Contemporary Management Of Esophageal Malignancy, An Issue Of Surgical Clinics,92-5, Denlinger, Chad
Автор: Nagaraju Ganji Purnachandra, Bm Reddy Aramati Название: Exploring Pancreatic Metabolism and Malignancy ISBN: 9813293950 ISBN-13(EAN): 9789813293953 Издательство: Springer Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery.
Описание: Includes articles devoted to the following topics: diagnostic Imaging of pancreatic malignancies, technical conduct of operation for pancreatic malignancies, portal vein resection, neoplasms of the Body and Tail, neoadjuvant therapy for pancreatic malignancies, performance outcomes, and palliative surgery for pancreatic malignancies.
Описание: Covers colposcopy and screening for women at all stages of life, along with the HPV vaccine, treatment options, and what is on the horizon regarding screening methods.
Описание: Includes topics such as: Targeting IGF-1R, Tyrosine Kinase Inhibitors in Lung Cancer, Targeting mTOR, Targeting Hedgehog, Mitotic Inhibitors, Topoisomerase I Inhibitors, and New Strategies and Drugs Inhibiting Folate Pathways.
Автор: Jackson Название: Evolutionary Dynamics of Malignancy ISBN: 3031325729 ISBN-13(EAN): 9783031325724 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Advances in cancer genomics are transforming our understanding of cancer, and have profound implications for its prevention, diagnosis, and treatment. Evolutionary dynamics suggests that as few as two mutations can cause transformation of normal cells into cancer stem cells. A process of Darwinian selection, involving a further three or more mutations, taking place over a period of years, can then result in progression to a life-threatening tumour. In many cases the immune response can recognise and eliminate the mutant cells, but most advanced tumours have mutations that activate immune checkpoints and enable the tumour to hide from the immune system. For the most hard-to-treat tumours, future progress will require molecular diagnostics to detect cancer-causing mutations in healthy subjects, and new drugs or vaccines that prevent the progression process. Chapters of this book deal with the signalling pathways that control cell division, and changes in these pathways in cancer cells. Three cell cycle checkpoints that are often mutated in cancer are analysed in detail. A discussion of chronic myeloid leukaemia illustrates the role of reactive oxygen species in driving progression from a chronic to an acute condition. A single drug that suppresses reactive oxygen can prevent disease progression and turn an otherwise deadly disease into a condition that can be managed to enable many years of normal life. Another chapter discusses chronic myelomonocytic leukaemia, a disease that involves both genetic and epigenetic change. Tumour progression is discussed as a multi-stage process in which cancer stem cells evolve into genetically unstable, invasive, metastatic, drug-resistant growths. Each of these stages can act as targets for drugs or immunomodulators, but the future of cancer treatment lies in understanding tumour dynamics, and arresting malignancy at the earliest possible stage. Evolutionary dynamics is a primarily mathematical technique, but the target readership will be tumour biologists, clinicians, and drug developers. Computational detail is provided in an online supplement, but the main text emphasises the implications of the dynamics for an understanding of tumour biology and does not require mathematical expertise.
Автор: Kataki Название: Fundamentals in Gynaecologic Malignancy ISBN: 9811958599 ISBN-13(EAN): 9789811958595 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a complete representation of all the gynecological cancers covering from the anatomical details of the individual gynecological organs along with the epidemiological pathophysiological aspects of the various gynecological cancers. It also covers the diagnostic workup of various gynecological cancers with recent evidence based treatment protocols. All the major gynecological oncological surgeries are described in a simple way along with photographs for easy understanding in all the chapters. In addition, numerous flowcharts and management algorithms are included in every chapters, as a ready reference for the benefits of the trainees and practitioners. This book includes chapters such as critical care in oncology, oncology nursing, benign and malignant breast disease, hormones and gynecological cancer, cancer infections and vaccines, palliative care which are not often found in many text books. Apart from these, this book has also included chapters like principles and practice of Radiation oncology, surgical oncology and medical oncology, recent advances and imaging in gynecological malignancy to make it a complete package. Thus, it will serve as an excellent reference book for surgical oncologists, general gynecologists, medical and radiation oncologists fellows and trainees.
Автор: Isonishi Seiji, Kikuchi Yoshihiro Название: Molecular Diagnosis and Targeting for Gynecologic Malignancy ISBN: 9813360127 ISBN-13(EAN): 9789813360129 Издательство: Springer Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is intended for periodontal residents and practicing periodontists who wish to incorporate the principles of moderate sedation into daily practice. Comprehensive airway management and rescue skills are then documented in detail so that the patient may be properly managed in the event that the sedation progresses beyond the intended level.
Описание: Despite recent advances, the pathogenesis and therapy of various forms of chronic inflammatory diseases of the gastrointestinal tract remains problematical. and chronic inflammatory bowel diseases, particularly ulcerative colitis, are associated with an increased incidence of carcinoma.
Автор: A.S.D. Spiers Название: Chemotherapy and Urological Malignancy ISBN: 1447113349 ISBN-13(EAN): 9781447113348 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chemotherapy for malignant disease has brought about many rapid and often spectacular improvements in the survival rate of some groups of patients.
Автор: Vincent J. Hearing; Stanley P. L. Leong Название: From Melanocytes to Melanoma ISBN: 1493956744 ISBN-13(EAN): 9781493956746 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.
Автор: Eli Daniel Ehrenpreis; R de W Marsh; William Small Название: Radiation Therapy for Pelvic Malignancy and its Consequences ISBN: 1493953702 ISBN-13(EAN): 9781493953707 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a state-of-the-art review of the role of radiation therapy in various pelvic malignancies as well as the consequences of the radiation in the pelvic tissues.
Автор: C. Bartsch; H. Bartsch; D.E. Blask; D.P. Cardinali Название: The Pineal Gland and Cancer ISBN: 3642640036 ISBN-13(EAN): 9783642640032 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Three years ago, most authors contributing to this book gathered at the Heinrich Fabri Institute of the University of Tubingen at Blaubeuren near Ulm in Germany for the third conference on "Pineal Gland and Cancer." In 1987, the late Derek Gupta organized the second meeting and published the first book on the topic, 10 years after Vera Lapin, as part of the 25th anniversary celebrations of the Vienna Cancer Research Institute, had held the first meeting. It was in Vienna during the 1930s and 1940s that W. Bergmann and P. Engel demonstrated that pineal extracts possess growth inhibitory properties on experimental rodent tumors and R. Hofstatter reported favorable results when these extracts were given to cancer patients. In the 1970s, Vera Lapin and others reported that surgical removal of the pineal gland (pinealectomy) stimulates experimental tumor growth rendering fundamental support for an involvement of the pineal gland in malignancy. A focal question of past and present research in this field is whether the pineal gland exerts its tumor inhibitory activity primarily or exclusively via melatonin. Currently, it appears that the action of melatonin on experimental tumor growth criti- cally depends on the circadian timing of its administration as weH as on the type and stage of cancer, and that primarily highly differentiated tumor ceHs are controHed. Initial clinical applications of the pineal hormone for incurable cancers raise hopes for a promising future use, particularly when combined with other therapies (e. g.
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