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Gene Regulation by Steroid Hormones IV, Arun K. Roy; James H. Clark


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Автор: Arun K. Roy; James H. Clark
Название:  Gene Regulation by Steroid Hormones IV
ISBN: 9781461281979
Издательство: Springer
Классификация:


ISBN-10: 1461281970
Обложка/Формат: Soft cover
Страницы: 239
Вес: 0.39 кг.
Дата издания: 06.10.2011
Язык: English
Издание: Softcover reprint of
Иллюстрации: Biography
Размер: 234 x 156 x 14
Читательская аудитория: Professional & vocational
Основная тема: Cell Biology
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The first Meadowbrook Symposium was held in 1978 and during the intervening ten years our knowledge concerning how steroid hormones function at the level of gene expression has advanced by leaps and bounds.


Gene Regulation by Steroid Hormones III

Автор: Arun K. Roy; James H. Clark
Название: Gene Regulation by Steroid Hormones III
ISBN: 1461291143 ISBN-13(EAN): 9781461291145
Издательство: Springer
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Цена: 19591.00 р.
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Описание: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Gene Regulation by Steroid Hormones II

Автор: A.K. Roy; J.H. Clark
Название: Gene Regulation by Steroid Hormones II
ISBN: 1461254841 ISBN-13(EAN): 9781461254843
Издательство: Springer
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Цена: 19591.00 р.
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Описание: Receptors and Gene Expression It is now more than three years since the last Meadow Brook Conference on Hormones, and a great deal has happened in the meantime. Steroid hormones have been localized on target genes providing the long awaited evidence for the concept of a direct effect of the steroid-receptor complex on gene regulation.

Steroid Hormones and Cell Cycle Regulation

Автор: Kerry L. Burnstein
Название: Steroid Hormones and Cell Cycle Regulation
ISBN: 1461353270 ISBN-13(EAN): 9781461353270
Издательство: Springer
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Цена: 13974.00 р.
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Описание: From the tissue culture dish to genetically modified mice, this volume explores the long recognized role of steroid hormones in regulating cell proliferation and differentiation.

Steroid Hormones and the T-Cell Cytokine Profile

Автор: G.A.W. Rook; S. Lightman
Название: Steroid Hormones and the T-Cell Cytokine Profile
ISBN: 1447112385 ISBN-13(EAN): 9781447112389
Издательство: Springer
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Цена: 15672.00 р.
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Описание: The fact that certain adrenal steroid hormones are immunosuppressive and anti-inflammatory has been known for many years, and is routinely exploited by physicians. These effects are attributable to glucocorticoid steroids such as cortisol. Pharmacological doses of glucocorticoids inhibit most or all T cell types. However we now know that the effect of exposure to raised physiological levels is mainly to drive developing lymphocyte responses towards a Th2 cytokine profile (interleukin-4 secreting) while suppressing the development ofThi (gamma interferon- secreting) lymphocytes. Only recently have two further regulatory mechanisms become appar- ent. First, these effects of cortisol are balanced by pro-inflammatory and ThI-enhancing effects of another adrenal steroid, dehydroepiandro- sterone sulfate (DHEAS). Second, the activity of cortisol is directly modulated by enzymes in the target organs and lymphoid tissues that convert it into inactive cortisone. This new information leads to the possibility that immunoregulatory steroids could be used by physicians in novel ways. We can envisage steroid combinations that exploit the anti-inflammatory effects of corti- sol, while the Thi-suppressing and Th2-promoting properties of these hormones are opposed by derivatives of DHEAS. Such therapies are already proving effective in animal models of infection, and could revol- utionize treatment of Th2-mediated diseases such as asthma, where the anti-inflammatory effects of cortisol are desirable but the effects on T lymphocyte differentiation are not.

Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones

Автор: Jack R. Jr. Lancaster; J.F. Parkinson
Название: Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones
ISBN: 3662035057 ISBN-13(EAN): 9783662035054
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The discovery of mammalian nitric oxide (NO-) synthesis from I-ar- ginine has led to profound increases in our understanding of basic physiological and pathophysiological processes. This understanding has been achieved by major advances in several areas. Three major ni- tric oxide synthase (NOS) isoforms have been identified at the protein and gene level and their specific tissue localization has been linked to processes subject to regulation by NO-. The molecular basis for the di- verse effects of NO- on cell function has been shown to derive from its chemical reactivity with oxygen-containing species and both heme and non-heme iron-dependent enzymes. The potential regulation of heme- dependent enzymes such as cytochromes P450, guanylate cyclase, cy- clooxygenase, and mitochondrial cytochrome oxidase continues to emerge as a key area in NO- research. In addition, it has become clear that the expression of NOS isoforms and NO- release from cells is subject to regulation by sexual steroids and that, in tum, NO- has the potential to regulate steroid biosynthesis via inhibition of cytochromes P450 involved in steroidogenesis. These recent observations on interactions between the NO-/NOS and cytochrome P450/sexual steroid pathways have important implica- tions for understanding fundamental mechanisms involved in endocri- nological processes. They are also likely to lead to novel insights and novel therapeutic approaches for the management of pathophysiologi- cal conditions associated with alterations in sexual steroid hormones.

Regulation of Gene Expression by Hormones

Автор: Kenneth McKerns
Название: Regulation of Gene Expression by Hormones
ISBN: 1468444204 ISBN-13(EAN): 9781468444209
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Among our interests are global resource management, human reproduction, hormonal regulation of normal and cancer cells, study of aging and degenerative diseases, brain peptides, peptide neurotransmitter compounds, mechanism of action of hormones, peptide hormone synthesis, and recombinant DNA techniques.

Hormones in Ageing and Longevity

Автор: Suresh Rattan; Ramesh Sharma
Название: Hormones in Ageing and Longevity
ISBN: 3319630008 ISBN-13(EAN): 9783319630007
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This multi-chapter book focuses on one of the hottest topics in ageing research - the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity.

Hormones: A Very Short Introduction

Автор: Luck Martin
Название: Hormones: A Very Short Introduction
ISBN: 0199672873 ISBN-13(EAN): 9780199672875
Издательство: Oxford Education
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Цена: от 1138.00 р.
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Описание: Hormones are vital to the workings of the body, and while many people are aware of what hormones do, few have an appreciation of the nature and importance of the endocrine system. In this Very Short Introduction, Martin Luck explains what hormones are, what they do, where they come from, and how they work.


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