Retinoblastoma, Matthew W. Wilson

Автор: Pedro G. Santiago-Cardona
Название: The Retinoblastoma Protein
ISBN: 1493975641 ISBN-13(EAN): 9781493975648
Издательство: Springer
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Цена: 16769.00 р.
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Описание:

This volume covers the mechanisms of pRb inactivation detailing repressive mechanisms commonly associated to cancer, and representative of the experimentally relevant tests used in the establishment of cancer diagnosis and prognosis. Chapters contain protocols and in-depth discussions for commonly used experimental approaches to assess the status and function of components of the pRb pathway, including pRb itself, in cell lines and biological samples.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, The Retinoblastoma Protein aims to serve as a guide to assist molecular cancer biologists in their search for understanding of the molecular functions of this preeminent tumor suppressor.

Автор: Carlos Rodriguez-Galindo (Ed.)
Название: Biology and treatment of retinoblastoma
ISBN: 0387890718 ISBN-13(EAN): 9780387890715
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Retinoblastoma is the most common cancer of the eye in children. Although it is a rare neoplasm, there are many features that make this malignancy unique. Nationally, the incidence is approximately 4 million children per year. 90 per cent of these cases occur in children under 5 and more than 90 per cent will be cured.

Автор: Jasmine H. Francis; David H. Abramson
Название: Recent Advances in Retinoblastoma Treatment
ISBN: 3319194666 ISBN-13(EAN): 9783319194660
Издательство: Springer
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Цена: 16769.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: It addresses all the essential aspects of retinoblastoma and its management, including: its molecular biology and genetics, management by focal treatment, intraarterial and intravitreal chemotherapy, electroretinogram monitoring of treatment, pharmacokinetic studies, high-risk features, treatment of metastatic disease, and long-term follow-up.