Adaptive Design Theory and Implementation Using SAS and R,
Старое издание
Автор: Chang, Mark Название: Adaptive design theory and implementation using sas and r ISBN: 1584889624 ISBN-13(EAN): 9781584889625 Издательство: Taylor&Francis Цена: 8879.00 р. Наличие на складе: Поставка под заказ. Описание: Adaptive design has become an important tool in modern pharmaceutical research and development. This book provides a concise, unified presentation of adaptive design theories, uses SAS and R for the design and simulation of adaptive trials, and illustrates how to master different adaptive designs through real-world examples.
Название: Injectable Dispersed Systems ISBN: 0367392828 ISBN-13(EAN): 9780367392826 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This authoritative guide is the most current source on the design and manufacturing of parenteral dispersed systems. It showcases the utility of dispersed systems in drug delivery, drug targeting, and pharmaceutical engineering. It covers the fundamental physicochemical and biopharmaceutical principles governing dispersed systems, illustrates the application of dispersed systems technology to current challenges in drug formulation and processing, and helps readers select the most appropriate delivery system according to performance characteristics and route of administration
For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for implementing preferred gas and liquid chromatographic methods, Advances in Chromatographic Techniques for Therapeutic Drug Monitoring is a comprehensive reference describing the theory and application of therapeutic drug monitoring in clinical laboratories.
Edited by a distinguished authority in the field and containing contributions from a variety of experts, the book discusses preanalytical variables, the pitfalls of immunoassays, tandem mass spectrometry, issues related to pain management and herbal supplements, and therapeutic drug monitoring for a range of medications, including:
Anticonvulsants
Digitalis
Cardioactive drugs
Antidepressants
Immunosuppressants
Anti-cancer drugs
Vancomycin and aminoglycosides
Antibiotics
Antiretroviral drugs
Nonnarcotic analgesics
Anti-inflammatory drugs
Examing older and newer drugs, the book contains detailed discussions on the rationale for therapeutic drug monitoring of each class of drugs, along with their basic pharmacology and toxicology. An extensive list of references is provided at the end of each chapter so that those interested in implementing a new drug assay can find the most appropriate method for the intended drug.
Название: Nanomedicine in Drug Delivery ISBN: 1138072613 ISBN-13(EAN): 9781138072619 Издательство: Taylor&Francis Рейтинг: Цена: 12554.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
There is a clear need for innovative technologies to improve the delivery of therapeutic and diagnostic agents in the body. Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit while limiting unwanted side effects. Nanomedicine in Drug Delivery gives an overview of aspects of nanomedicine to help readers design and develop novel drug delivery systems and devices that build on nanoscale technologies.
Featuring contributions by leading researchers from around the world, the book examines:
The integration of nanoparticles with therapeutic agents
The synthesis and characterization of nanoencapsulated drug particles
Targeted pulmonary nanomedicine delivery using inhalation aerosols
The use of biological systems--bacteria, cells, viruses, and virus-like particles--as carriers to deliver nanoparticles
Nanodermatology and the role of nanotechnology in the diagnosis and treatment of skin disease
Nanoparticles for the delivery of small molecules, such as for gene and vaccine delivery
The use of nanotechnologies to modulate and modify wound healing
Nanoparticles in bioimaging, including magnetic resonance, computed tomography, and molecular imaging
Nanoparticles to enhance the efficiency of existing anticancer drugs
The development of nanoparticle formulations
Nanoparticles for ocular drug delivery
Nanoparticle toxicity, including routes of exposure and mechanisms of toxicity
The use of animal and cellular models in nanoparticles safety studies
With its practical focus on the design, synthesis, and application of nanomedicine in drug delivery, this book is a valuable resource for clinical researchers and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner. It explores a wide range of promising approaches for the diagnosis and treatment of diseases using cutting-edge nanotechnologies.
Автор: Teasdale Название: ICH Quality Guidelines: An Implementation Guide ISBN: 1118971116 ISBN-13(EAN): 9781118971116 Издательство: Wiley Рейтинг: Цена: 45770.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Examining the implications and practical implementation of multi-disciplinary International Conference on Harmonization (ICH) topics, this book gives an integrated view of how the guidelines inform drug development strategic planning and decision-making, together with impact on marketed products.
Автор: Mahato Название: Pharmaceutical Dosage Forms & Drug ISBN: 1482253623 ISBN-13(EAN): 9781482253627 Издательство: Taylor&Francis Рейтинг: Цена: 18374.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Completely revised and updated, this third edition of Pharmaceutical Dosage Forms and Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery - including emerging new biotechnology-based treatment modalities.
Название: Biological And Pharmaceutical Appli ISBN: 1482250160 ISBN-13(EAN): 9781482250169 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Biological and Pharmaceutical Applications of Nanomaterials presents the findings of cutting-edge research activities in the field of nanomaterials, with a particular emphasis on biological and pharmaceutical applications. Divided into four sections--nanomaterials for drug delivery, antimicrobial nanomaterials, nanomaterials in biosensors, and safety of nanomaterials--this book:
Covers topics such as stimuli-responsive nanostructured silica matrixes, gold nanoparticles, and liposomes for targeting drug delivery and dental applications
Describes the use of nanocarriers and nanoparticles as cancer and peptide therapeutics, the influence of surface characteristics on microbial adhesion, and the latest developments in antimicrobial nanostructured polymers for medical applications
Discusses recent advances in nanodiagnostic techniques for infectious agents, chromogenic biosensors for pathogen detection, electrochemical biosensors for detecting DNA damage and genotoxicity, and molecular imaging with quantum dots including surface modifications by polymers for biosensing applications
Featuring contributions from field experts and researchers in industry and academia, Biological and Pharmaceutical Applications of Nanomaterials provides state-of-the-art information on nanomaterials and their use in drug delivery, infection control, and biomedicine.
