Название: MicroRNA Profiling in Cancer ISBN: 9814267015 ISBN-13(EAN): 9789814267014 Издательство: Taylor&Francis Рейтинг: Цена: 15004.00 р. Наличие на складе: Нет в наличии.
Автор: Bright, Jo-Anne Coble, Michael Название: Forensic DNA Profiling ISBN: 1032082313 ISBN-13(EAN): 9781032082318 Издательство: Taylor&Francis Рейтинг: Цена: 7501.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Forensic DNA Profiling is a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a Likelihood Ratio, and how to use the subsequent Likelihood Ratio when reporting interpretation conclusions.
Автор: Chun, Julia Tingley, Tyler Lidwell, William Название: Law, Practice and Politics of Forensic DNA Profiling ISBN: 0367338491 ISBN-13(EAN): 9780367338497 Издательство: Taylor&Francis Рейтинг: Цена: 19906.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This collection reviews developments in DNA profiling across jurisdictions with a focus on scientific and technological advancement as well as the political and socio-legal impact.
Название: Risk Profiling in Genomics ISBN: 0367356694 ISBN-13(EAN): 9780367356699 Издательство: Taylor&Francis Рейтинг: Цена: 22202.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume presents the ethical implications of risk information as related to genetics and other health data for policy decisions at clinical, research and societal levels. It will be of great interest to students and scholars of theoretical and clinical medical ethics, medical sociology, risk communication and ethics of risk.
Название: Transcriptome profiling ISBN: 0323918107 ISBN-13(EAN): 9780323918107 Издательство: Elsevier Science Рейтинг: Цена: 19370.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This all-new Pathfinder (R) Guide covers two stunning island destinations in one unique volume - In Orkney, eight walks feature on the largest island, Mainland, with another six located on Hoy, Rousay and South Ronaldsay. In Shetland, seven routes explore Mainland, with seven more rambles on Bressay, Mousa, St Ninian`s Isle, Unst, West Burra and Y
Автор: Dash Название: Handbook of DNA Profiling ISBN: 9811643172 ISBN-13(EAN): 9789811643170 Издательство: Springer Рейтинг: Цена: 83852.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This reference book comprehensively reviews the significance of DNA technology in forensic science. After presenting the theory, basic principles, tools and techniques that are used in forensic DNA typing, it summarizes various techniques, including autosomal STR, Y-STR, X-STR, mitochondrial DNA and NGS, used in solving both criminal as and civil cases, such as paternity disputes, identification of mutilated remains, and culprit identification in sexual assault and murder cases. It also provides an overview of DNA-based genetic diagnostics for various diseases, and discusses the role of DNA typing in drug reactions, as well as the application of non-human DNA profiling of animals and plants in forensic science investigations. Lastly, the book examines the role of internal quality control in maintaining the high quality of DNA profiling.
Автор: Mathias Munschauer Название: High-Resolution Profiling of Protein-RNA Interactions ISBN: 3319162527 ISBN-13(EAN): 9783319162522 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The work reported in this book represents an excellent example of how creative experimentation and technology development, complemented by computational data analysis, can yield important insights that further our understanding of biological entities from a systems perspective. The book describes how the study of a single RNA-binding protein and its interaction sites led to the development of the novel ‘protein occupancy profiling’ technology that for the first time captured the mRNA sequence space contacted by the ensemble of expressed RNA binders. Application of protein occupancy profiling to eukaryotic cells revealed that extensive sequence stretches in 3’ UTRs can be contacted by RBPs and that evolutionary conservation as well as negative selection act on protein-RNA contact sites, suggesting functional importance. Comparative analysis of the RBP-bound sequence space has the potential to unravel putative cis-acting RNA elements without a priori knowledge of the bound regulators. Here, Dr. Munschauer provides a comprehensive introduction to the field of post-transcriptional gene regulation, examines state-of-the-art technologies, and combines the conclusions from several journal articles into a coherent and logical story from the frontiers of systems-biology inspired life science. This thesis, submitted to the Department of Biology, Chemistry and Pharmacy at Freie Universit?t Berlin, was selected as outstanding work by the Berlin Institute for Medical Systems Biology at the Max-Delbrueck Center for Molecular Medicine, Germany.
Автор: J?rg Epplen; Thomas Lubjuhnn Название: DNA Profiling and DNA Fingerprinting ISBN: 3764360186 ISBN-13(EAN): 9783764360184 Издательство: Springer Рейтинг: Цена: 13060.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text reflects practical approaches to answering a variety of biological and medical questions, using DNA fingerprinting and genetic profiling in a broad sense that also includes statistical evaluation of the data. The book is aimed at students as well as academic teachers and researchers.
Автор: Zhang Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 1607617684 ISBN-13(EAN): 9781607617686 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.
Название: Regulatory microRNA ISBN: 3038977683 ISBN-13(EAN): 9783038977681 Издательство: Неизвестно Рейтинг: Цена: 11918.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book includes updated information about microRNA regulation, for example, in the fields of circular RNAs, multiomics analysis, biomarkers and oncogenes. The variety of topics included in this book reaffirms the extent to which microRNA regulation affects biological processes. Although microRNAs are not translated to proteins, their importance for biological processes is not less than proteins. An understanding of their roles in various biological processes is critical to understanding gene function in these biological processes. Although non-coding RNAs other than microRNAs have recently come under investigation, microRNA still remains the front runner as the subject of genetic and biological studies. In reading the collection of papers, readers can grasp the most updated information regarding microRNA regulation, which will continue to be an important topic in genetics and biology.
Автор: Mettinger Название: Exosomes, Stem Cells and MicroRNA ISBN: 3319744690 ISBN-13(EAN): 9783319744698 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.
Автор: Baohong Zhang; Edmund J. Stellwag Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 149395749X ISBN-13(EAN): 9781493957491 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent stem cell research has revealed that miRNA and RNAi-mediated gene regulation is one of the vital determinates controlling the state of cell differentiation, with the small RNAs serving as key elements involved in regulatory network control of pluripotent cell fate determination. In RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications, expert authors from laboratories across the globe contribute an accessible compendium of up-to-date, proven methods focused on the study of the titular topic. Divided into three sections, the book first gives a brief introduction to RNAi and miRNAs in stem cells, with a focus on the current status of research and future perspectives, then it continues with detailed methods and protocols for RNAi screening, transfection, and the knockdown of specific genes and pathways in several animal species, including humans and mice, concluding with a section on recently developed methods for identification of miRNAs, including a general protocol for preparation and analysis of miRNA libraries for deep sequencing, knock down of a specific gene using miRNA-based shRNA, and miRNA expression analysis using qRT-PCR. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes highlighting tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications serves as a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and the exciting areas of medicine, including regenerative medicine, aging, cancer, and neurological disorders, that can be advanced through this expanding area of research.
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