Calcium In Living Cells,99, Whitaker, Michael

Автор: Ole H. Petersen
Название: Measuring Calcium and Calmodulin Inside and Outside Cells
ISBN: 3642477372 ISBN-13(EAN): 9783642477379
Издательство: Springer
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Цена: 16979.00 р.
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Описание: The study of signal transduction mechanisms has become one of the most important branches of biomedical science, indispensable to understanding the normal actions of hormones, neurotransmitters and other extracellular signaling molecules as well as many pathophysiological processes, including inflammation and cancer.

Автор: Yong-Xiao Wang
Название: Calcium Signaling In Airway Smooth Muscle Cells
ISBN: 3319013114 ISBN-13(EAN): 9783319013114
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book features novel findings in the studies of the molecular genesis, networks, microdomains, regulation, and physiological functions of calcium signaling in animal and human airway SMCs.

Автор: Yong-Xiao Wang
Название: Calcium Signaling In Airway Smooth Muscle Cells
ISBN: 3319374583 ISBN-13(EAN): 9783319374581
Издательство: Springer
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Цена: 20896.00 р.
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Описание: This book features novel findings in the studies of the molecular genesis, networks, microdomains, regulation, and physiological functions of calcium signaling in animal and human airway SMCs.

Автор: Rosado Juan A.
Название: Calcium Entry Pathways in Non-Excitable Cells
ISBN: 3319800507 ISBN-13(EAN): 9783319800509
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Calcium entry pathways in non-excitable cells presents a concise synthesis of thoughtfully selected topics covering from the different calcium entry mechanisms in non-excitable cells to the cellular microdomains and organelles regulating the calcium entry process. Particular attention is given to the fascinating group of ion channels involved in different calcium entry pathways as well as the emerging role of these channels in human disease. Calcium entry is an essential mechanism for cellular function in non-excitable cells. In general, two main calcium entry pathways exist in non-excitable cells: one pathway, named store-operated calcium entry (SOCE) requires store depletion and the second pathway is regulated by receptor occupation, but independently on calcium store depletion. The search for the molecular components of calcium entry has identified the stromal interaction molecule 1 (STIM1), as the calcium sensor of the intracellular calcium stores, and Orai as well as TRP channels as the calcium-permeable channels located in the plasma membrane. The location, interactions and function of these channels are finely regulated by a number of scaffolding proteins, membrane microdomains and cellular organelles that fine tune the amount of calcium entering the cell. Cutting-edge and user-friendly, this volume presents relevant background information, critical analysis of the current observations and directions for future research. The book is intended for basic scientists specializing in cellular biology or ion transport, as well as for biomedical researchers.

Название: Calcium Entry Channels in Non-Excitable Cells
ISBN: 1498752721 ISBN-13(EAN): 9781498752725
Издательство: Taylor&Francis
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Цена: 24499.00 р.
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Автор: Kozak, Juliusz Ashot
Название: Calcium Entry Channels in Non-Excitable Cells
ISBN: 0367657902 ISBN-13(EAN): 9780367657901
Издательство: Taylor&Francis
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Цена: 7348.00 р.
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Автор: Stephens Gary
Название: Modulation of Presynaptic Calcium Channels
ISBN: 9400763336 ISBN-13(EAN): 9789400763333
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book presents recent advances in knowledge of the regulation of presynaptic Ca2+ channels. These represent one of the most widely modulated proteins in the body, target of a range of effector pathways and drugs; this range will be fully represented here.

Автор: Gary Fiskum
Название: Cell Calcium Metabolism
ISBN: 1468456008 ISBN-13(EAN): 9781468456004
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Particular attention is given to the molecular basis for plasma membrane transport activities, 2 2 including the ATP-driven Ca + pump, the Na + -Ca + exchange system, and voltage sensitive 2 Ca + channels.

Автор: Senthilkumar Rajagopal; Murugavel Ponnusamy
Название: Calcium Signaling: From Physiology to Diseases
ISBN: 9811353336 ISBN-13(EAN): 9789811353338
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities.

Автор: Stephen W. Schaffer; Ming Li
Название: T-type Calcium Channels in Basic and Clinical Science
ISBN: 3709119545 ISBN-13(EAN): 9783709119549
Издательство: Springer
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Цена: 16977.00 р.
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Описание: The first full treatment of this developing field of research, this collection addresses new therapeutic concepts derived from work on the T-type calcium channel, its molecular, biophysical, and pharmacological properties, and its role in disease pathogenesis.

Автор: Zamponi
Название: Voltage-Gated Calcium Channels
ISBN: 3031088808 ISBN-13(EAN): 9783031088803
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This book covers the tremendous progress in the current understanding of the molecular physiology of voltage-gated calcium channels. This book includes unparalleled insights into structural features of calcium channels due to X-ray crystallography and cryo-EM, which in turn yielded critical information into how these channels function under normal and pathophysiological conditions, and how they interact with calcium channel therapeutics. The chapters investigate how, with the advent of high throughput genome sequencing, numerous mutations in various calcium channel genes have been identified in patients with neurological, cardiovascular, neuropsychiatric and other disorders. This is further complemented through a much larger in vivo toolkit such as knock-out and knock-in mice. The chapters further discuss the increased complexity of calcium channel physiology that arises from mRNA editing and splicing. Finally, the book also provides an overview of the updated research on calcium channel inhibitors that can be used both in vivo and in vitro, and which may serve as a spring board for new calcium channel therapeutics for human disease. Voltage-Gated Calcium Channels is useful for academic researchers at all levels in neuroscience, biophysics, cell biology and drug discovery.

Автор: Lars Kaestner
Название: Calcium signalling
ISBN: 3642346162 ISBN-13(EAN): 9783642346163
Издательство: Springer
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Цена: 15672.00 р.
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Описание: The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells.