Gene Regulation by Steroid Hormones III, Arun K. Roy; James H. Clark
Автор: A.K. Roy; J.H. Clark Название: Gene Regulation by Steroid Hormones II ISBN: 1461254841 ISBN-13(EAN): 9781461254843 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Receptors and Gene Expression It is now more than three years since the last Meadow Brook Conference on Hormones, and a great deal has happened in the meantime. Steroid hormones have been localized on target genes providing the long awaited evidence for the concept of a direct effect of the steroid-receptor complex on gene regulation.
Автор: Luck Martin Название: Hormones: A Very Short Introduction ISBN: 0199672873 ISBN-13(EAN): 9780199672875 Издательство: Oxford Education Рейтинг: Цена: от 1138.00 р. Наличие на складе: Есть
Описание: Hormones are vital to the workings of the body, and while many people are aware of what hormones do, few have an appreciation of the nature and importance of the endocrine system. In this Very Short Introduction, Martin Luck explains what hormones are, what they do, where they come from, and how they work.
Автор: Arun K. Roy; James H. Clark Название: Gene Regulation by Steroid Hormones IV ISBN: 1461281970 ISBN-13(EAN): 9781461281979 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The first Meadowbrook Symposium was held in 1978 and during the intervening ten years our knowledge concerning how steroid hormones function at the level of gene expression has advanced by leaps and bounds.
Автор: G.A.W. Rook; S. Lightman Название: Steroid Hormones and the T-Cell Cytokine Profile ISBN: 1447112385 ISBN-13(EAN): 9781447112389 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The fact that certain adrenal steroid hormones are immunosuppressive and anti-inflammatory has been known for many years, and is routinely exploited by physicians. These effects are attributable to glucocorticoid steroids such as cortisol. Pharmacological doses of glucocorticoids inhibit most or all T cell types. However we now know that the effect of exposure to raised physiological levels is mainly to drive developing lymphocyte responses towards a Th2 cytokine profile (interleukin-4 secreting) while suppressing the development ofThi (gamma interferon- secreting) lymphocytes. Only recently have two further regulatory mechanisms become appar- ent. First, these effects of cortisol are balanced by pro-inflammatory and ThI-enhancing effects of another adrenal steroid, dehydroepiandro- sterone sulfate (DHEAS). Second, the activity of cortisol is directly modulated by enzymes in the target organs and lymphoid tissues that convert it into inactive cortisone. This new information leads to the possibility that immunoregulatory steroids could be used by physicians in novel ways. We can envisage steroid combinations that exploit the anti-inflammatory effects of corti- sol, while the Thi-suppressing and Th2-promoting properties of these hormones are opposed by derivatives of DHEAS. Such therapies are already proving effective in animal models of infection, and could revol- utionize treatment of Th2-mediated diseases such as asthma, where the anti-inflammatory effects of cortisol are desirable but the effects on T lymphocyte differentiation are not.
Описание: The neuroendocrine control of reproduction and development of inver- tebrates has a long tradition as an important area of research in France. The reader of this volume is certainly familiar with the significant con- tributions to this field made by such outstanding scientific personalities as J ean-J acques Bounhiol, Jean Panouse, Bernard Possompes, Pierre and Line Joly, Helene Charniaux-Cotton, Maurice Durchon, Manfred Gabe, Guy Echalier, Marie Raabe, and others. It is therefore not surprising that the Centre National de la Recherche Scientifique (CNRS) sponsored, in 1975 and 1983, two major inter- national meetings devoted to this subject. The organizers of the 1975 meeting, which was held in Lille, decided to concentrate on the bio- synthesis, metabolism, and mode of action of the invertebrate hor- mones. To some extent, Professors Durchon and J oly wanted to convey the message that they felt that the period of classical invertebrate endo- crinology had come to an end and that traditional approaches were be- ing replaced by biochemical analyses. How right they were is illustrated by the present volume. Today biochemistry, molecular biology, and analytical chemistry are tools of the invertebrate endocrinologist, who now starts his morning work by homogenizing his worm, mollusc, insect . . . and by extracting DNA, steroids, or peptides.
Автор: A.R. McCaffery; I.D. Wilson Название: Chromatography and Isolation of Insect Hormones and Pheromones ISBN: 1468480642 ISBN-13(EAN): 9781468480641 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the First International Symposium jointly organized by the Chromatographic Society and the Royal Entomological Society of London, held in Reading, UK, March 21-23, 1989.
Автор: Seckl Название: Hormones, Intrauterine Health and Programming ISBN: 3319025902 ISBN-13(EAN): 9783319025902 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The authors address in particular the role of hormones and their links with other maternal environmental mediators in developmental programming.
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