Автор: Birkett Название: Pharmacokinetics made Easy ISBN: 0074710729 ISBN-13(EAN): 9780074710722 Издательство: McGraw-Hill Цена: 2057.00 р. Наличие на складе: Невозможна поставка. Описание: This volume features a collection of published articles that appeared in "Australian Prescriber" on the subject of pharacokinetics. It aims to make the subject more accessible to its non-specialist audience, adopting a physiological approach with direct application of the concepts to practical issues related to drug therapy. This revised edition includes a new chapter on population pharmacokinetics, to reflect developments in the field. It also features self-assessment questions in each chapter and equations to explain physiological factors underlying important pharmacokinetics processes.
Автор: Bauer, Larry A. Название: Applied clinical pharmacokinetics ISBN: 0071476288 ISBN-13(EAN): 9780071476287 Издательство: McGraw-Hill Рейтинг: Цена: 7720.00 р. Наличие на складе: Поставка под заказ.
Описание: Features coverage of drug dosing and monitoring. This book focuses on the standardized techniques and approaches to patient-specific dosing. It also contains sections on dosing strategies in the chapters and a chapter on sirolimus.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.
Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. www.springeronline.com
Автор: Rescigno Aldo Название: Foundations of Pharmacokinetics ISBN: 0306477041 ISBN-13(EAN): 9780306477041 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is divided into two parts; in the first part the principles and the methods of pharmacokinetics are described in detail, while in the second the main pharmacokinetic parameters are described, giving for each of them the definition, the principal properties, and the methods of determination. An appendix contains the important mathematical instruments used in the main part of the book, namely the operational calculus and the convolution integral. In the second part there is a careful distinction among pharmacokinetic parameters, i.e., parameters that represent a true pharmacokinetic property, model parameters, i.e., parameters that represent a property of a specific model, and incidental parameters, i.e., parameters that represent only the result of a particular experiment. Special care is taken to distinguish between the definition of a parameter, and the properties that derive from that definition; a considerable emphasis is also given to the fact that each method for the determination of a parameter is dependent on the specific model it is based on.
Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton ( Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics ISBN: 0387756124 ISBN-13(EAN): 9780387756127 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.
Автор: Bauer Название: Handbook of clinical pharmacokinetics ISBN: 007142542X ISBN-13(EAN): 9780071425421 Издательство: McGraw-Hill Рейтинг: Цена: 6347.00 р. Наличие на складе: Поставка под заказ.
Описание: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. It also features calculation methods, algorithms for choosing the best calculation method, and case studies.
Автор: Shargel Название: Applied Biopharmaceutics & Pharmacokinetics ISBN: 0071240055 ISBN-13(EAN): 9780071240055 Издательство: McGraw-Hill Цена: 4288.00 р. Наличие на складе: Поставка под заказ.
Описание: The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.
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