Biology and treatment of retinoblastoma, Carlos Rodriguez-Galindo (Ed.)

Автор: Jasmine H. Francis; David H. Abramson
Название: Recent Advances in Retinoblastoma Treatment
ISBN: 3319194666 ISBN-13(EAN): 9783319194660
Издательство: Springer
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Цена: 16769.00 р.
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Описание: It addresses all the essential aspects of retinoblastoma and its management, including: its molecular biology and genetics, management by focal treatment, intraarterial and intravitreal chemotherapy, electroretinogram monitoring of treatment, pharmacokinetic studies, high-risk features, treatment of metastatic disease, and long-term follow-up.

Автор: Pearson Fergus
Название: Retinoblastoma: A Detailed Study of Tumor Suppressor Gene
ISBN: 1632423596 ISBN-13(EAN): 9781632423597
Издательство: Неизвестно
Цена: 14476.00 р.
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Автор: Pedro G. Santiago-Cardona
Название: The Retinoblastoma Protein
ISBN: 1493975641 ISBN-13(EAN): 9781493975648
Издательство: Springer
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Цена: 16769.00 р.
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Описание:

This volume covers the mechanisms of pRb inactivation detailing repressive mechanisms commonly associated to cancer, and representative of the experimentally relevant tests used in the establishment of cancer diagnosis and prognosis. Chapters contain protocols and in-depth discussions for commonly used experimental approaches to assess the status and function of components of the pRb pathway, including pRb itself, in cell lines and biological samples.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, The Retinoblastoma Protein aims to serve as a guide to assist molecular cancer biologists in their search for understanding of the molecular functions of this preeminent tumor suppressor.

Автор: Matthew W. Wilson
Название: Retinoblastoma
ISBN: 1489977538 ISBN-13(EAN): 9781489977533
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Although rare, retinoblastoma has been at the fore- fortunate; while in the developed world eye preser- front of cancer research and treatment for the last tion has become a priority, developing countries c- three decades. The two-hit hypothesis of oncogenesis tinue to face delays in diagnosis, poor access to care, proposed by Alfred Knudson provided the conceptual and suboptimal treatment – the problem in the less framework for tumor suppressor gene research and developed world is cure. led to the discovery of the retinoblastoma pathway as In this book, we have invited a team of experts to a key element in cancer development. More recently, address all those important aspects of retinoblastoma the treatment of children with retinoblastoma has also research and therapy - from biology to epidemiology provided a model for modern approach to the can- to treatment. We hope that in subsequent editions we cer patient; state of the art retinoblastoma treatment will be able to continue to provide updates on such can only be conceived in the context of the multidis- exciting subjects.