Описание: This book is a collection of articles by leading researchers working at the cutting edge of neuro-computational modelling of neurological and psychiatric disorders. Each article contains model validation techniques used in the context of the specific problem being studied. Validation is essential for neuro-inspired computational models to become useful tools in the understanding and treatment of disease conditions. Currently, the immense diversity in neuro-computational modelling approaches for investigating brain diseases has created the need for a structured and coordinated approach to benchmark and standardise validation methods and techniques in this field of research. This book serves as a step towards a systematic approach to validation of neuro-computational models used for studying brain diseases and should be useful for all neuro-computational modellers.
Автор: Aman B. Upaganlawar Название: Bioactive Nutraceuticals for Brain Disorders ISBN: 1536194638 ISBN-13(EAN): 9781536194630 Издательство: Nova Science Рейтинг: Цена: 32312.00 р. Наличие на складе: Невозможна поставка.
Описание: Over the past several years research concerning brain health and nutraceuticals has received much attention due to their potential neuroprotective properties and few or no side effects. Nutraceuticals exert copious effects in several biological processes, including antioxidant defences, cell proliferation and differentiation, gene expression, signal transduction, and safeguarding of mitochondrial integrity. It is very likely that the brain health of an individual is affected by his or her dietary pattern. Intake of a well-nourished diet in the earliest stages of life builds a strong foundation of the brain which helps to maintain brain health in later stages of life. On the other hand, nutritional deficiency can disrupt the structure and function of the human nervous system and increases the risk of brain disorders and early death, affecting all age groups. Although nutraceuticals are popular for health, wellbeing, and illness, the efficacy of common supplements to combat brain disorders is not clearly understood. Bioactive Nutraceuticals for Brain Disorders aims to describe the importance of nutraceutical intervention on different brain disorders to highlight the therapeutic as well as preventive potential.
Описание: This book reviews the potential effect of diet modification, lipids, and carbohydrate consumptions, vitamin supplementation, antioxidants, and nutraceuticals in the prevention and management of Alzheimer's disease. The initial chapter of the book presents the pathophysiological mechanisms, risk factors, genetic predisposition, disease diagnosis, pathology, and current treatment strategies against Alzheimer's disease. It also highlights recent developments in exploring novel compounds for the prevention and treatment of Alzheimer's disease. Subsequently, it highlights the therapeutic effect and regulation of molecular targets by natural compounds. The book discusses the potential of natural compounds in inhibiting the formation and deposition of A? peptides. It examines the natural compounds in modulating intracellular signaling molecules and enzymes involved in the pathogenesis of Alzheimer's disease. In summary, this book helps understand the role of natural compounds as a therapeutic approach in amelioration and preventing detrimental effects of Alzheimer's disease.
Автор: Muralidhara,Murali Название: Ayurvedic Herbal Preparations In Neurological Disorders ISBN: 0443190844 ISBN-13(EAN): 9780443190841 Издательство: Elsevier Science Рейтинг: Цена: 27791.00 р. Наличие на складе: Поставка под заказ.
Описание: Provides the most comprehensive coverage of the broad range of topics related to the neuroscience of aging Features sections on diagnosis and biomarkers of neurological aging, Alzheimers, and stroke Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Focuses on neurological diseases and conditions linked to aging, environmental factors, and clinical recommendations Includes more than 500 illustrations and tables
Автор: Tripathi Название: Gut Microbiome in Neurological Health and Disorders ISBN: 9811945322 ISBN-13(EAN): 9789811945328 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.
Название: Rna viruses and neurological disorders ISBN: 1032259566 ISBN-13(EAN): 9781032259567 Издательство: Taylor&Francis Рейтинг: Цена: 9951.00 р. Наличие на складе: Поставка под заказ.
Описание: This book provides an outline of epigenetics as a whole, while also specifically examining a range of epigenetic players, including histone acetyl transferases (HATs) and histone deacetylases (HDACs). It chiefly focuses on the emerging targets of HDACs and their implications for various neurological disorders, while also discussing the drawbacks of current therapeutic strategies, the classification of HDAC inhibitors, and their promising effects in connection with specific neurological disorders. The book explores the potential use of these inhibitors as novel therapeutic agents, considers the current challenges involved in using them to tackle neurological complications, and offers a novel solution by designing isoform-selective inhibitors and employing combinatorial therapeutic strategies. Its final section, which explores future directions, elaborates on the possibility of enhancing HDAC inhibitors’ therapeutic efficacy against various neurological complications.
Название: Modern cns drug discovery ISBN: 3030623505 ISBN-13(EAN): 9783030623500 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system.
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