Автор: D. Celentano, M. Szklo Название: Gordis Epidemiology - 6th ed. ISBN: 0323552293 ISBN-13(EAN): 9780323552295 Издательство: Elsevier Science Рейтинг: Цена: 7073.00 р. Наличие на складе: Поставка под заказ.
Описание:
From the Department of Epidemiology at Johns Hopkins University and continuing in the tradition of award-winning educator and epidemiologist Dr. Leon Gordis, comes the fully revised 6th Edition of Gordis Epidemiology. This bestselling text provides a solid introduction to basic epidemiologic principles as well as practical applications in public health and clinical practice, highlighted by real-world examples throughout. New coverage includes expanded information on genetic epidemiology, epidemiology and public policy, and ethical and professional issues in epidemiology, providing a strong basis for understanding the role and importance of epidemiology in today's data-driven society.
Covers the basic principles and concepts of epidemiology in a clear, uniquely memorable way, using a wealth of full-color figures, graphs, charts, and cartoons to help you understand and retain key information.
Reflects how epidemiology is practiced today, with a new chapter organization progressing from observation and developing hypotheses to data collection and analyses.
Features new end-of-chapter questions for quick self-assessment, and a glossary of genetic terminology.
Provides more than 200 additional multiple-choice epidemiology self-assessment questions online.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Название: Epigenetic cancer therapy ISBN: 0323913679 ISBN-13(EAN): 9780323913676 Издательство: Elsevier Science Рейтинг: Цена: 23917.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Alexander Meissner; J?rn Walter Название: Epigenetic Mechanisms in Cellular Reprogramming ISBN: 3662510626 ISBN-13(EAN): 9783662510629 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offering an overview of current topics and concepts concerning mechanisms and consequences of epigenetic reprogramming, this book addresses biomedical researchers in search of more detailed knowledge of novel mechanisms and methods of study.
Автор: Saldanha, Sabita Название: Epigenetic Mechanisms in Cancer ISBN: 0128095520 ISBN-13(EAN): 9780128095522 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Поставка под заказ.
Описание: Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offer a unique evaluation of signature differences in of childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes.
Offers broad coverage that is applicable to audiences in various area of cancer research - population studies, diagnostics, prognosis, prediction, therapy, risk, etc.
Provides critical review analysis of the topics that will clarify and delineate the potential roles of epigenetic signatures in cancer management
Covers basic, as well as, clinical areas of epigenetic mechanisms in tumorigenesis
Features contributions by leading experts in the field
Provides comprehensive coverage of current epigenetic signatures involved in the etiology of various cancers and miRNAs
Автор: Michels Karin B. Название: Epigenetic Epidemiology ISBN: 3030944743 ISBN-13(EAN): 9783030944742 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Now in its second edition, this book provides a state of the art overview on basic concepts of epigenetic epidemiology and a comprehensive review of the rapidly evolving field of human epigenetics. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. Unlike our genetic inheritance, our epigenome is malleable throughout the lifecourse and is shaped by our environmental experiences. Population-based epidemiologic studies increasingly incorporate epigenetic components. These so called epigenome-wide association studies (EWAS) contribute substantially to our understanding of the relevance of epigenetic marks, such as DNA methylation, histone modification, and non-coding RNAs for disease causation. Written by leading experts in the field, the book opens with a comprehensive introduction of the principles of epigenetic epidemiology and discusses challenges in study design, analysis, and interpretation. It summarizes the latest advances in epigenetic laboratory techniques, the influence of age and environmental factors on shaping the epigenome, the epigenetic clock, and the role of epigenetics in the developmental origins hypothesis. The final part focuses on epigenetic epidemiology of various health conditions such as imprinting disorders, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, metabolic disorder and vascular disease, as well as neurodevelopmental and psychiatric disorders. Given its scope, Epigenetic Epidemiology is an indispensable resource for researchers working in the field of human epigenetics.
Автор: Vladimir A. Botchkarev; Sarah E. Millar Название: Epigenetic Regulation of Skin Development and Regeneration ISBN: 3030132374 ISBN-13(EAN): 9783030132378 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Поставка под заказ.
