Recent Advances In Parkinsons Disease,184, Bjorklund, Anders
Автор: Cristina Sampaio, Christopher G. Goetz... Название: Rating Scales in Parkinson`s Disease Clinical Practice and Research ISBN: 0199783101 ISBN-13(EAN): 9780199783106 Издательство: Oxford Academ Рейтинг: Цена: 12197.00 р. 17424.00-30% Наличие на складе: Есть (1 шт.) Описание: Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one convenient source. Until now. Rating Scales in Parkinson's Disease: Clinical Practice and Research is written for researchers from the medical and social sciences, and for health professionals wishing to evaluate the progress of their patients suffering from Parkinson's Disease. The book is both exhaustive in the description of the scales and informative on the advantages and limitations of each scale. As such, the text clearly guides readers on how to choose and use the instruments available. Extensive cross-referenced tables and charts closely integrate the parts of the book to facilitate readers in moving from one symptom domain to another. Features Based on a consistent and uniform methodology A clear consolidation of material otherwise only available in journals The first comprehensive book of its kind
Автор: Fisher Название: Advances in Alzheimer`s and Parkinson`s Disease ISBN: 038772074X ISBN-13(EAN): 9780387720746 Издательство: Springer Рейтинг: Цена: 43184.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Contains the proceedings of the 2005 ADPD conference. This title deals not only with issues related individually to Alzheimer`s disease and Parkinson`s disease, but also with the integration of these and other related diseases. It covers topics ranging from immunology, neuroscience, and pharmacology to genetics and molecular biology.
Автор: Patrik Brundin; C. Warren Olanow Название: Restorative Therapies in Parkinson`s Disease ISBN: 1489995226 ISBN-13(EAN): 9781489995223 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Never in history has there been greater hope that novel experimental therapies can support significant restoration of brain function. The field of restorative therapies in Parkinson’s disease has passed the initial phase of pioneering experimental and clinical trials. There still does not exist restorative therapy that can be applied in large numbers of patients, but the initial trials have provided us with fundamental insight into the potential for plasticity in the diseased brain. This book gives an overview of the current state-of-the-art research for brain repair, what the challenges are and an indication of what research can provide for the next generation of people with Parkinson’s disease.
Автор: Menza Название: Psychiatric Care In Parkinsons Disease ISBN: 1841844918 ISBN-13(EAN): 9781841844916 Издательство: Taylor&Francis Рейтинг: Цена: 6430.00 р. Наличие на складе: Поставка под заказ.
Описание: A practical guide to the management of various clinical issues seen in patients with Parkinson's Disease (PD), this text emphasizes the need for coordinated care between the various professionals, as well as between professionals and caregivers. Providing an update on current developments in the neurology and management of PD, as well as the understanding and treatment of non-motor aspects of PD, the book also includes a variety of topics such as depression, psychosis, and anxiety
Описание: Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders. The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time. Additionally, neurotoxic animal models are still of high interest to the PD field, as they are being used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.
Описание: This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson’s disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are involved in specific functions as attractive therapeutic targets. It is expected to facilitate critical thought and discussion about the fundamental aspects of neurodegeneration in Parkinson’s disease and foster the development of therapeutic strategies among researchers and graduate students. Theories of idiopathic Parkinson’s etiology support roles for chronic inflammation and exposure to heavy metals or pesticides. Interestingly, as this project proposes, a case can be made that abnormalities in mitochondrial morphology and function are at the core of each of these theories. In fact, the most common approach to the generation of animal and cell-culture models of idiopathic Parkinson’s disease involves exposure to mitochondrial toxins. Even more compelling is the fact that most familial patients harbor genetic mutations that cause disruptions in normal mitochondrial morphology and function. While there remains to be no effective treatment for Parkinson’s disease, efforts to postpone, prevent and “cure” onset mitochondrial aberrations and neurodegeneration associated with Parkinson’s disease in various models are encouraging. While only about ten percent of Parkinson’s patients inherit disease-causing mutations, discovering common mechanisms by which familial forms of Parkinson’s disease manifest will likely shed light on the pathophysiology of the more common idiopathic form and provide insight to the general process of neurodegeneration, thus revealing therapeutic targets that will become more and more accessible as technology improves.
Автор: Verstreken, Patrik Название: Parkinson`s Disease ISBN: 0128037830 ISBN-13(EAN): 9780128037836 Издательство: Elsevier Science Рейтинг: Цена: 11193.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Parkinson’s Disease: Molecular Mechanisms Underlying Pathology explores the molecular pathways at the basis of the cellular defects connected to Parkinson’s disease, the second most common neurodegenerative disease, and the most common movement disorder. This book presents the latest research on the pathways and mechanisms that have been discovered to play a role in Parkinson's pathology. . This focus on mechanisms rather than individual genes allows the contributors to elaborate on overlapping and joint functions of different causative genes.Readers will find descriptions of model systems that present parallels (and differences) between discoveries in different species, demonstrating the importance of multidisciplinary research that spans a broad array of technologies and model organisms. Written from both a cross-methodology and cross-species perspective, the book provides readers with the current state of knowledge on the molecular biology of Parkinson’s.
Автор: Bjorklund, Anders Название: Recent Advances In Parkinsons Disease,183 ISBN: 0444536140 ISBN-13(EAN): 9780444536143 Издательство: Elsevier Science Рейтинг: Цена: 35708.00 р. Наличие на складе: Поставка под заказ.
Описание: Provides an overview on perspectives in genetic research and on the molecular mechanisms of neurodegeneration. This title presents a selection of hot topics in pathophysiological research, from molecular studies to system-level investigations based on in vivo electrophysiological recordings and neurocomputational methods.
Описание: The current book represents an elaborated study of the etiology and pathophysiology of Parkinson's disease, which is a complex neurological disorder. In this book, the ecological and biological agents which become the cause of Parkinson's disease have bee
Автор: Susan H. Fox; Jonathan M. Brotchie Название: Levodopa-Induced Dyskinesia in Parkinson`s Disease ISBN: 1447165020 ISBN-13(EAN): 9781447165026 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book aims to provide a single reference source on levodopa-induced dyskinesias (LID) from `bench to bedside`. Initial chapters review the clinical features and phenomenology of LID with video examples; epidemiology and genetic risk factors for LID are covered as a background to understanding risk factors for developing LID.
Автор: Peter Wellstead; Mathieu Cloutier Название: Systems Biology of Parkinson`s Disease ISBN: 1493901265 ISBN-13(EAN): 9781493901265 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book shows how methods of systems biology have the potential to accelerate research into diseases like Parkinson`s disease (PD). It comprises a set of eight studies of important aspects of PD, covering all relevant scales of space and time.
Автор: Danford Jean Название: Yoga Therapy for Parkinson`s Disease and Multiple Sclerosis ISBN: 1848192991 ISBN-13(EAN): 9781848192997 Издательство: World Scientific Publishing Рейтинг: Цена: 4435.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A key reference for yoga therapists and teachers working with clients affected by Parkinson`s disease or multiple sclerosis, this practical guide outlines both conditions, describes how sessions can be tailored to meet specific and individual needs, and reveals the physical and emotional benefits yoga can unlock for these client groups.
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