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Introduction to Toxicological Screening Methods and Good Laboratory Practice, Chidambaram


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Цена: 20962.00р.
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Автор: Chidambaram
Название:  Introduction to Toxicological Screening Methods and Good Laboratory Practice
ISBN: 9789811660948
Издательство: Springer
Классификация:

ISBN-10: 9811660948
Обложка/Формат: Soft cover
Страницы: 189
Вес: 0.33 кг.
Дата издания: 28.02.2023
Язык: English
Издание: 1st ed. 2022
Иллюстрации: 1 illustrations, black and white; xx, 189 p. 1 illus.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.
Дополнительное описание: Chapter 1. Introduction to Toxicology.- Chapter 2. Laboratory Animal models.- Chapter 3. Toxicology Screening Methods.- Chapter 4. Toxicokinetics.- Chapter 5. Safety Pharmacology.- Chapter 6. Good Laboratory Practice.



Masked Mycotoxins in Food: Formation, Occurrence and Toxicological Relevance

Автор: Dall`asta Chiara, Berthiller Franz
Название: Masked Mycotoxins in Food: Formation, Occurrence and Toxicological Relevance
ISBN: 1849739722 ISBN-13(EAN): 9781849739726
Издательство: Royal Society of Chemistry
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Цена: 31469.00 р.
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Описание: The first book to cover this fast developing field, Masked Mycotoxins in Food will provide a full overview of the issues relating to the toxicology of masked mycotoxins present in food products.

Toxicological Risk Assessment for Beginners

Название: Toxicological Risk Assessment for Beginners
ISBN: 3319127500 ISBN-13(EAN): 9783319127507
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypothetical case studies. Toxicological Risk Assessment for Beginners aims not to create an expert, but rather to provide readers with their first understanding of the risk assessment topic. This book was designed with the student in mind. We simplify a complex process for beginners and balance theory with practical aspects, but remain fluid enough to increase difficulty with case studies. By incorporating an action based, step by step approach to learning the risk assessment process, this book provides its readers with an elementary understanding of how the risk assessment process is initiated, developed and finished, making it a valuable guide for graduate students, post-doctoral fellows and early career scientists in industry.

Introduction to Toxicological Screening Methods and Good Laboratory Practice

Автор: Chidambaram Saravana Babu, Essa M. Mohamed, Qoronfleh M. Walid
Название: Introduction to Toxicological Screening Methods and Good Laboratory Practice
ISBN: 9811660913 ISBN-13(EAN): 9789811660917
Издательство: Springer
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Цена: 20962.00 р.
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Описание:

A. Introduction to Preclinical Toxicology

1. Pharmaceutical products- Regulatory requirements and guidelines

2. Agrochemicals/Pesticides- Regulatory requirements and guidelines

B. Infrastructure

3. Animal/ in vivo facility - Design, utilities, equipment, animals, breeding/stock maintaining/husbandry

4. Procedure, studies, standard operating procedure and guideline for Animal/ in vivo facility

5. In vitro facility - Design, utilities, equipment, cell line maintaining procedure, studies, standard operating procedure and guideline

6. Maintenance and utility area for in vitro facility

7. Design, utilities, equipment maintenance and guidelines for in vitro facility

C. Good laboratory practices (GLP) requirements

8. Test Facility Management

9. Responsibilities, qualification and training

10. Study Directors/Study personnel

11. Responsibilities, qualification and training

D. Test item control office (TICO)

12. Design, utilities, equipment maintenance and guideline

13. Responsibilities, qualification and training

E. Quality Assurance Unit (QAU)

14. Responsibilities, qualification and training

15. Archiving information

16. Design, utilities, equipment maintenance and guideline

17. Responsibilities, qualification and training


Alternative Toxicological Methods

Автор: Salem, Harry
Название: Alternative Toxicological Methods
ISBN: 084931528X ISBN-13(EAN): 9780849315282
Издательство: Taylor&Francis
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Цена: 29093.00 р.
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Clinical Toxicological Analysis: Procedures, Results, Interpretation, 2 Volume Set

Автор: K?lpmann
Название: Clinical Toxicological Analysis: Procedures, Results, Interpretation, 2 Volume Set
ISBN: 3527318909 ISBN-13(EAN): 9783527318902
Издательство: Wiley
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Цена: 48779.00 р.
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Описание: A unique handbook for the laboratory toxicologist that shows how analysis may be improved by standardization and by using quantitative methods. Covers all important classes of toxic substances and contains abundant protocols, data tables and reference measurements.

