Respiratory Delivery of Biologics, Nucleic Acids, and Vaccines, Lam
Автор: Caffrey Название: Parasitic Helminths: Targets, Screens, Drugs and Vaccines ISBN: 3527330593 ISBN-13(EAN): 9783527330591 Издательство: Wiley Рейтинг: Цена: 12856.00 р. 18366.00-30% Наличие на складе: Есть (1 шт.) Описание: The first title dealing with drug discovery against parasitic worms (Helminths) which include many of the major human and animal parasites. The book focusses on the development of novel drugs and vaccination strategies making it attractive for academia and industry alike.
Автор: Amine Kamen, Laura Cervera Название: Bioprocessing of Viral Vaccines ISBN: 1032132116 ISBN-13(EAN): 9781032132112 Издательство: Taylor&Francis Рейтинг: Цена: 22202.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines.
Автор: Madkour, Loutfy H. Название: Nanoparticle-Based Drug Delivery in Cancer Treatment ISBN: 1032135204 ISBN-13(EAN): 9781032135205 Издательство: Taylor&Francis Рейтинг: Цена: 33686.00 р. Наличие на складе: Поставка под заказ.
Автор: Dushyant Varshney; Manmohan Singh Название: Lyophilized Biologics and Vaccines ISBN: 149392382X ISBN-13(EAN): 9781493923823 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface.- Part I - Lyophilization History and Fundamentals.- History of Lyophilization.- Heterogeneity of protein environments in frozen solutions and in the dried state.- Advance understanding of buffer behavior during lyophilization.- Advances in Instrumental Analysis Applied to the Development of Lyophilization Cycles.- New Developments in Controlled Nucleation: Commercializing VERISEQ(R) Nucleation technology.- Part II - Lyophilized Biologics and Vaccines - Modality Considerations.- Lyophilized Biologics.- Lyophilization of Therapeutic Proteins in Vials - Process Scale-up and Advances in Quality by Design.- Advances in Process Analytical Technology in Freeze Drying.- Process Scale-up and Optimization of Lyophilized Vaccine Products.- Stabilization of Plasmid DNA and Lipid-based Therapeutics as Dehydrated Formulations.- Part III - Advances in Alternate Drying.- Alternatives to Vial Lyophilization.- Spray Drying of Biopharmaceuticals.- Current Trends and Advances in Bulk Crystallization and Freeze Drying of Biopharmaceuticals.- Case Studies and Examples of Biopharmaceutical Modalities.- Processed by Bulk Crystallization or Bulk Freeze Drying.- Part IV- Regulatory, Packaging and Technology Transfer Considerations.- Lyophilization of Biologics - An FDA Perspective.- Recent Trends in Lyophilized Delivery Devices and Packaging.- Lyophilization Technology Transfer towards Product Launch.
Автор: Dushyant Varshney; Manmohan Singh Название: Lyophilized Biologics and Vaccines ISBN: 1493955683 ISBN-13(EAN): 9781493955688 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide the reader through all crucial aspects, from biophysical and chemical stability considerations of proteins, analytical methods, advances in controlled ice nucleation and quality-by-design approaches, alternate drying technology, to latest regulatory, packaging and technology transfer considerations to develop a stable, safe and effective therapeutic protein, vaccine and biotechnology products. Lyophilized Biologics and Vaccines: Modality-Based Approaches is composed of four sections with a total of 17 chapters. It serves as a reference to all critical assessments and steps from early pre-formulation stages to product launch: * Provides recent understanding of heterogeneity of protein environment and selection of appropriate buffer for stabilization of lyophilized formulations * Details the latest developments in instrumental analysis and controlled ice nucleation technology * Explains in-depth lyophilized (or dehydrated) formulation strategies considering diverse modalities of biologics and vaccines, including plasmid DNA and lipid-based therapeutics * Details an exhaustive update on quality-by-design and process analytical technology approaches, illustrated superbly by case studies and FDA perspective * Provides the latest detailed account of alternate drying technologies including spray drying, bulk freeze-drying and crystallization, supported exceptionally by case studies * Provides a step-by-step guide through critical considerations during process scale-up, technology transfer, packaging and drug delivery device selection, for a successful lyophilization process validation, regulatory submission and product launch Chapters are written by one or more world-renowned leading authorities from academia, industry or regulatory agencies, whose expertise cover lyophilization of the diverse modalities of biopharmaceuticals. Their contributions are based on the exhaustive review of literature coupled with excellent hands-on experiences in laboratory or GMP setup, making this an exceptional guide to all stages of lyophilized or dehydrated product development.
Автор: Muttil Pavan, Kunda Nitesh K. Название: Mucosal Delivery of Drugs and Biologics in Nanoparticles ISBN: 3030359123 ISBN-13(EAN): 9783030359126 Издательство: Springer Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It provides an overview of nanotechnology in drug delivery with a description of different types of nanoparticles, methods of preparation and characterization, and functionalization for site-specific drug delivery.
Описание: Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure.
Автор: Madkour Loutfy H. Название: RNA Delivery Function for Anticancer Therapeutics ISBN: 1032135166 ISBN-13(EAN): 9781032135168 Издательство: Taylor&Francis Рейтинг: Цена: 28327.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the status of clinical trials related to siRNA-based cancer therapy, as well as the remaining issues that need to be overcome to establish a successful therapy. It, then introduces various promising design strategies of delivery vehicles for stable and targeted siRNA delivery, including the prospects for future design.
Автор: Muttil Pavan, Kunda Nitesh K. Название: Mucosal Delivery of Drugs and Biologics in Nanoparticles ISBN: 3030359093 ISBN-13(EAN): 9783030359096 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It provides an overview of nanotechnology in drug delivery with a description of different types of nanoparticles, methods of preparation and characterization, and functionalization for site-specific drug delivery.
Автор: Jones, Byron Patterson, Scott D. (Pfizer Vaccines Clinical Research & Development, Collegeville, Pennsylvania, USA) Название: Bioequivalence and Statistics in Clinical Pharmacology ISBN: 0367782448 ISBN-13(EAN): 9780367782443 Издательство: Taylor&Francis Рейтинг: Цена: 7348.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and interpret bioequivalence trials; explor
