epigenetics
Язык: English
Размер: 229 x 152
Читательская аудитория: Professional & vocational
Основная тема: Immunology
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание: The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. . To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sj?grens syndrome (pSS) and autoimmune thyroid diseases (AITDs). . These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.


Vaccines and Autoimmunity

Автор: Yehuda Shoenfeld,Nancy Agmon–Levin
Название: Vaccines and Autoimmunity
ISBN: 1118663438 ISBN-13(EAN): 9781118663431
Издательство: Wiley
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Цена: 22485.00 р.
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Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.

Medical Epigenetics

Автор: Trygve Tollefsbol
Название: Medical Epigenetics
ISBN: 0128032391 ISBN-13(EAN): 9780128032398
Издательство: Elsevier Science
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Цена: 22696.00 р.
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Описание: "

Medical Epigenetics" is an inclusive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic disease that affect these systems, and modes of treating epigenetic-based disorders and diseases. This book provides stand-alone coverage of all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics.

The expansion of the field of epigenetics has brought a wealth of information with respect to variations in phenotypes that are heritable. In addition, many advances have emerged that have shown epigenetic aberrations as central to a number of diseases and disorders that were previously thought to be manifested primarily through genetic factors. Along with the remarkable studies that have been made in our understanding of epigenetic-based diseases and disorders has come new information that allows treatments that target these many epigenetic aberrations. "Medical Epigenetics" brings all of this knowledge together to comprehensively review the state of medical epigenetics in one defining volume.

The basic design of "Medical Epigenetics" is to lead the reader from the fundamental mechanisms of epigenetics as they apply to humans through approaches for treating epigenetic-based diseases. This book begins with the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics. "Medical Epigenetics" closes with a chapter on future prospects in medical epigenetics. This book is by far the most complete book in the area of applied epigenetics.
Focuses on practical and applied aspects of medical epigeneticsIncludes peer-reviewed chapters with up-to-date coverage of emerging topics in medical epigenetics by leading expertsAppeals to those interested in fundamental epigenetics and inheritance, as well as those with more clinical interests including practicing physicians and other health care professionalsCovers the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics

Current Concepts in Autoimmunity and Chronic Inflammation

Автор: Andreas Radbruch; Peter E. Lipsky
Название: Current Concepts in Autoimmunity and Chronic Inflammation
ISBN: 364206745X ISBN-13(EAN): 9783642067457
Издательство: Springer
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Цена: 32004.00 р.
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Описание: In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions.

The Impact of Biotechnology on Autoimmunity

Автор: A.G. Dalgleish; A. Albertini; Rodolfo Paoletti
Название: The Impact of Biotechnology on Autoimmunity
ISBN: 0792327241 ISBN-13(EAN): 9780792327240
Издательство: Springer
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Цена: 27951.00 р.
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Описание: The association with infectious diseases and autoimmunity is comprehensively covered by David Isenberg who reviews major issues, such as the association of autoantibodies appearing after infectious disease and antibacterial antibodies associated with autoimmune disease.

Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity

Автор: C. Jane Welsh; Mary Meagher; Esther Sternberg
Название: Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
ISBN: 1489997237 ISBN-13(EAN): 9781489997234
Издательство: Springer
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Цена: 18284.00 р.
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Описание: This book provides a lucid summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense.

Molecular and Cell Biology of Autoantibodies and Autoimmunity. Abstracts

Автор: Ekkehard K.F. Bautz; Joachim R. Kalden; Mitsuo Hom
Название: Molecular and Cell Biology of Autoantibodies and Autoimmunity. Abstracts
ISBN: 3540514368 ISBN-13(EAN): 9783540514367
Издательство: Springer
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Цена: 12157.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

The Impact of Biotechnology on Autoimmunity

Автор: A.G. Dalgleish; A. Albertini; Rodolfo Paoletti
Название: The Impact of Biotechnology on Autoimmunity
ISBN: 9401044848 ISBN-13(EAN): 9789401044844
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The association with infectious diseases and autoimmunity is comprehensively covered by David Isenberg who reviews major issues, such as the association of autoantibodies appearing after infectious disease and antibacterial antibodies associated with autoimmune disease.

Apoptosis and Autoimmunity

Автор: Kalden
Название: Apoptosis and Autoimmunity
ISBN: 3527304428 ISBN-13(EAN): 9783527304424
Издательство: Wiley
Цена: 18216.00 р.
Наличие на складе: Поставка под заказ.

Описание: This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases.
It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.

Autoimmunity

Автор: Andrzej G?rski; Hubert Krotkiewski; Michal Zimecki
Название: Autoimmunity
ISBN: 1402000375 ISBN-13(EAN): 9781402000379
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Presents a review of the mechanisms underlying the phenomena of autoimmunity. This book presents concepts in the fundamentals and treatment of autoimmune disorders. It opposes the dogma that autoimmune disorders should be treated with immunosuppressors, and postulates rather the activation of the immune system.

Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity

Автор: C. Jane Welsh; Mary Meagher; Esther Sternberg
Название: Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
ISBN: 0387314113 ISBN-13(EAN): 9780387314112
Издательство: Springer
Рейтинг:
Цена: 22203.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides a lucid summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense.

Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity

Автор: Akihiko Yoshimura
Название: Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity
ISBN: 3319689282 ISBN-13(EAN): 9783319689289
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Further, the volume examines other agents, a number of cells, receptors and signaling molecules, that are also involved in the regulation of T-cell activation and extends the concept of immune checkpoints to "molecules and cells that negatively regulate T-cell activation".


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