Understanding Lipid Metabolism with Microarrays and Other Omic Approaches, Berger, Alvin

Автор: Yann Chevolot
Название: Carbohydrate Microarrays
ISBN: 1493958666 ISBN-13(EAN): 9781493958665
Издательство: Springer
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Цена: 16070.00 р.
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Описание: Carbohydrate microarrays emerged as a key technology for the deciphering of the glycospace by providing a multiplex technology where tens to hundreds of carbohydrates/protein interactions can be probed in parallel. Carbohydrate Microarrays: Methods and Protocols aims to give the reader the theoretical and experimental clues necessary for the fabrication and implementation of carbohydrate microarrays. This requires three essential steps: 1) to obtain the carbohydrate probes (monosacharides, oligosacchrides, polysacchairdes, glycoconjugates or glycoclusters), 2) to immobilize these probes, and 3) to implement the protocols for biological/biochemical interaction with the desired target. This volume gives an overview of carbohydrate microarray and carbohydrate chemistry and illustrates different detection techniques and their applications. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Carbohydrate Microarrays: Methods and Protocols compiles a catalogue of protocols on carbohydrate microarrays to span the needs of researchers around the globe.

Название: DNA Microarrays and Related Genomics Techniques
ISBN: 0367391732 ISBN-13(EAN): 9780367391737
Издательство: Taylor&Francis
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Цена: 9798.00 р.
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Описание:

Considered highly exotic tools as recently as the late 1990s, microarrays are now ubiquitous in biological research. Traditional statistical approaches to design and analysis were not developed to handle the high-dimensional, small sample problems posed by microarrays. In just a few short years the number of statistical papers providing approaches to analyzing microarray data has gone from almost none to hundreds if not thousands. This overwhelming deluge is quite daunting to either the applied investigator looking for methodologies or the methodologist trying to keep up with the field. DNA Microarrays and Related Genomics Techniques: Design, Analysis, and Interpretation of Experiments consolidates discussions of methodological advances into a single volume.

The book's structure parallels the steps an investigator or an analyst takes when conducting and analyzing a microarray experiment from conception to interpretation. It begins with foundational issues such as ensuring the quality and integrity of the data and assessing the validity of the statistical models employed, then moves on to cover critical aspects of designing a microarray experiment. The book includes discussions of power and sample size, where only very recently have developments allowed such calculations in a high dimensional context, followed by several chapters covering the analysis of microarray data. The amount of space devoted to this topic reflects both the variety of topics and the effort investigators have devoted to developing new methodologies. In closing, the book explores the intellectual frontier - interpretation of microarray data. It discusses new methods for facilitating and affecting formalization of the interpretation process and the movement to make large high dimensional datasets public for further analysis, and methods for doing so.

There is no question that this field will continue to advance rapidly and some of the specific methodologies discussed in this book wil

Автор: Nuber, Ulrike
Название: DNA Microarrays
ISBN: 0415358663 ISBN-13(EAN): 9780415358668
Издательство: Taylor&Francis
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Цена: 10717.00 р.
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Автор: Cretich
Название: Peptide Microarrays
ISBN: 1071627317 ISBN-13(EAN): 9781071627310
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This detailed volume provides an updated overview of current uses of peptide microarray technology, showcasing consolidated applications while highlighting some of the most intriguing novelties and emerging fields of use. The methodologies within this collection are of considerable value for both advanced users and new-comers in the peptide microarray arena, as the renowned contributors describe full coverage of the aspects related to their workflows, from microchip manufacturing to advanced analytical applications. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Peptide Microarrays: Methods and Protocols, Third Edition aims to make the use of peptide microarrays more and more accessible while stimulating further developments to sustain exciting discoveries in the biochemistry and medicine realms.

Автор: Allison
Название: DNA Microarrays and Related Genomics Techniques
ISBN: 0824754611 ISBN-13(EAN): 9780824754617
Издательство: Taylor&Francis
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Цена: 20671.00 р.
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Описание: Explores critical aspects of designing a microarray experiment, including power and sample size. This book assesses the validity of statistical methods and describes how to ensure the quality and integrity of data. It discusses methods for interpreting microarray data and examines the various issues associated with analysis.

