Описание: This book reviews diversity-oriented synthesis (DOS), a leading and dynamic area in organic chemistry and drug discovery. It first covers key chemical methods for the generation of small molecules according to DOS principles as well as important classes of molecules generated through DOS approaches.
Автор: Thomas G. Davies; Marko Hyv?nen Название: Fragment-Based Drug Discovery and X-Ray Crystallography ISBN: 3642446353 ISBN-13(EAN): 9783642446351 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson
Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle
Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard
Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford
Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber
Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyv nen
Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold
Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan
Автор: Semizarov, Dimitri Blomme, Eric Название: Genomics in drug discovery and development ISBN: 0470096047 ISBN-13(EAN): 9780470096048 Издательство: Wiley Рейтинг: Цена: 22168.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure.
Автор: Qing Yan Название: Pharmacogenomics in Drug Discovery and Development ISBN: 1617378259 ISBN-13(EAN): 9781617378256 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume explores cutting-edge technologies used to pursue systems-based pharmacogenomics. Extensive chapters follow on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases.
Автор: Gad Название: Drug Discovery HB.2005 ISBN: 0471213845 ISBN-13(EAN): 9780471213840 Издательство: Wiley Рейтинг: Цена: 30888.00 р. Наличие на складе: Поставка под заказ.
Описание: The Drug Discovery Handbook gives the professional a comprehensive, practical guide for professionals the latest techniques and methods in drug discovery, including genomics, involved in drug discovery. This practical guide will present an explanation of proteomics, high throughput screening, and systems biology. This resource summarizes how these techniques and methods are used to discover new central nervous system agents, antiviral agents, respiratory drugs, oncology drugs, etc. Individual chapters detail specific approaches to drug discovery, including problems that are encountered, solutions to these problems, and limitations of various methods and techniques.
Автор: Mark von Itzstein Название: Influenza Virus Sialidase - A Drug Discovery Target ISBN: 3034807791 ISBN-13(EAN): 9783034807791 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Following an overview of the influenza virus, the haemagglutinin, the interactions with the cell receptors and the enzymology of virus sialidase, recent results in drug design are presented.
Описание: Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant and most challenging areas of drug discovery.
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