Epigenetics, the Environment, and Children`s Health Across Lifespans, David Hollar

Автор: Johannes Backs, Timothy McKinsey
Название: Epigenetics in Cardiac Disease
ISBN: 3319414550 ISBN-13(EAN): 9783319414553
Издательство: Springer
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Описание: This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.

Автор: Tollefsbol, Trygve
Название: The Epigenetics of Autoimmunity
ISBN: 0128099127 ISBN-13(EAN): 9780128099124
Издательство: Elsevier Science
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Цена: 23917.00 р.
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Описание: The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. . To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sj?gren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). . These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.

Автор: Trygve Tollefsbol
Название: Medical Epigenetics
ISBN: 0128032391 ISBN-13(EAN): 9780128032398
Издательство: Elsevier Science
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Описание: "

Medical Epigenetics" is an inclusive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic disease that affect these systems, and modes of treating epigenetic-based disorders and diseases. This book provides stand-alone coverage of all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics.

The expansion of the field of epigenetics has brought a wealth of information with respect to variations in phenotypes that are heritable. In addition, many advances have emerged that have shown epigenetic aberrations as central to a number of diseases and disorders that were previously thought to be manifested primarily through genetic factors. Along with the remarkable studies that have been made in our understanding of epigenetic-based diseases and disorders has come new information that allows treatments that target these many epigenetic aberrations. "Medical Epigenetics" brings all of this knowledge together to comprehensively review the state of medical epigenetics in one defining volume.

The basic design of "Medical Epigenetics" is to lead the reader from the fundamental mechanisms of epigenetics as they apply to humans through approaches for treating epigenetic-based diseases. This book begins with the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics. "Medical Epigenetics" closes with a chapter on future prospects in medical epigenetics. This book is by far the most complete book in the area of applied epigenetics.
Focuses on practical and applied aspects of medical epigeneticsIncludes peer-reviewed chapters with up-to-date coverage of emerging topics in medical epigenetics by leading expertsAppeals to those interested in fundamental epigenetics and inheritance, as well as those with more clinical interests including practicing physicians and other health care professionalsCovers the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics

Автор: Patel
Название: Handbook of Nutrition, Diet, and Epigenetics
ISBN: 3319555294 ISBN-13(EAN): 9783319555294
Издательство: Springer
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Цена: 73930.00 р.
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Описание: This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.

Автор: Trygve O. Tollefsbol
Название: Epigenetics of Aging
ISBN: 1489983104 ISBN-13(EAN): 9781489983107
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This seminal work covers the impact of epigenetics on aging, the epigenetics of age-related diseases, and future directions and perspectives on the epigenetics of aging. It covers the most recent advances that impact the longevity of living organisms.

Автор: Arturas Petronis; Jonathan Mill
Название: Brain, Behavior and Epigenetics
ISBN: 3642268323 ISBN-13(EAN): 9783642268328
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Epigenetics, once believed stable after development, has been found to occur in fully differentiated, post-mitotic central nervous system cells in response to environmental signals. This book explores the role of epigenetic risk factors in complex diseases.

Автор: Walter Doerfler; Petra B?hm
Название: Epigenetics - A Different Way of Looking at Genetics
ISBN: 3319271849 ISBN-13(EAN): 9783319271842
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This book presents epigenetics research as a new way of looking at genetics. Topics range from basic epigenetics mechanisms to development of cells and organisms and the biological basis of diseases. In addition the book focuses on immunology and the role of viruses in epigenetics.

Автор: Trygve O. Tollefsbol
Название: Epigenetics Protocols
ISBN: 149396187X ISBN-13(EAN): 9781493961870
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Focusing on the two broad areas of epigenetics, DNA methylation and chromatin modifications, this book highlights select techniques that have been mainstays in the field. It also covers methods especially relevant to extant discoveries in epigenetics.

Автор: Drew Augustus
Название: Clinical Epigenetics
ISBN: 1632426994 ISBN-13(EAN): 9781632426994
Издательство: Неизвестно
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Цена: 23335.00 р.
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Автор: Drew Augustus
Название: Epigenetics and Human Health
ISBN: 1632416522 ISBN-13(EAN): 9781632416520
Издательство: Неизвестно
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Цена: 23335.00 р.
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Автор: L. Joseph Su; Tung-chin Chiang
Название: Environmental Epigenetics
ISBN: 1447166779 ISBN-13(EAN): 9781447166771
Издательство: Springer
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Цена: 23757.00 р.
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Описание: What is Epigenetics.- Epidemiology of environment and health.- Technologies in measuring epigenetics.- Epigenetic changes in hormone related disease.- Epigenetic effects of environmental chemicals bisphenol a and phthalates.- Environmental epigenetics: a role in endocrine diseases?.- Pregnancy exposures determine risk of breast cancer in multiple generations of offspring.- Environmental epigenetics and obesity - evidences from animal to epidemiologic studies.- Environmental toxicants, epigenetics and cancer.- Aging, genes, environment and epigenetics.- Epigenetics: The link between nature and nurture.- Gene-Environment Interactions in Human Health.- Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.- Conclusions: Lessons from epigenetic research: the impact of environmental stress can be accumulated and resulted in diverse outcome.

Автор: Francis Richard C.
Название: Epigenetics: How Environment Shapes Our Genes
ISBN: 039334228X ISBN-13(EAN): 9780393342284
Издательство: Wiley
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Цена: 2058.00 р.
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Описание: Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics.