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Microbiological Assay for Pharmaceutical Analysis, Hewitt



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Цена: 53543р.
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Автор: Hewitt
Название:  Microbiological Assay for Pharmaceutical Analysis
Перевод названия: Микробиологическое испытание для фармацевтического анализа
ISBN: 9780849318245
Издательство: Taylor&Francis
Классификация:
ISBN-10: 0849318246
Обложка/Формат: Hardback
Страницы: 260
Вес: 0.514 кг.
Дата издания: December 16, 2003
Язык: English
Иллюстрации: 49 black & white illustrations, 114 black & white tables
Размер: 244 x 166 x 21
Читательская аудитория: Tertiary education (us: college)
Подзаголовок: A rational approach
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Дополнительное описание: Кол-во стр.: 260
Формат: 235 x 159 x 19
Дата издания: 2003
Страна: UK
Круг читателей: general; academic, specialist; research, professional
Иллюстрации: Illustrations
Вес: 499





Design and Analysis of Quality of Life Studies in Clinical Trials

Автор: Fairclough
Название: Design and Analysis of Quality of Life Studies in Clinical Trials
ISBN: 1584882638 ISBN-13(EAN): 9781584882633
Издательство: Taylor&Francis
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Цена: р.
Наличие на складе: Невозможна поставка.

Описание: Clinical trials often include the evaluation of Health-Related Quality of Life (HRQoL), yet many investigators remain unaware of the unique measurement and analysis issues associated with the assessment of HRQoL. Focusing on the specific features of QoL data, this book details the relevant issues and presents a range of solutions. Written from the author's extensive experience in the field, it includes SAS and S-PLUS programs, checklists, figures, and a clear presentation that combine to provide readers with the tools and skills they need to design, conduct, analyze, and report their own studies.

Introduction to Pharmaceutical Chemical Analysis

Автор: Hansen
Название: Introduction to Pharmaceutical Chemical Analysis
ISBN: 0470661224 ISBN-13(EAN): 9780470661222
Издательство: Wiley
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Цена: 7977 р.
Наличие на складе: Поставка под заказ.

Описание: This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide.

Introduction to Pharmaceutical Chemical Analysis

Автор: Hansen
Название: Introduction to Pharmaceutical Chemical Analysis
ISBN: 0470661216 ISBN-13(EAN): 9780470661215
Издательство: Wiley
Рейтинг:
Цена: 24321 р.
Наличие на складе: Поставка под заказ.

Описание: This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide.

Handbook of Modern Pharmaceutical Analysis,3

Автор: Satinder Ahuja
Название: Handbook of Modern Pharmaceutical Analysis,3
ISBN: 0120455552 ISBN-13(EAN): 9780120455553
Издательство: Elsevier Science
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Цена: 30443 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This text describes the role modern pharmaceutical analysis plays in the development of new drugs. It discusses the techniques of discovering new drugs and developing convential and new dosage forms, and how analytical methods are developed and selected for assuring the quality of drug products.

Collins and Lyne`s Microbiological Methods. 8 ed

Автор: Collins
Название: Collins and Lyne`s Microbiological Methods. 8 ed
ISBN: 0340808969 ISBN-13(EAN): 9780340808962
Издательство: Hodder Arnold
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Цена: 10845 р.
Наличие на складе: Нет в наличии.

Описание: This fully revised eighth edition of the classic bench book is a guide to microbiological techniques covering clinical, food and drink, and environmental and veterinary specimens. The rapid progress in microbiology is reflected in additnal notes and chapters, and a revised page design also provides the reader with easy access to the most important information. DNA techniques - the most advanced in microbiological methods - are covered and an expanded chapter on mycology and immudiagnostics features. Text icons and summary boxes highlight useful information. This text includes information on the medium in which the bacteria breed, as well as the methods involved.

Statistical Aspects of the Microbiological Examination of Foods

Автор: Jarvis, Basil
Название: Statistical Aspects of the Microbiological Examination of Foods
ISBN: 0128039736 ISBN-13(EAN): 9780128039731
Издательство: Elsevier Science
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Цена: 9645 р.
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Описание: Statistical Aspects of the Microbiological Examination of Foods, Third Edition, updates some important statistical procedures following intensive collaborative work by many experts in microbiology and statistics, and corrects typographic and other errors present in the previous edition. Following a brief introduction to the subject, basic statistical concepts and procedures are described including both theoretical and actual frequency distributions that are associated with the occurrence of microorganisms in foods. This leads into a discussion of the methods for examination of foods and the sources of statistical and practical errors associated with the methods. Such errors are important in understanding the principles of measurement uncertainty as applied to microbiological data and the approaches to determination of uncertainty. . The ways in which the concept of statistical process control developed many years ago to improve commercial manufacturing processes can be applied to microbiological examination in the laboratory. This is important in ensuring that laboratory results reflect, as precisely as possible, the microbiological status of manufactured products through the concept and practice of laboratory accreditation and proficiency testing. The use of properly validated standard methods of testing and the verification of ‘in house’ methods against internationally validated methods is of increasing importance in ensuring that laboratory results are meaningful in relation to development of and compliance with established microbiological criteria for foods. . The final chapter of the book reviews the uses of such criteria in relation to the development of and compliance with food safety objectives. Throughout the book the theoretical concepts are illustrated in worked examples using real data obtained in the examination of foods and in research studies concerned with food safety.

