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Extrasynaptic GABAA Receptors, Adam C. Errington; Giuseppe Di Giovanni; Vincenzo


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Автор: Adam C. Errington; Giuseppe Di Giovanni; Vincenzo
Название:  Extrasynaptic GABAA Receptors
ISBN: 9781493914258
Издательство: Springer
Классификация:



ISBN-10: 1493914251
Обложка/Формат: Hardcover
Страницы: 295
Вес: 0.63 кг.
Дата издания: 23.09.2014
Серия: The Receptors
Язык: English
Издание: 2014 ed.
Иллюстрации: 5 tables, black and white; 18 illustrations, color; 16 illustrations, black and white; ix, 295 p. 34 illus., 18 illus. in color.
Размер: 234 x 156 x 19
Читательская аудитория: Professional & vocational
Основная тема: Neurosciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed “tonic” inhibition, has been described. Whereas synaptic GABAA receptors underlie classical “phasic” GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.
Дополнительное описание: A brief introduction to extrasynaptic GABAA receptors and ‘tonic’ GABAA receptor mediated inhibition in physiology and disease.- Extrasynaptic GABAA receptors: subunit composition, distribution, and regulation.- Biophysical properties of recombinant 2- AN



Prostacyclin and Its Receptors

Автор: Helen Wise; Robert L. Jones
Название: Prostacyclin and Its Receptors
ISBN: 1475781822 ISBN-13(EAN): 9781475781823
Издательство: Springer
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Цена: 16979.00 р.
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Описание: In addition to its well known anti-platelet and hypotensive properties, prostacyclin activates neuronal receptors in the central, enteric and sensory nervous systems. This volume discusses the properties of prostacyclin receptors in the cardiovascular and nervous systems, as well as in cells involved in inflammatory reactions.

Receptors in the Developing Nervous System

Автор: Zagon; McLaughlin
Название: Receptors in the Developing Nervous System
ISBN: 9401046727 ISBN-13(EAN): 9789401046725
Издательство: Springer
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Цена: 15672.00 р.
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Описание: Receptors for cell hormones, growth factors, Fourth, alterations in the development of and neurotransmitters are involved in the neural receptors may have profound implica- control and modulation of an enormous array tions for the structure and function of the of biological processes.

Insulin, Insulin-like Growth Factors, and Their Receptors in the Central Nervous System

Автор: Mohan Raizada
Название: Insulin, Insulin-like Growth Factors, and Their Receptors in the Central Nervous System
ISBN: 1468453823 ISBN-13(EAN): 9781468453829
Издательство: Springer
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Цена: 15672.00 р.
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Описание: Traditionally, intercellular communication and the regulation of biological functions of the body have been considered the role of two major and distinct systems: the nervous system and the endocrine system.

Toll-like Receptors: Roles in Infection and Neuropathology

Автор: Tammy Kielian
Название: Toll-like Receptors: Roles in Infection and Neuropathology
ISBN: 3642269117 ISBN-13(EAN): 9783642269110
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This book highlights traditional roles for TLRs in infectious diseases of the CNS. It also discusses recently emerging roles for TLRs in non-infectious neurodegenerative diseases and the challenges faced in these models with identifying endogenous ligands.

Cell Surface Receptors

Автор: Lee E. Limbird
Название: Cell Surface Receptors
ISBN: 1475718845 ISBN-13(EAN): 9781475718843
Издательство: Springer
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Цена: 14365.00 р.
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A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics

Автор: Borea
Название: A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics
ISBN: 904813143X ISBN-13(EAN): 9789048131433
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This book covers the current state of knowledge of the adenosine A3 receptor. Coverage includes data from studies of theoretical, molecular, and cellular pharmacology, signal transduction, integrative physiology, new drug discoveries and clinical applications.

Diversity and Functions of GABA Receptors: A Tribute to Hanns Moh

Автор: Uwe Rudolph
Название: Diversity and Functions of GABA Receptors: A Tribute to Hanns Moh
ISBN: 012802660X ISBN-13(EAN): 9780128026601
Издательство: Elsevier Science
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Цена: 29812.00 р.
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Описание:

This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.

Histamine Receptors

Автор: Blandina
Название: Histamine Receptors
ISBN: 3319403060 ISBN-13(EAN): 9783319403069
Издательство: Springer
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Цена: 23508.00 р.
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Описание: A comprehensive and detailed overview of the current state of preclinical research on histamine and histamine receptors. Part of the book focuses on novel approaches to the study of histamine receptors such as polymorphism, genetic linkage, and computational analysis, and on the use of new histaminergic ligands in diseases such as asthma and dermatitis. Several chapters will be devoted to the role of histamine in the control of homeostatic and behavioral responses such as the sleep-wake cycle, regulation of the blood brain barrier, food intake, alertness, itch, and memory formation and consolidation.

Receptors

Автор: Stanford
Название: Receptors
ISBN: 0199638829 ISBN-13(EAN): 9780199638826
Издательство: Oxford Academ
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Цена: 13464.00 р.
Наличие на складе: Поставка под заказ.

Описание: A comprehesive review of methods that can be used for studying cellular receptors, examining how each technique can be used on different receptor types. It offers comprehensive coverage of a wide range of techniques, exploring up-to-date developments rather than established methods.


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