Автор: Dykman, Lev , Khlebtsov, Nikolai Название: Gold Nanoparticles in Biomedical Applications ISBN: 0367892219 ISBN-13(EAN): 9780367892210 Издательство: Taylor&Francis Рейтинг: Цена: 11176.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Functionalized gold nanoparticles (GNPs) with controlled geometrical, optical, and surface chemistry properties are the subject of intensive studies and applications in biology and medicine. The efficiency of biomedical applications of functionalized GNPs in therapy and diagnostics is determined by their intrinsic physiochemical parameters and b
Название: Nanoparticulate Drug Delivery Systems ISBN: 0367453118 ISBN-13(EAN): 9780367453114 Издательство: Taylor&Francis Рейтинг: Цена: 9492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS-- including lipid nanoparticles for dermal applications; nanocarriers for the treatment of restenosis; and for ocular, central nervous system, and gastrointestinal applications. It also explores its use as an adjuvant for vaccine development.
Supplying insight from international experts, this guide
Discusses formulation for poorly soluble drugs
Presents biological requirements for nanotherapeutic applications
Demonstrates the role of nanobiotechnology in the development of nanomedicine
Documents recent advances in nanoparticulate technology--including electrospining, formation of microcrystals, and production of liquid crystalline phases
Examines the technology of metallic nanoparticles
Название: Multiparticulate Oral Drug Delivery ISBN: 0367402041 ISBN-13(EAN): 9780367402044 Издательство: Taylor&Francis Рейтинг: Цена: 6736.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This definitive reference explores the various aspects of multiparticulate dosage form development-assessing the in vivo behavior and performance of multiparticulates as well as comparing their market position to other dosage forms. Discussing-for the first time in a comprehensive manner-alternative pelletization techniques such as balling (spherical agglomeration), spray congealing, and cryopelletization, Multiparticulate Oral Drug Delivery
describes formulation and processing variables that affect the formation, integrity, and performance of coatings derived from molten materials and polymeric solutions and dispersions
analyzes the biopharmaceutical aspects and in vivo performance of multiparticulate drug delivery systems
details the idiosyncrasies of the manufacturing process of hard-shell gelatin capsules
explains the different kinds of packaging materials and machinery and the importance of packaging during the development phase and beyond
previews the marketing considerations of multiparticulate systems in the years to come
presents practical solutions to problems encountered in the area of film-coating processes
and more!
Название: Treatise on Controlled Drug Delivery ISBN: 0367402939 ISBN-13(EAN): 9780367402938 Издательство: Taylor&Francis Рейтинг: Цена: 9492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An introductory but detailed treatise which includes some 1,000 references and solved examples and end-of-chapter problems, making it useful to both students and practitioners. The pharmokinetics, pharmacodynamics, and biological and biopharmaceutical parameters pertinent to each route of administra
Название: Colloids In Drug Delivery ISBN: 113819915X ISBN-13(EAN): 9781138199156 Издательство: Taylor&Francis Рейтинг: Цена: 10717.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles the work of 65 of the world's leading colloid scientists who examine the full spectrum of this rapidly emerging science, from pure to applied, most of it drawn from their own experience and research.
The book begins by examining the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds, and their use in drug delivery and biotechnology. It examines the development of controlled and targeted delivery systems by utilizing the various properties of colloids before moving on to discuss various applications and fields of research.
Topics discussed include:
The use of hard, soft, and macromolecular colloidal drug delivery systems formed by surfactants, polymers, proteins, and lipids
Recent advances in procolloidal systems, self-emulsifying drug delivery systems, and aerosol applications to pharmaceutical drug delivery
Colloidal nanocarriers for imaging applications and the treatment of dental and periodontal diseases
Classification and application of colloidal drug delivery systems in tumor targeting
The use of colloids for improved nasal, ocular, vaginal, oral, buccal, gastrointestinal, and colon drug delivery
Examining topics necessary to the critical evaluation of a drug candidate's potential for delivery, the book also describes the preparation, classification, interfacial activity, surface modifications and influence on particle characteristics, drug delivery, and drug targeting. Each chapter in this expansive volume explains why a particular system is used for the intended application, how it is made, and how it behaves.
All those concerned with the research, development, and manufacture of drugs will find this a valuable reference, offering a wealth of research upon which they can build.
Название: Sustained-Release Injectable Products ISBN: 036739877X ISBN-13(EAN): 9780367398774 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Sustained-Release Injectable Products focuses on the development process for sustained-release versions of drugs and delivery systems and administration routes. From the rationale and basic product development principles to regulatory issues and the approval process, expert contributors address virtually every aspect. They bring together common threads that apply to any sustained-release formulation, such as scale-up, safety, biocompatibility, analytical challenges, and quality assurance.
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