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Emergence of In Vitro 3D Systems to Model Human Malaria, Kulkeaw


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Цена: 18167.00р.
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Автор: Kulkeaw
Название:  Emergence of In Vitro 3D Systems to Model Human Malaria
ISBN: 9789819906901
Издательство: Springer
Классификация:
ISBN-10: 9819906903
Обложка/Формат: Hardback
Вес: 0.00 кг.
Дата издания: 13.06.2023
Язык: English
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book illustrates the importance and advances of the disease model for malaria, a globally affected public health problem. This book provides comprehensive information on the malaria biology in a liver and all in vitro platforms for liver-stage malaria, including principles, protocols, applications for disease modeling and drug screening, and their limitations. The initial chapter describes the basis of stem cells in liver generation during development and in adults. The subsequent chapters highlight recent and emerging advances in liver organoid and liver-on-a-chip in modeling malaria. The book presents current protocols and methods to generate liver organoid and liver-on-a-chip together with their advantages and limitations. Toward the end, the book examines the humanized mouse model of liver-stage malaria using ectopic artificial livers regarding novel readout modalities. The recent advancement and challenges in combining liver-on-a-chip technology with biosensors are highlighted for assessing hepatocyte development viability and functions. The book elucidates the potential of these 3D models to understand the biological complexity of cellular and molecular mechanisms involved in Plasmodium development in the liver, toolboxes to investigate parasite deployment in the 3D models, and to implement in drug discovery. Finally, the book discusses the future directions and challenges in the applications of liver organoids and liver on-chip in the biology of live-stage malaria. This book is helpful for researchers and scientists in the field of parasitology, cell biology, tissue engineering, and pharmacology.
Дополнительное описание: Chapter 1_Introduction to malaria biology in a liver.- Chapter 2_Modeling a liver-stage malaria.- Chapter 3_Liver organoid and liver-on-a-chip.- Chapter 4_Generation of liver organoid.- Chapter 5_Generation of liver-on-a-chip.- Chapter 6_The use of 3D in



Complement Activation in Malaria Immunity and Pathogenesis

Автор: Stoute
Название: Complement Activation in Malaria Immunity and Pathogenesis
ISBN: 3319772570 ISBN-13(EAN): 9783319772578
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite.

Avian Malaria and Related Parasites in the Tropics: Ecology, Evolution and Systematics

Автор: Santiago-Alarcon Diego, Marzal Alfonso
Название: Avian Malaria and Related Parasites in the Tropics: Ecology, Evolution and Systematics
ISBN: 3030516350 ISBN-13(EAN): 9783030516352
Издательство: Springer
Цена: 13974.00 р.
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Описание: The Tropics are home to the greatest biodiversity in the world, but tropical species are at risk due to anthropogenic activities, mainly land use change, habitat loss, invasive species, and pathogens.

Human and Mosquito Lysozymes

Автор: Mauro Prato
Название: Human and Mosquito Lysozymes
ISBN: 3319380893 ISBN-13(EAN): 9783319380896
Издательство: Springer
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Цена: 16977.00 р.
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Описание: In addition, the emerging evidence on the involvement of human and mosquito lysozymes in malaria from available experimental models and clinical studies is thoroughly discussed, as is the potential use of other antimicrobial peptides against malaria.

Malaria: Drugs, Disease and Post-genomic Biology

Автор: David Sullivan; Sanjeev Krishna
Название: Malaria: Drugs, Disease and Post-genomic Biology
ISBN: 364206471X ISBN-13(EAN): 9783642064715
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Despite rapid increases in knowledge, malaria continues to kill more than a million people each year and causes symptomatic disease in a further 300 million individuals. This volume brings some of the world`s best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two.

Malaria

Автор: Robert M?nard
Название: Malaria
ISBN: 1493959581 ISBN-13(EAN): 9781493959587
Издательство: Springer
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Цена: 23058.00 р.
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Описание: This Methods in Molecular Biology (TM) book expands on the thorough coverage of Malaria its previous edition, offering new chapters on parasite culture methods, genome manipulation and more, and offers materials lists, protocols and troubleshooting tips.

