Автор: Cornelis Murre Название: Epigenetic Regulation of Lymphocyte Development ISBN: 3642447678 ISBN-13(EAN): 9783642447679 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.
Автор: Rast Название: Immune Receptors ISBN: 1617791385 ISBN-13(EAN): 9781617791383 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Immunology has made significant progress in the past decade, driven forward by rapidly advancing technology and a renewed interest in the vast realm of innate immunity. The receptors that mediate these functions are at the front lines of both protective and regulative roles of the immune system. In Immune Receptors: Methods and Protocols, expert researchers present a variety of experimental approaches to the characterization of immune receptors and the cell biology that mediates their functions. These include imaging techniques that aim to understand receptor localization and trafficking, techniques to measure receptor-ligand interactions, strategies to identify novel ligands and methods to analyze downstream receptor signaling, as well as strategies for genomic and proteomic characterization of receptor repertoires. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immune Receptors: Methods and Protocols offers technical descriptions and protocols that will be useful both to investigators who are interested in carrying out these procedures and to those who seek a deeper understanding of the bench science that lies behind the immunology literature.
Автор: Sudhir Gupta; Frederick W. Alt; Max D. Cooper; Fri Название: Mechanisms of Lymphocyte Activation and Immune Regulation XI ISBN: 1441942831 ISBN-13(EAN): 9781441942838 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires.
Автор: Gary B. Huffnagle; Mairi Noverr Название: GI Microbiota and Regulation of the Immune System ISBN: 1489988165 ISBN-13(EAN): 9781489988164 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers current trends in the investigation of GI microbiota. It examines the relationship between the microbiota and the immune system from a variety of angles.
Автор: Cornelis Murre Название: Long Range Regulation of V(D)J Recombination,128 ISBN: 0128032960 ISBN-13(EAN): 9780128032961 Издательство: Elsevier Science Рейтинг: Цена: 22570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens
As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.
Описание: This book explores the major cytokines, such as IL-1 and IFN-?, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.
Автор: Michael Sch?fer; Christoph Stein Название: Mind over Matter - Regulation of Peripheral Inflammation by the CNS ISBN: 3034894163 ISBN-13(EAN): 9783034894166 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume deals with the various interactions between the central nervous system and the immune system in inflammatory conditions. The emphasis is on the origin of pain and stress and their treatment. The book is divided into four parts: central nervous system and inflammation, stress and inflammation, sympathetic nervous system, and peripheral nervous system and inflammation.
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