Advanced Delivery and Therapeutic Applications of RNAi, Cheng

Автор: Scherman Daniel
Название: Advanced Textbook On Gene Transfer, Gene Therapy And Genetic Pharmacology: Principles, Delivery And Pharmacological And Biomedical Applications Of Nucleotide-based Therapies (Second Edition)
ISBN: 1786346877 ISBN-13(EAN): 9781786346872
Издательство: World Scientific Publishing
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Цена: 33264.00 р.
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Описание:

This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.

The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.

This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.

Автор: Giovanni Melillo
Название: Hypoxia and Cancer
ISBN: 1493953559 ISBN-13(EAN): 9781493953554
Издательство: Springer
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Цена: 20896.00 р.
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Описание: ГЇВїВЅ ГЇВїВЅ ГЇВїВЅ The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues.

Автор: Keith L. March
Название: Gene Transfer in the Cardiovascular System
ISBN: 1461378818 ISBN-13(EAN): 9781461378815
Издательство: Springer
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Цена: 27950.00 р.
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Описание: a process brought about by the insertion of a gene coding for a foreign protein into target cells resulting in the synthesis of the foreign protein For gene therapy, a tmnsferred therapeutic gene must be expressed at a level beneficial for the patient.

Автор: Dmitry I. Gabrilovich; Arthur Andrew Hurwitz
Название: Tumor-Induced Immune Suppression
ISBN: 1441924000 ISBN-13(EAN): 9781441924001
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses new mechanisms that have never been discussed in a monograph before.

Автор: Giancarlo C. Folco; Bengt Samuelsson; Jacques Macl
Название: Eicosanoids
ISBN: 0306452863 ISBN-13(EAN): 9780306452864
Издательство: Springer
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Цена: 32004.00 р.
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Описание: Proceedings of a NATO ASI held in Erice, Italy, April 27-May 1, 1995.

Автор: Mouldy Sioud
Название: RNA Interference
ISBN: 1493948911 ISBN-13(EAN): 9781493948918
Издательство: Springer
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Цена: 15372.00 р.
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Описание: RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA`s unwanted effects.

Автор: Chris Maxwell; Cal Roskelley
Название: Genomic Instability and Cancer Metastasis
ISBN: 3319352954 ISBN-13(EAN): 9783319352954
Издательство: Springer
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Цена: 19589.00 р.
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Описание: Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse.

Автор: Dmitry I. Gabrilovich; Arthur Andrew Hurwitz
Название: Tumor-Induced Immune Suppression
ISBN: 1493950517 ISBN-13(EAN): 9781493950515
Издательство: Springer
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Цена: 23508.00 р.
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Описание: Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction.

Автор: Latterich, Martin
Название: RNAi
ISBN: 0415409500 ISBN-13(EAN): 9780415409506
Издательство: Taylor&Francis
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Цена: 11482.00 р.
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Автор: David O. Azorsa; Shilpi Arora
Название: High-Throughput RNAi Screening
ISBN: 149396335X ISBN-13(EAN): 9781493963355
Издательство: Springer
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Цена: 18167.00 р.
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Описание: High-throughput RNAi screening remains one of the most widely used technologies to perform target identification and validation studies in an unbiased manner. These assays are equally important for research and development across academic, biotech, and pharmaceutical industries.--

Автор: Zhang
Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells
ISBN: 1607617684 ISBN-13(EAN): 9781607617686
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.

Автор: Ronald P. van Rij
Название: Antiviral RNAi
ISBN: 1493958259 ISBN-13(EAN): 9781493958252
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Here is a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for development and optimization of RNAi-based antiviral drugs. The methods here can also be applied outside the context of a virus infection.