The Retinoblastoma Protein, Pedro G. Santiago-Cardona

Автор: Carlos Rodriguez-Galindo (Ed.)
Название: Biology and treatment of retinoblastoma
ISBN: 0387890718 ISBN-13(EAN): 9780387890715
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Retinoblastoma is the most common cancer of the eye in children. Although it is a rare neoplasm, there are many features that make this malignancy unique. Nationally, the incidence is approximately 4 million children per year. 90 per cent of these cases occur in children under 5 and more than 90 per cent will be cured.

Автор: Matthew W. Wilson
Название: Retinoblastoma
ISBN: 1489977538 ISBN-13(EAN): 9781489977533
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Although rare, retinoblastoma has been at the fore- fortunate; while in the developed world eye preser- front of cancer research and treatment for the last tion has become a priority, developing countries c- three decades. The two-hit hypothesis of oncogenesis tinue to face delays in diagnosis, poor access to care, proposed by Alfred Knudson provided the conceptual and suboptimal treatment – the problem in the less framework for tumor suppressor gene research and developed world is cure. led to the discovery of the retinoblastoma pathway as In this book, we have invited a team of experts to a key element in cancer development. More recently, address all those important aspects of retinoblastoma the treatment of children with retinoblastoma has also research and therapy - from biology to epidemiology provided a model for modern approach to the can- to treatment. We hope that in subsequent editions we cer patient; state of the art retinoblastoma treatment will be able to continue to provide updates on such can only be conceived in the context of the multidis- exciting subjects.

Автор: Jasmine H. Francis; David H. Abramson
Название: Recent Advances in Retinoblastoma Treatment
ISBN: 3319194666 ISBN-13(EAN): 9783319194660
Издательство: Springer
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Цена: 16769.00 р.
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Описание: It addresses all the essential aspects of retinoblastoma and its management, including: its molecular biology and genetics, management by focal treatment, intraarterial and intravitreal chemotherapy, electroretinogram monitoring of treatment, pharmacokinetic studies, high-risk features, treatment of metastatic disease, and long-term follow-up.