Автор: Sadegh Babashah Название: MicroRNAs: Key Regulators of Oncogenesis ISBN: 3319037242 ISBN-13(EAN): 9783319037240 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state.
Автор: Schmitz Название: Systems Biology of MicroRNAs in Cancer ISBN: 3031083555 ISBN-13(EAN): 9783031083556 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an update on the latest development in the field of microRNAs in cancer research with an emphasis on translational research. Since the early 2000s, microRNAs have been recognized as important and ubiquitous regulators of gene expression. Soon it became evident that their deregulation can cause human diseases including cancer. This book focuses on the emerging opportunities for the application of microRNA research in clinical practice. In this context, computer models are presented that can help to identify novel biomarkers, e.g. in circulating microRNAs, and tools that can help to design microRNA-based therapeutic interventions. Other chapters evaluate the role of microRNAs in immunotherapy, immune responses and drug resistance. Covering key topics on microRNAs in cancer research this book is a valuable resource for both emerging and established microRNA researchers who want to explore the potential of microRNAs as therapeutic targets or co-adjuvants in cancer therapies.
Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics.
This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.
Автор: William C.S. Cho Название: MicroRNAs in Cancer Translational Research ISBN: 9400789971 ISBN-13(EAN): 9789400789975 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This timely publication includes chapters by world-renowned experts and focuses on our current understanding of miRNAs. It assesses their potential applications in cancer diagnosis, prognosis and therapeutic targets, and identifies areas for further research.
Описание: Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression.
Автор: Sand Название: MicroRNAs in malignant tumors of the skin ISBN: 3658127937 ISBN-13(EAN): 9783658127930 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Michael Sand gives the reader an overview ofcurrent techniques in expression profiling of miRNAs and their maturationmachinery in the skin. This book is a postdoctoral thesis on miRNAs incutaneous malignant melanoma and non-melanoma skin cancer with a focus on themiRNA processing machinery and miRNA expression profiling. The researchpresented in this book was performed in the Dermatologic Surgery Section at theDepartment of Dermatology, Venereology and Allergology of the Ruhr-UniversityBochum, Germany and gives the reader an overview of current techniques inexpression profiling of miRNAs and their maturation machinery in the skin.
Автор: Prasad Название: Role of MicroRNAs in Cancers ISBN: 9811691851 ISBN-13(EAN): 9789811691850 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses the potential roles of miRNA as a crucial regulator in cancer biology. It examines the regulation of drug resistance by miRNAs in cancers and the mechanism of their deregulated expression. The book discusses the role and molecular mechanism of miRNA in regulating cellular proliferation and cell cycle. It analyses circulating miRNAs as biomarkers for cancer diagnosis and prognosis. It also analyzes the role of miRNA as a modulator of the development and function of tumor-associated immune cells. It explores the cross-talk between miRNA and reactive oxygen species (ROS) in pathogenesis, cancer therapeutic tolerance, and resistance. It provides insights into the role of miRNA in cancer angiogenesis, metastasis and describes strategies and associated challenges of miRNA-based therapies.
Автор: Sadegh Babashah Название: MicroRNAs: Key Regulators of Oncogenesis ISBN: 3319376136 ISBN-13(EAN): 9783319376134 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state.
Автор: Michael Sand Название: MicroRNAs in malignant tumors of the skin ISBN: 3658215119 ISBN-13(EAN): 9783658215118 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Michael Sand gives the reader an overview ofcurrent techniques in expression profiling of miRNAs and their maturationmachinery in the skin. This book is a postdoctoral thesis on miRNAs incutaneous malignant melanoma and non-melanoma skin cancer with a focus on themiRNA processing machinery and miRNA expression profiling.
Автор: Singh Shree Ram Название: MicroRNA in Development and in the Progression of Cancer ISBN: 1489980644 ISBN-13(EAN): 9781489980649 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF-? and EGFR. Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease. Recently, many studies have found miRNAs have crucial regulatory roles in Cancer stem cells (CSCs) a kind of tumor initiating cells (TICs) and dormancy. Findings also suggest that DNA methylation may be important in regulating the expression of many miRNAs in several cancer initiating cells. Several miRNAs are known to either upregulated or downregulated in CSCs when compared to non-cancerous cells from the same tissues. CSCs are a small subpopulation of cells identified in a variety of tumors and involve in self-renewal, differentiation, chemoresistance and tumorigenesis. The volume will give a comprehensive account of important advancements in the area of miRNAs and cancer.
Автор: Wei Wu Название: MicroRNA and Cancer ISBN: 1493984853 ISBN-13(EAN): 9781493984855 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume details basic principles of experimental and computational methods for the study of microRNAs in cancer research and, therefore, provides a firm grounding for those who wish to develop further applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, MicroRNA and Cancer: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field
Автор: Mettinger Название: Exosomes, Stem Cells and MicroRNA ISBN: 3319744690 ISBN-13(EAN): 9783319744698 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