Toxicological evaluation of electronic nicotine delivery products

Название: Toxicological evaluation of electronic nicotine delivery products
ISBN: 0128204907 ISBN-13(EAN): 9780128204900
Издательство: Elsevier Science
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Цена: 16161.00 р.
Наличие на складе: Поставка под заказ.

Описание: Collins Explore English is a 6-level course which provides full coverage of the Cambridge Primary English as a Second Language curriculum framework (0057) from 2020. With a magazine-style Student`s Resource Book, comprehensive Student`s Coursebook, and supportive Teacher`s Guide, it offers clear progression within and across levels.

Environmental Risk Assessment

Автор: Simon
Название: Environmental Risk Assessment
ISBN: 1138033839 ISBN-13(EAN): 9781138033832
Издательство: Taylor&Francis
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Цена: 9492.00 р.
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Описание:

The purpose of risk assessment is to support science-based decisions about how to solve complex societal problems. The problems we face in the twenty-first century have many social, political, and technical complexities. Environmental risk assessment in particular is of increasing importance as a means of seeking to address the potential effects of chemicals in the environment in both the developed and developing world.

Environmental Risk Assessment: A Toxicological Approach examines various aspects of problem formulation, exposure, toxicity, and risk characterization that apply to both human health and ecological risk assessment. The book is aimed at the next generation of risk assessors and students who need to know more about developing, conducting, and interpreting risk assessments. It delivers a comprehensive view of the field, complete with sufficient background to enable readers to probe for themselves the science underlying the key issues in environmental risk. Written in an engaging and lively style by a highly experienced risk assessment practitioner, the text:

  • Introduces the science of risk assessment-past, present, and future
  • Covers problem formation and the development of exposure factors
  • Explains how human epidemiology and animal testing data are used to determine toxicity criteria
  • Provides environmental sampling data for conducting practice risk assessments
  • Examines the use of in vitro and 'omics methods for toxicity testing
  • Describes the political and social aspects of science-based decisions in the twenty-first century
  • Includes fully worked examples, case studies, discussion questions, and links to legislative hearings

Readers of this volume will not only learn how to execute site-specific human health and ecological risk assessments but also gain a greater understanding of how science is used in deciding environmental regulations.

Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances

Автор: Jamie C. DeWitt
Название: Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances
ISBN: 3319155172 ISBN-13(EAN): 9783319155173
Издательство: Springer
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Цена: 22203.00 р.
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Описание: This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms.

Toxicological Effects of Veterinary Medicinal Products in Humans: Volume 2

Автор: Woodward Kevin
Название: Toxicological Effects of Veterinary Medicinal Products in Humans: Volume 2
ISBN: 1849736847 ISBN-13(EAN): 9781849736848
Издательство: Royal Society of Chemistry
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Цена: 32523.00 р.
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Описание: Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans.

Toxicological Effects of Veterinary Medicinal Products in Humans: Complete Set

Автор: Woodward Kevin
Название: Toxicological Effects of Veterinary Medicinal Products in Humans: Complete Set
ISBN: 1849736855 ISBN-13(EAN): 9781849736855
Издательство: Royal Society of Chemistry
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Цена: 63360.00 р.
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Описание: Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans.

Toxicological Risk Assessment And Multi-System Health Impacts From Exposure

Автор: Tsatsakis, Aristidis M.
Название: Toxicological Risk Assessment And Multi-System Health Impacts From Exposure
ISBN: 0323852157 ISBN-13(EAN): 9780323852159
Издательство: Elsevier Science
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Цена: 23075.00 р.
Наличие на складе: Поставка под заказ.

Описание:

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure highlights emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic and epigenetic effects of long-term exposure. It examines how combined exposures to nanomaterials, metals, pharmaceuticals, multi-frequency radiation, dietary mycotoxins and pesticides accelerate ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment.

Toxicological Chemistry and Biochemistry . 3 ed

Автор: Stanley E. Manahan
Название: Toxicological Chemistry and Biochemistry . 3 ed
ISBN: 1566706181 ISBN-13(EAN): 9781566706186
Издательство: Taylor&Francis
Рейтинг:
Цена: 29093.00 р.
Наличие на складе: Поставка под заказ.

Описание: Bridging the gap between toxicology and chemistry, this book explores the role of genetics in determining individual susceptibilities to various toxicants. It provides a discussion of the interactions between environmental chemicals and living systems. It provides review questions and references at the end of each chapter.


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