Heat Shock Proteins of Malaria

Автор: Addmore Shonhai; Gregory L. Blatch
Название: Heat Shock Proteins of Malaria
ISBN: 9402402594 ISBN-13(EAN): 9789402402599
Издательство: Springer
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Цена: 18284.00 р.
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Описание: This book describes the role of heat shock proteins in the life cycle of malaria parasites. It examines the role of heat shock protein families from Plasmodium falciparum, their role in protein folding and in the development of malaria pathology.

Treatment and Prevention of Malaria

Автор: Henry M. Staines; Sanjeev Krishna
Название: Treatment and Prevention of Malaria
ISBN: 3034808089 ISBN-13(EAN): 9783034808088
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs.

Desert Malaria

Автор: Tyagi
Название: Desert Malaria
ISBN: 9811976929 ISBN-13(EAN): 9789811976926
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book comprehensively reviews the disease dynamics, distribution, surveillance, epidemiology, diagnosis, control strategies, and management of the desert malaria. It highlights the potential risks of unstable but often exacerbated malaria conflagration as epidemics in the middle of duned desert, a desert oasis, and desert-fringe regions. Further, it reveals the factors inveigled into desert environments due to extensive anthropogenic activities such as canalized irrigation projects, high-yielding new agriculture practices, human concentration, and increased trade. It addresses the impact of irrigation on the malarial dynamics and its coupling to the climate forcing. The book also offers a model for desert transformation into malaria heaven under the changed climatic conditions including high rainfall, humidity, and depletion in temperature. Lastly, it offers insight into malaria epidemiology and disease control in the desert’s arid environments. This book is an essential resource for medical entomologists, parasitologists, epidemiologists, and public health researchers.

Malaria

Автор: Frischknecht
Название: Malaria
ISBN: 3658384069 ISBN-13(EAN): 9783658384067
Издательство: Springer
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Цена: 3213.00 р.
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Описание: Friedrich Frischknecht gives an insight into malaria and the biological complexity of the parasites that trigger it. The author takes the reader on a journey from the historical discovery of the pathogen to the modern methods of vaccine development. He explains how genetic manipulations help to understand the parasite and to develop novel vaccination approaches. He explains the difficulties that need to be overcome to eradicate malaria. The author: Prof. Dr. Friedrich Frischknecht studied biochemistry at the Freie Universit?t Berlin and did his PhD on smallpox viruses at the European Molecular Biology Laboratory (EMBL) in Heidelberg. After a research stay at the Institut Pasteur in Paris, he has been head of a research group at the University Hospital in Heidelberg since 2005 and is interested in the molecular basis of the movement of malaria parasites.

Exploration of Host Genetic Factors associated with Malaria

Автор: Qidwai
Название: Exploration of Host Genetic Factors associated with Malaria
ISBN: 9813347635 ISBN-13(EAN): 9789813347632
Издательство: Springer
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Цена: 22359.00 р.
Наличие на складе: Нет в наличии.

Описание: This book is aimed to cover the role of genetic polymorphisms in human genes related to RBC disorders, metabolic enzymes, immune response, and cytoadherence in the susceptibility/resistance to malaria caused by Plasmodium falciparum.

Accomplishment of malaria elimination in the people`s republic of china

Название: Accomplishment of malaria elimination in the people`s republic of china
ISBN: 0323952569 ISBN-13(EAN): 9780323952569
Издательство: Elsevier Science
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Цена: 26949.00 р.
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Описание: Let`s Learn About the Forest is an interactive oversized board book that encourages little ones to use their imaginations and power of discovery to find the different animals and items in the forest God created. As they do, they will also learn interesting facts about the different animals and their habitats.

Malaria parasites

Название: Malaria parasites
ISBN: 0954246462 ISBN-13(EAN): 9780954246464
Издательство: Неизвестно
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Цена: 43362.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Based on extensive research conducted by the authors, this book is designed to help classroom teachers understand, monitor, and guide the development of students` reasoning and sense making about core ideas in elementary school mathematics. It illustrates the nature of these skills using classroom vignettes and actual student work in conjunction with instructional tasks and learning progressions.


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