Drug Discovery and Evaluation / Pharmacological Assays

Автор: Vogel Hans G.
Название: Drug Discovery and Evaluation / Pharmacological Assays
ISBN: 3540714200 ISBN-13(EAN): 9783540714200
Издательство: Springer
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Цена: 88952 р.
Наличие на складе: Поставка под заказ.

Описание: Offering both cutting-edge and classic pharmacological methods, this new edition to a successful reference offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs.

Drug Discovery and Evaluation / Pharmacological Assays

Автор: Vogel Hans G.
Название: Drug Discovery and Evaluation / Pharmacological Assays
ISBN: 3540298371 ISBN-13(EAN): 9783540298373
Издательство: Springer
Цена: 23753 р.
Наличие на складе: Поставка под заказ.

Описание: Now expanded and updated to include molecular biology and genetic engineering techniques! The 2nd edition of this successful reference book contains a comprehensive selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic respiratory, renal and immunomodulatory activities. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. The enclosed and fully searchable CD-ROM allows easy identification of specific tests. An appendix with up-to-date guidelines and legal regulations for animal experiments in various countries will help the reader to plan experiments more effectively.

Clinical Antimicrobial Assays (Paperback)

Автор: Reeves, D. S.; Wise, R.; Andrews, J. M .; White, L
Название: Clinical Antimicrobial Assays (Paperback)
ISBN: 0199223254 ISBN-13(EAN): 9780199223251
Издательство: Oxford Academ
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Цена: 6327 р.
Наличие на складе: Поставка под заказ.

Описание: In 1978 the forerunner of this book appeared as "Laboratory Methods in Antimicrobial Therapy" (Editors Reeves, Philips, Williams and Wise). This long awaited new volume comprises 19 chapters relevant to the subject of assays and pharmacology of antimicrobials.

High-Throughput Screening Assays in Toxicology

Автор: Zhu
Название: High-Throughput Screening Assays in Toxicology
ISBN: 1493963449 ISBN-13(EAN): 9781493963447
Издательство: Springer
Рейтинг:
Цена: 19304 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book focuses on recently developed High Throughput Screening (HTS) assay protocols, many involved in the ToxCast and/or Tox21 initiatives, and the relevant HTS data analysis techniques. Divided into three sections, in vitro assays, in vivo assays, and computational techniques to analyze HTS data are all examined. Written for the highly successful Methods in Molecular Biology series, most chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, High Throughput Screening Assays in Toxicology serves as a valuable reference resource for translating new HTS techniques into standardized chemical toxicity assessment tools in order to advance modern toxicology research to a new era where HTS techniques can partially replace the prevailing animal models.
Handbook of Modern Pharmaceutical Analysis,10

Автор: Satinder Ahuja
Название: Handbook of Modern Pharmaceutical Analysis,10
ISBN: 0123756804 ISBN-13(EAN): 9780123756800
Издательство: Elsevier Science
Рейтинг:
Цена: 29700 р.
Наличие на складе: Поставка под заказ.

Описание: Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use.

  • Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it
  • Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations
  • Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays

Автор: Vogel
Название: Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
ISBN: 3642252397 ISBN-13(EAN): 9783642252396
Издательство: Springer
Рейтинг:
Цена: 103949 р.
Наличие на складе: Невозможна поставка.

Описание: Safety aspects have become an outstanding issue in the process of drug discovery and development. Until 15 years ago safety aspects were addressed by pharmacological testing of the selected compound in high doses in tests directed at indications other than the intended indication of the new compound. These tests were followed by pharmacokinetic studies, which were mainly aimed at confirming of a suitable half-life time and at oral activity. Safety aspects relied mostly on toxicity studies, which however gave information on changes of organ structure rather than on organ function. Toxicological and pharmacokinetic studies were adapted to the progress of studies in clinical pharmacology and clinical trails. But the success rate in the pharmaceutical industry and the introduction of new chemical entities to the market per year dropped dramatically, whereas the development time for a new compound increased, sometimes exceeding the patent protection. A change of strategy was therefore adopted, involving the following changes: -          Parallel instead of sequential involvement of the various disciplines (multidimensional compound optimization).-          The term Safety Pharmacology was coined. The International Conference on Harmonization (ICH) founded a Safety Pharmacology Working Group. Easily accessible and the most informative tests now have to be selected.-          Exposure of a drug to the body by pharmacokinetic studies on absorption, distribution, metabolism and excretion has to be investigated at an early stage of development and can contribute to the selection of a compound for development. Toxicology experienced major achievements by the introduction of new methods, e.g., in silico methods, toxicogenomics and toxicoproteomics.The book is a landmark in the continuously changing world of drugs. As such it is important reading for many groups: not only for all students of pharmacology and toxicology but also for physicians, especially those involved in clinical trials of drugs, and for pharmacists who have to know the safety requirements of drugs.The book is absolutely essential for scientists and managers in the pharmaceutical industry who are involved in drug finding, drug development and decision making in the development process.In particular, the book will be of use for government institutions and committees working on official guidelines for drug evaluation worldwide.


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