Drug Delivery Strategies for Poorly Water-Soluble Drugs, Douroumis
Автор: Williams III Название: Formulating Poorly Water Soluble Drugs ISBN: 3030887189 ISBN-13(EAN): 9783030887186 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.
Автор: Williams III Название: Formulating Poorly Water Soluble Drugs ISBN: 3030887219 ISBN-13(EAN): 9783030887216 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.
Автор: Robert O. Williams III; Alan B. Watts; Dave A. Mil Название: Formulating Poorly Water Soluble Drugs ISBN: 3319826182 ISBN-13(EAN): 9783319826189 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules.
Автор: Webster Название: Poorly Soluble Drugs ISBN: 9814745456 ISBN-13(EAN): 9789814745451 Издательство: Taylor&Francis Рейтинг: Цена: 31390.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book is the first text to provide a comprehensive assessment of the application of fundamental principles of dissolution and drug release testing to poorly soluble compounds and formulations. Such drug products are, vis- -vis their physical and chemical properties, inherently incompatible with aqueous dissolution. However, dissolution methods are required for product development and selection, as well as for the fulfillment of regulatory obligations with respect to biopharmaceutical assessment and product quality understanding. The percentage of poorly soluble drugs, defined in classes 2 and 4 of the Biopharmaceutics Classification System (BCS), has significantly increased in the modern pharmaceutical development pipeline. This book provides a thorough exposition of general method development strategies for such drugs, including instrumentation and media selection, the use of compendial and non-compendial techniques in product development, and phase-appropriate approaches to dissolution development.
Emerging topics in the field of dissolution are also discussed, including biorelevant and biphasic dissolution, the use on enzymes in dissolution testing, dissolution of suspensions, and drug release of non-oral products. Of particular interest to the industrial pharmaceutical professional, a brief overview of the formulation and solubilization techniques employed in the development of BCS class 2 and 4 drugs to overcome solubility challenges is provided and is complemented by a collection of chapters that survey the approaches and considerations in developing dissolution methodologies for enabling drug delivery technologies, including nanosuspensions, lipid-based formulations, and stabilized amorphous drug formulations.
Автор: Andreas Bernkop-Schn?rch Название: Oral Delivery of Macromolecular Drugs ISBN: 1489982825 ISBN-13(EAN): 9781489982827 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an overview of the innovative oral delivery technologies that have demonstrated success in human testing. It then goes on to cite the challenges, strategies, and future trends that are to be expected.
Автор: Misra Название: Novel Drug Delivery Technologies ISBN: 9811336415 ISBN-13(EAN): 9789811336416 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: By endowing drugs with new and innovative therapeutic benefits, drug delivery systems extend products` profitable lifecycle, giving pharmaceutical companies competitive and financial advantages, and providing patients with improved medications.
Автор: Yadav, Awesh K. Название: Nano Drug Delivery Strategies For The Treatment Of Cancers ISBN: 0128197935 ISBN-13(EAN): 9780128197936 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Поставка под заказ.
Описание:
Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers.
The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field.
Автор: Hauss, David J. Название: Oral Lipid-Based Formulations ISBN: 0824729455 ISBN-13(EAN): 9780824729455 Издательство: Taylor&Francis Рейтинг: Цена: 27562.00 р. Наличие на складе: Поставка под заказ.
Автор: Robert O. Williams III; Alan B. Watts; Dave A. Mil Название: Formulating Poorly Water Soluble Drugs ISBN: 1489985921 ISBN-13(EAN): 9781489985927 Издательство: Springer Рейтинг: Цена: 32651.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights recent advancements on technologies to improve the dissolution and bioavailability of poorly water soluble drugs. It details the most current knowledge, practical methods, and regulatory considerations.
Автор: Gregory Gregoriadis; Brenda McCormack Название: Targeting of Drugs 5 ISBN: 1461379431 ISBN-13(EAN): 9781461379430 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1995
Автор: Gregory Gregoriadis; Brenda McCormack Название: Targeting of Drugs 5 ISBN: 0306455048 ISBN-13(EAN): 9780306455049 Издательство: Springer Рейтинг: Цена: 11173.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1995
Автор: Focarete, Maria Название: Core-Shell Nanostructures for Drug Delivery and Theranostics ISBN: 0081021984 ISBN-13(EAN): 9780081021989 Издательство: Elsevier Science Рейтинг: Цена: 34529.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Core-shell nanostructures for drug delivery and theranostics brings together cutting-edge research to provide detailed coverage of core-shell nanoparticles and nanofibers for drug delivery, enabling scientists and researchers to understand the latest advances and applications in this field.
The development of polymeric drug delivery systems and technologies continues to present new possibilities in terms of controlled drug release and drug targeting capabilities. Core-shell nanostructures offer many benefits, such as temporal-spatial controlled release, drug/biomolecule protection from harsh environments, and multi-drug release, and may therefore be utilized in advanced and challenging applications.
The opening part of the book deals with the fundamentals of nanotechnology for drug delivery. The second part of the book covers the recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications. The third part addresses the potential and applications of core-shell nanofiber.
This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry.
Focuses on core-shell nanoparticles and nanofiber for innovative applications, including cancer therapy, controlled release and multi-drug release
Considers future prospects and potential new applications of core-shell nanostructures for drug delivery and theranostics
Explains the principles and essential concepts of nanotechnology for drug delivery systems
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
