Автор: Pierre Busson Название: Nasopharyngeal Carcinoma ISBN: 1493954954 ISBN-13(EAN): 9781493954957 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book takes a "translational medicine and biology" approach to Nasopharyngeal Carcinoma, developing knowledge from basic science towards diagnostic and therapeutic applications and reciprocally proposing new questions for basic scientists.
Автор: Per Hellman Название: Primary Aldosteronism ISBN: 1493946226 ISBN-13(EAN): 9781493946228 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene - KCNJ5 - in about 40% of PA with adenoma.
Описание: The concept of cancer stem cells has great clinical implications. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis.
Автор: Teschendorff Название: Computational and Statistical Epigenomics ISBN: 9402403434 ISBN-13(EAN): 9789402403435 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Нет в наличии.
Описание: This book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigenomics has emerged as a key area of molecular biology, epidemiology and genome medicine. Epigenomics not only offers us a deeper understanding of fundamental cellular biology, but also provides us with the basis for an improved understanding and management of complex diseases. From novel biomarkers for risk prediction, early detection, diagnosis and prognosis of common diseases, to novel therapeutic strategies, epigenomics is set to play a key role in the personalized medicine of the future. In this book we introduce the reader to some of the most important computational and statistical methods for analyzing epigenomic data, with a special focus on DNA methylation. Topics include normalization, correction for cellular heterogeneity, batch effects, clustering, supervised analysis and integrative methods for systems epigenomics. This book will be of interest to students and researchers in bioinformatics, biostatistics, biologists and clinicians alike. Dr. Andrew E. Teschendorff is Head of the Computational Systems Genomics Lab at the CAS-MPG Partner Institute for Computational Biology, Shanghai, China, as well as an Honorary Research Fellow at the UCL Cancer Institute, University College London, UK.
Описание: Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.
Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and the bench with information needed to accelerate clinically-effective CNS drug discovery.
Автор: Villaverde, A Название: Nanoparticles In Translational Science And Medicine,104 ISBN: 0124160204 ISBN-13(EAN): 9780124160200 Издательство: Elsevier Science Рейтинг: Цена: 21054.00 р. Наличие на складе: Нет в наличии.
Описание: Explores advances in basic research on nanoparticles in translational science and medicine and how this knowledge is leading to advances in the various fields. This title provides a forum for discussion of new discoveries, approaches, and ideas. It is suitable for researchers involved in molecular biology and related fields.
Автор: Xiangdong Wang Название: Bioinformatics of Human Proteomics ISBN: 9400758103 ISBN-13(EAN): 9789400758100 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Full of useful practical designs and methodologies, this book discusses developing techniques and applications in the field of protein bioinformatics, featuring contributions from expert researchers on topics including protein analysis and drug development.
Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and bench with information needed to accelerate clinically-effective CNS drug discovery.
Описание: This book offers a comprehensive study of biological molecules acquired from marine organisms, which have been exploited for drug discovery with the aim to treat human diseases.
Автор: Alexander von Gabain; Christoph Klade Название: Development of Novel Vaccines ISBN: 3709117046 ISBN-13(EAN): 9783709117040 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covering the entire process of developing a vaccine-from early, basic research right up to the final product itself, and approaching the subject from a variety of perspectives, this volume will be required reading for researchers engaged in vaccine creation.
Автор: Grune, Tilman Название: The Proteasomal System In Aging And Disease,109 ISBN: 0123978637 ISBN-13(EAN): 9780123978639 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Нет в наличии.
Описание: Discusses research of proteasomes and proteasome-associated proteins and cellular systems. This title also discusses the knowledge of the structure, function, and regulation of the proteasomal system. It describes the role of the proteasome in aging and disease.
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