Автор: Cretich
Название: Peptide Microarrays
ISBN: 1071627341 ISBN-13(EAN): 9781071627341
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This detailed volume provides an updated overview of current uses of peptide microarray technology, showcasing consolidated applications while highlighting some of the most intriguing novelties and emerging fields of use. The methodologies within this collection are of considerable value for both advanced users and new-comers in the peptide microarray arena, as the renowned contributors describe full coverage of the aspects related to their workflows, from microchip manufacturing to advanced analytical applications. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Peptide Microarrays: Methods and Protocols, Third Edition aims to make the use of peptide microarrays more and more accessible while stimulating further developments to sustain exciting discoveries in the biochemistry and medicine realms.

Автор: Jang B. Rampal
Название: Microarrays
ISBN: 1617378526 ISBN-13(EAN): 9781617378522
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This second part in the two-volume work Microarrays details applications and data analysis. It includes insight into non-mammalian vertebrate systems, processes and protocols for high quality glass-based microarrays.

Автор: Jang B. Rampal
Название: Microarrays
ISBN: 1617376639 ISBN-13(EAN): 9781617376634
Издательство: Springer
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Цена: 23058.00 р.
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Описание: These two volumes present information in designing and fabricating arrays and binding studies with biological analytes. This is done while providing the reader with a broad description of microarray technology tools and their potential applications.

Автор: Ulrike Korf
Название: Protein Microarrays
ISBN: 1493957767 ISBN-13(EAN): 9781493957767
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Protein microarrays can overcome the sensitivity and sample limitations of functional proteomics. This volume is an exhaustive and up-to-date presentation of robust protein microarray strategies that furthers the advance of this powerful laboratory technology.

Автор: Predki, Paul F.
Название: Functional Protein Microarrays in Drug Discovery
ISBN: 0849398096 ISBN-13(EAN): 9780849398094
Издательство: Taylor&Francis
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Цена: 33686.00 р.
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Автор: Marina Cretich; Marcella Chiari
Название: Peptide Microarrays
ISBN: 1493949683 ISBN-13(EAN): 9781493949687
Издательство: Springer
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Цена: 13275.00 р.
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Описание:

Part I: Peptide Arrays: Cutting-Edge Methods and Technology

1. Peptide Arrays on Planar Supports

Vнctor Tapia and Rudolf Volkmer

2. High-Throughput Microarray Incubations Using Multi-Well Chambers

Johannes Zerweck, Ulf Reimer, Janina Jansong, Nikolaus Pawlowski, Christoph Tersch, Maren Eckey, and Tobias Knaute

3. Analysis of Protein Tyrosine Kinase Specificity Using Positional Scanning Peptide Microarrays

Yang Deng and Benjamin E. Turk

4. Secondary Structure Determination of Peptides and Proteins After Immobilization

Stella H. North and Chris R. Taitt

5. Peptides and Anti-Peptide Antibodies for Small and Medium Scale Peptide and Anti-Peptide Affinity Microarrays: Antigenic Peptide Selection, Immobilization, and Processing

Fan Zhang, Andrea Briones, and Mikhail Soloviev

6. Low-Cost Peptide Microarrays for Mapping Continuous Antibody Epitopes

Ryan McBride, Steven R. Head, Phillip Ordoukhanian, and Mansun Law

7. The Peptide Microarray-Based Resonance Light Scattering Assay for Sensitively Detecting Intracellular Kinase Activity

Tao Li, Xia Liu, Dianjun Liu, and Zhenxin Wang

8. Anomalous Reflection of Gold: A Novel Platform for Biochips

Amir Syahir, Kin-ya Tomizaki, Kotaro Kajikawa, and Hisakazu Mihara

9. High Throughput Peptide Screening on a Bimodal Imprinting Chip Through

Автор: Preeti Arivaradarajan; Gauri Misra
Название: Omics Approaches, Technologies And Applications
ISBN: 9811329249 ISBN-13(EAN): 9789811329241
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This book is a concerted effort to put together the rapidly growing facets of biological data. It provides a platform for the readers to think about integrative approaches to solve complex biological problems. This fundamental book deals with the simplest concepts of omics to recent advancements in the field. The content is divided into seven chapters that provide insight into various omics approaches, omics technologies, and its applications. Each chapter delves into different molecular scales: genomics, transcriptomics, proteomics, and metabolomics. Further to provide a holistic view a chapter detailing microbiome has been included in the book. The sub-sections in the chapters is dedicated to introducing the various analytical tools such as next generation sequencing, chromatin immunoprecipitation, mass spectrometry, peptide mass fingerprinting, RNA Seq and NMR spectroscopy. It entails a chapter focused on the bioinformatics resources for analysis of the omics data. In summary, this comprehensive book emphasizes the recent advancements in the study of biomolecules spanning from DNA to metabolites.