Advances In Animal Alternatives For Safety And Efficacy Testing, Salem, Harry

Автор: Eskes
Название: Validation of Alternative Methods for Toxicity Testing
ISBN: 3319338242 ISBN-13(EAN): 9783319338248
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.

Автор: Peteu Serban, Szunerits Sabine, Bayachou Mekki
Название: Peroxynitrite Detection in Biological Media: Challenges and Advances
ISBN: 1782620850 ISBN-13(EAN): 9781782620853
Издательство: Royal Society of Chemistry
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Цена: 33581.00 р.
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Описание: Peroxynitrite detection and quantification provides critical information in understanding its biological implications. It will be welcomed by the community particularly medicinal and analytical chemists, developers of sensors and probes and analytical equipment manufacturers.

Автор: Balls, Michael; Combes, Robert D.; Bhogal, Nirmala (Eds.)
Название: New Technologies for Toxicity Testing
ISBN: 1461430542 ISBN-13(EAN): 9781461430544
Издательство: Springer
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Цена: 22359.00 р.
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Описание: The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment. Of course, many of the techniques and methods described in this volume are in the early stages of development, and much work will be needed to ensure their further improvement, optimisation and validation. However, we are confident that this will be achieved and that, just as with the in vitro assays that were validated and granted regulatory acceptance over the last decade, these, and many other new, advanced methods, will likewise become part of the toxicologist’s improved toolbox for coping with increasingly stringent and numerous regulatory requirements and test chemicals, while placing less reliance on traditional testing paradigms.

Автор: Margo DeMello
Название: Speaking for Animals: Animal Autobiographical Writing
ISBN: 0415808995 ISBN-13(EAN): 9780415808996
Издательство: Taylor&Francis
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Цена: 24499.00 р.
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Описание: For thousands of years, in the myths and folktales of people around the world, animals have spoken in human tongues. Western and non-Western literary and folkloric traditions are filled with both speaking animals, some of whom even narrate or write their own autobiographies.

Название: Colonialism and Animality
ISBN: 0367856123 ISBN-13(EAN): 9780367856120
Издательство: Taylor&Francis
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Цена: 22202.00 р.
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Описание: Colonialism and Animality: Anti-Colonial Perspectives in Critical Animal Studies explores some of the ways that the oppression of Indigenous persons and more-than-human animals are interconnected.

Автор: Hajime Kojima; Troy Seidle; Horst Spielmann
Название: Alternatives to Animal Testing
ISBN: 9811324468 ISBN-13(EAN): 9789811324468
Издательство: Springer
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Цена: 6986.00 р.
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Описание: This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.

Название: Nutraceuticals
ISBN: 0128210389 ISBN-13(EAN): 9780128210383
Издательство: Elsevier Science
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Цена: 26107.00 р.
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Описание: Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs.

Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines.

Автор: Baker Judith
Название: Advances in Toxicity and Drug Testing
ISBN: 1632420376 ISBN-13(EAN): 9781632420374
Издательство: Неизвестно
Цена: 22806.00 р.
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Автор: Moumtzoglou, Kastania & Archonda
Название: Laboratory Management Information Systems
ISBN: 1466663200 ISBN-13(EAN): 9781466663206
Издательство: Mare Nostrum (Eurospan)
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Цена: 35759.00 р.
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Описание: Technological advances have revolutionized the way we manage information in our daily workflow. The medical field has especially benefitted from these advancements, improving patient treatment, health data storage, and the management of laboratory samples and results.Laboratory Management Information Systems: Current Requirements and Future Perspectives responds to the issue of administering appropriate regulations in a medical laboratory environment in the era of telemedicine, electronic health records, and other e-health services.Exploring concepts such as the implementation of ISO 15189:2012 policies and the effects of e-health application, this book is an integral reference source for researchers, academicians, students of health care programmes, health professionals, and laboratory personnel.

Автор: W.F. List; M.M. M?ller; M.J. McQueen
Название: Advances in Critical Care Testing
ISBN: 3540625909 ISBN-13(EAN): 9783540625902
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This volume contains clinical and laboratory studies related to critically ill patients whose care involves technology, therapy, and application or interpretation of tests. Topics include inflammation, infection, stress, hypoxia, ischaemia, cardiology, haemodynamics, and blood gases.

Автор: DeMello Margo
Название: Speaking for Animals: Animal Autobiographical Writing
ISBN: 1138920649 ISBN-13(EAN): 9781138920644
Издательство: Taylor&Francis
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Цена: 6736.00 р.
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Описание:

For thousands of years, in the myths and folktales of people around the world, animals have spoken in human tongues. Western and non-Western literary and folkloric traditions are filled with both speaking animals, some of whom even narrate or write their own autobiographies. Animals speak, famously, in children's stories and in cartoons and films, and today, social networking sites and blogs are both sites in which animals--primarily pets--write about their daily lives and interests. Speaking for Animals is a compilation of chapters written from a variety of disciplines that attempts to get a handle on this cross cultural and longstanding tradition of animal speaking and writing. It looks at speaking animals in literature, religious texts, poetry, social networking sites, comic books, and in animal welfare materials and even library catalogs, and addresses not just the "whys" of speaking animals, but the implications, for the animals and for ourselves.

Название: The Rise of Critical Animal Studies
ISBN: 1138125911 ISBN-13(EAN): 9781138125919
Издательство: Taylor&Francis
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Цена: 7042.00 р.
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Описание: As the scholarly and interdisciplinary study of human/animal relations become crucial to the urgent questions of our time, notably in relation to environmental crisis, this volume explores the inner tensions within the broad field of animal studies and provides a platform for the latest critical thinking on the condition and experience of animals.