Описание: Focuses on Chronic Lymphocytic Leukemia. In this book, topics include: What Have Recent Genomic Advances Taught us About CLL?, Biology of CLL in Different Microenvironments, What is the Significance of Stereotyped BCRs in CLL?, and Evolving Role of Stem Cell Transplantation in CLL.
Автор: Beauchemin Название: Metastasis of Colorectal Cancer ISBN: 9048188326 ISBN-13(EAN): 9789048188321 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers colon cancer metastasis from fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, and more.
Автор: Giovanni Maria Romano Название: Multimodal Treatment of Recurrent Pelvic Colorectal Cancer ISBN: 8847057663 ISBN-13(EAN): 9788847057661 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book analyzes all aspects of modern multimodal treatment of locally recurrent rectal cancer in the pelvis in order to offer a panoramic overview of the different therapeutic options and enable the reader to balance their benefits and drawbacks. Indications for surgery and the surgical techniques themselves, including reconstruction techniques after major exenterative surgery, are clearly described and evaluated. The role of new imaging tools, such as MRI and PET-CT, in staging recurrences and guiding therapy is assessed and detailed consideration is given to the use of neoadjuvant and iterative radiotherapy and the indications for systemic chemotherapy. Morbidity, mortality, oncologic outcomes, and quality of life issues are carefully analyzed and options for pain control and palliation are examined. Finally, a national survey is presented on the state of the art in the surgical treatment of locally recurrent rectal cancer in Italy. While there has been a dramatic fall in the incidence of local pelvic recurrences, their treatment remains a major clinical challenge which requires a multidisciplinary approach and careful selection of the most appropriate strategy in each case. This book will aid practitioners in making the correct decisions in individual patients.
Автор: Rodriguez-Bigas Название: Hereditary Colorectal Cancer ISBN: 1441966021 ISBN-13(EAN): 9781441966025 Издательство: Springer Рейтинг: Цена: 44582.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. This is the first book to cover Hereditary nonpolyposis colorectal cancer, also known as the Lynch syndrome, in one comprehensive text.
Описание: Assembles top experts to write reviews on the management of chronic myelogenous leukemia. This title includes articles: Selection of Therapy: Rational Decisions Based on Molecular Events; Is There a Potential Cure for CML in Current Therapies? Hurdles Toward a Cure for CML: The CML Stem Cell; and, Management of Ph+ ALL and CML Blast Crisis.
Автор: Kim Название: Surgical Treatment of Colorectal Cancer ISBN: 9811338469 ISBN-13(EAN): 9789811338465 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Поставка под заказ.
Описание: This book presents an Asian perspective on how the treatment of colorectal cancer can be optimized and standardized in ways that take into account technological advances and the trend towards individually tailored therapy.
Автор: Correia Название: Colorectal Cancer Liver Metastases ISBN: 3030254852 ISBN-13(EAN): 9783030254858 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Поставка под заказ.
Описание: Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.).
Описание: Focuses on the advances in Colorectal Cancer and includes articles on Management of Multiple Adenomatous Polyps, Imaging of Rectal Cancers, Optimal Management of Small Rectal Cancers, Neoadjuvant Therapy for Locally Advanced Rectal Cancer, Low Anterior Rectal Cancer Resection, Laparoscopy, and Adjuvant Therapy.
Описание: Includes topics such as: Overview of Colorectal Cancer Genetics; Familial Adenomatous Polyposis; MYH Associated Polyposis; Other genetic colorectal cancer syndromes; Hereditary Nonpolyposis Colorectal Cancer - emphasis on MSH2/MLH1; Hereditary Nonpolyposis Colorectal Cancer - emphasis on PMS2/MSH6; and, Familial Colorectal Cancer Syndrome Type X.
Описание: Adenocarcinoma is the predominant malignancy found in the colon and rectum. Colorectal cancer is the third most common cancer diagnosed in the developed world with a high incidence of mortality and morbidity. The average five-year survival rate remains poor at 55%, although the development of new drugs has improved the survival rate of colorectal cancer patients. The prognosis of colorectal cancer remains poor in spite of the development of novel therapeutic strategies. Human colorectal cancer represents a heterogeneous group of diseases, and its molecular classification is increasingly important. Characterization of novel biomarker targets may lead to prolong the survival rate of colorectal cancer. Biomarkers may have a potential role in screening, diagnosis, prognosis and monitoring disease. Mutations in the KRAS gene in ~ 40% of tumors have been reported to be induced by genetic and epigenetic alterations. This book, comprised of four chapters, introduces recent topics regarding colorectal cancer, and provides recent highlighted information concerning prevention, diagnosis and treatment. This book will be of interest to undergraduate and graduate students, biomedical researchers, and medical doctors focused on the fields of molecular and cellular biology, medical sciences, and clinical challenges.
Автор: Anthony J. Mastromarino Название: Biology and Treatment of Colorectal Cancer Metastasis ISBN: 1461294177 ISBN-13(EAN): 9781461294177 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the National Large Bowel Cancer Project 1984 Conference on Biology and Treatment of Colorectal Cancer Metastasis, Houston, Texas, September 13-15, 1984
Автор: Giovanni Maria Romano Название: Multimodal Treatment of Recurrent Pelvic Colorectal Cancer ISBN: 8847039746 ISBN-13(EAN): 9788847039742 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book analyzes all aspects of modern multimodal treatment of locally recurrent rectal cancer in the pelvis in order to offer a panoramic overview of the different therapeutic options and enable the reader to balance their benefits and drawbacks. Indications for surgery and the surgical techniques themselves, including reconstruction techniques after major exenterative surgery, are clearly described and evaluated. The role of new imaging tools, such as MRI and PET-CT, in staging recurrences and guiding therapy is assessed and detailed consideration is given to the use of neoadjuvant and iterative radiotherapy and the indications for systemic chemotherapy. Morbidity, mortality, oncologic outcomes, and quality of life issues are carefully analyzed and options for pain control and palliation are examined. Finally, a national survey is presented on the state of the art in the surgical treatment of locally recurrent rectal cancer in Italy. While there has been a dramatic fall in the incidence of local pelvic recurrences, their treatment remains a major clinical challenge which requires a multidisciplinary approach and careful selection of the most appropriate strategy in each case. This book will aid practitioners in making the correct decisions in individual patients.
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