Описание: This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD.
Описание: This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As such, this book evaluates various strategies for sample preparation for proteomic and ionomic studies in order to simplify complex serum samples and allow the quantification of chemical species (proteins and metal ions), which are potential candidates for BD biomarkers. In addition, it describes the development of a new membrane-based methodology for extracting urine proteins to be used in biomarker discovery.
This book presents two main sets of paper-based analytical systems. The first set is a platform for the analysis of glucose, cholesterol and uric acid in biological samples, and the second set is a cutting-edge electronic tongue system for the analysis of beverages (mineral water, beer, wine). This thesis also provides an extensive review of 33 methods of enzyme immobilization on paper which have been evaluated to enhance the storage stability of the proposed system for biomarker detection. From a practical perspective, this thesis covers a diverse set of topics related to paper-based sensing, including colorimetric and electrochemical detection methods, different sets of architecture (spot-tests, lateral and tangential flow assays), methods of fabrication (wax printing, cutting, impregnation with polymers), measurements in stationary and flow conditions as well computer modeling of proposed systems and sophisticated data analysis using chemometric techniques. This book is useful for PhD students working in this or a related field who require detailed information about methodology and background to this research.
Описание: This book provides a critical overview of analytical methods used for the determination of pesticide residues and other contaminants in food and environmental samples by modern instrumental analysis. The levels of these chemicals found in food, regulatory aspects and the monitoring of pesticides in the environment are also described.
Описание: Introduction.- Literature Review.- Analysis of glucose, Cholesterol and uric acid.- Electronic tongue system for the analysis of beverages.- Conclusions.
Описание: Chapter 1 outlines the background and examples of 18Op studies in sediments, soils, fresh water, mineral fertilizers, and plants. Chapter 5 discusses planning and designing of a study using 18Op, external quality assurance with an example of an inter-laboratory study.
Описание: Chapter 1 outlines the background and examples of 18Op studies in sediments, soils, fresh water, mineral fertilizers, and plants. Chapter 5 discusses planning and designing of a study using 18Op, external quality assurance with an example of an inter-laboratory study.
Описание: 1. Introduction.- 2. Theory of Combined Acoustic-Gravitational Field.- 3. Principle of Detection Using Particle Levitation in a Coupled Acoustic-Gravitational Field.- 4. Detection of the Avidin-Biotin Reaction.- 5. Label-Free Detection for the DNA/RNA molecules.- 6. Aptamer-Based Sensing of Small Organic Molecules.
Автор: Hussain, Chaudhery Mustan Название: Handbook Of Analytical Techniques For Forensic Samples ISBN: 0128223006 ISBN-13(EAN): 9780128223000 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Handbook of Analytical Techniques for Forensic Samples: Current and Emerging Developments discusses in detail the current trends and latest analytical techniques and methods commonly employed in forensic analysis in order to ensure the proper facilitation of justice. This book is useful for readers who wish to stay updated on the latest trends in the forensic analysis of samples encountered at crime scenes. Technological advancements, such as biosensors, nanotechnology, and taggant technology have upped the level of analysis in forensic science. These emergent technologies, incorporated with existing analytical techniques, are leading to more precise, accurate, and specific examination of forensic samples. Lab-on-a-chip technology has also eased several kinds of on-site analyses done by investigating teams at different types of crime scenes. This book covers the evolution of forensic sample analysis as well as these emerging trends and new technologies.
Описание: This book shows the availability and potential of the coupled acoustic-gravitational (CAG) field for trace-level biosensing. The proposed detection scheme also allows the evaluation of the kinetics and thermodynamics of the reaction occurring on a single microparticle (MP). This method has wide applicability in important fields, involving not only chemistry but also life, environmental, and medical sciences. The author proposes novel trace-level biosensing based on measurements of the levitation coordinate shift of an MP in the CAG field. The levitation coordinate of the MP in the CAG field is determined by its density and compressibility. The levitation coordinate shift is induced by the binding of gold nanoparticles (AuNPs) to the MP through interparticle reactions. Therefore, the quantity of molecules involved in the reaction can be determined from the levitation coordinate shift. The author demonstrates the zmol level detection for biotin, DNA/RNA, and organic molecules. In addition, the kinetics and thermodynamics are evaluated for various reactions occurring between the MP and AuNP, such as the avidin-biotin reaction, direct hybridization, sandwich hybridization, and aptamer-target complexation. This book provides a new concept based on the CAG field, in which the extent of a reaction is converted into the levitation coordinate shift, that is, “length.” The proposed method has many advantages over other methods, e.g., high biocompatibility, high applicability, and short analysis time. In addition, because the apparatus used in this study is inexpensive and easy to miniaturize, this method is useful in important practical fields, such as forensic and environmental science and diagnosis. Thus, this book inspires many researchers to apply the present method to their own fields of interest.
Описание: This book illustrates the significance of various optical spectroscopy and microscopy techniques, including absorption spectroscopy, fluorescence spectroscopy, infrared spectroscopy, and Raman spectroscopy for deciphering the nature of biological molecules. The content of this book chiefly focuses on (1) the principle, theory, and instrumentation used in different optical spectroscopy techniques, and (2) the application of these techniques in exploring the nature of different biomolecules (e.g., proteins, nucleic acids, enzymes, and carbohydrates). It emphasizes the structural, conformational and dynamic, and kinetic including the changes in biomolecules under a range of conditions. In closing, the book summarizes recent advances in the field of optical spectroscopic and microscopic techniques.
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