Описание: This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
Автор: Cabej, Nelson R. (department Of Biology, Universit Название: Epigenetic mechanisms of the cambrian explosion ISBN: 0128143118 ISBN-13(EAN): 9780128143117 Издательство: Elsevier Science Рейтинг: Цена: 11957.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Epigenetic Mechanisms of the Cambrian Explosion provides readers with a basic biological knowledge and epigenetic explanation of the biological puzzle of the Cambrian explosion, the unprecedented rapid diversification of animals that began 542 million years ago. During an evolutionarily instant of 10 million years, which represents only 0.3% of the time of existence of life on Earth, or less than 2% of the time of existence of metazoans, all of the 30 extant body plans, major animal groups (phyla) and several extinct groups appeared. The work helps address this phenomena and tries to answer remaining questions for evolutionary biology, epigenetics, and scientific researchers.
The book recognizes and presents objective representations of alternative theories for epigenetic evolution in this period, with the author drawing on his epigenetic theory of evolution to explain the causal basis of the Cambrian explosion. Both empirical evidence and theoretical arguments are presented in support of this thought-provoking epigenetic theory.
Explains the Cambrian explosion from an entirely epigenetic view
Takes a causal rather than descriptive approach to the phenomenon
Allows for a broad readership, including those with only a basic biological knowledge, while maintaining scientific rigor
Описание: This book presents a major research program on epigenetic mechanisms of cell programming and reprogramming. The program was launched by the National Natural Science Foundation of China during the 11th Five-Year Plan period, which was started in October 2008 and concluded at the end of 2016. It first summarizes the epigenetic research plans and the current situation of epigenetic research in China and the international frontier. With the application of interdisciplinary research methods, the book discusses the development trends of epigenetic research, such as mechanisms of establishment and maintenance of epigenetic information and epigenetic regulation on reproduction and development. It also presents a variety of research achievements. For example, the discovery of new epigenetic regulators and chromatin remodulaters and their biological functions and mechanisms are highlighted. Several regulation mechanisms of cell differentiation and trans-differentiation are discussed, especially the discovery of the key factors to promote the trans-differentiation of somatic cells to hepatocytes. In addition, this book puts forward some key academic fields with increasing importance, such as biochemistry, cell biology, and clinical medicine. Given its scope, the book is of interest to researchers who work in cell biology, biochemistry, structural biology, bioinformatics, clinical medicine, and other related fields.
Автор: Torday John, Miller Jr William Название: Cellular-Molecular Mechanisms in Epigenetic Evolutionary Biology ISBN: 3030381323 ISBN-13(EAN): 9783030381325 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Chapter 1. Introduction
Chapter 2. Darwin, the Modern Synthesis, and a New Biology
Chapter 3. Cognition and the living condition
Chapter 4. What is consciousness? An Evolutionary Perspective
Chapter 5. Networking from the Cell to Quantum Mechanics as Consciousness
Chapter 6. The Nature of information and its communication
Chapter 7. The information cycle and biological information management
Chapter 8. Communication and the accumulation of genetic information
Chapter 9. Non-genic means of information reception and exchange
Chapter 10. The primacy of the unicellular state
Chapter 11. Phenotype, niche construction and natural cellular engineering
Chapter 12. Holobionts
Chapter 13. Four Domains: Cognition-based evolution
Chapter 14. Reconciling physics and biology
Chapter 15. What does this mean for evolution?
Chapter 16. Conclusion: Cellular-molecular evolution in the 21st century
Автор: Elser, Amin Название: Gene editing, epigenetic, cloning and therapy ISBN: 1524621994 ISBN-13(EAN): 9781524621995 Издательство: Неизвестно Рейтинг: Цена: 3516.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Explores the many types and trends of ads issued by both domestic car manufacturers and importers in three main sections: "Family Marques", "Luxury and Sporting Marques" and "Imported Marques". Twelve appendices provide information on various topics ranging from the value of the pound in 1958-70 and imports of cars from selected countries, to car manufacturers` and importers` advertising agencies.
Описание: Human trafficking is one of the most pressing social justice issues of our time. Though renewed interest in this issue among Christians is a wonderful thing, misinformed and misguided efforts can do more harm than good. Written by seasoned leaders and grounded in theology and up-to-date data, this accessible and compelling handbook will educate churches and organizations for truly effective work.
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