Автор: Margot M. Ip; Bonnie B. Asch Название: Methods in Mammary Gland Biology and Breast Cancer Research ISBN: 1461369274 ISBN-13(EAN): 9781461369271 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This influx, which has been due primarily to the tireless efforts of breast cancer activists to gamer addi tional money from various federal and state sources, has led to a rapid expansion of research efforts by attracting numerous new investigators into the field.
Автор: Yu Название: Cancer Stem Cells ISBN: 1588299384 ISBN-13(EAN): 9781588299383 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Поставка под заказ.
Описание: Compiles cancer stem cell research techniques and protocols to promote healthy competition, discourse, and collaboration in this field. This title covers topics such as identification and isolation of cancer stem cells, animal models of cancer stem cells, methylation profiling, and the contribution of niche in the regulation of cancer stem cells.
Автор: Goldenberg Название: Resident Stem Cells and Regenerative Therapy, ISBN: 0124160123 ISBN-13(EAN): 9780124160125 Издательство: Elsevier Science Рейтинг: Цена: 21054.00 р. Наличие на складе: Поставка под заказ.
Описание: Stem cells have greatly impacted the scientific and lay communities, providing advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, cystic fibrosis, cirrhosis, and osteoporosis. This title presents the important factors to be considered when considering resident stem cells in regenerative therapies.
Автор: Sadhan Majumder (Ed.) Название: Stem Cells and Cancer ISBN: 0387896104 ISBN-13(EAN): 9780387896106 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Поставка под заказ.
Описание: Cancer is a primary cause of human mortality worldwide. This book intends to impart information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies.
Автор: Zhang Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 1607617684 ISBN-13(EAN): 9781607617686 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.
Автор: Mathews Название: DNA Repair of Cancer Stem Cells ISBN: 9400745893 ISBN-13(EAN): 9789400745896 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA repair mechanism(s) and their role in the maintenance and regulation of both normal and cancer stem cells. Our book represents a comprehensive investigation into the highly effective DNA repair mechanisms of CSCs and what we need to understand in order to develop more advanced therapies to eradicate them from patients. Currently, there are no other published works entirely on DNA repair and Cancer Stem Cells. In addition, our book provides a comprehensive overview of CSC isolation and characterization from a variety of solid tumor types.
Автор: Otmar D. Wiestler; Bernhard Haendler; D. Mumberg Название: Cancer Stem Cells ISBN: 3540708529 ISBN-13(EAN): 9783540708520 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer stem cells have originally been identified in leukemia and later in several solid tumor types. They have very different properties from the bulk of the tumor as they divide much more slowly and have very efficient drug resistance mechanisms. This book looks at various developments in the field of cancer stem cells.
Автор: Quigley Muireann Название: Stem Cells: New Frontiers in Science & Ethics ISBN: 9814374245 ISBN-13(EAN): 9789814374248 Издательство: World Scientific Publishing Рейтинг: Цена: 15048.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Deals with various aspects of the stem cell debate, from the ethical challenges of conducting stem cell research to those of the clinical application of stem cell technology. This title brings fresh perspectives on the permissibility of using embryos in stem cell research.
Автор: Justin Ainscough; Shinya Yamanaka; Takashi Tada Название: Nuclear Reprogramming and Stem Cells ISBN: 162703904X ISBN-13(EAN): 9781627039048 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mechanisms that drive disease aetiology the research is realistically opening the doors for development of targeted and personalized therapeutic applications that many considered, until recently, to be nothing more that a far fetched dream. This volume provides a timely glimpse into the methods that have been developed to instigate, and the mechanisms that have been identified to drive, the process of nuclear reprogramming, chronicling how the field has developed over the last 50-60 years. Since the early 1950s a small number of notable experiments have provided significant impetus to the field, primarily the demonstration of reprogramming ability, first by the complex cytoplasmic milieu that constitutes the amphibian egg, then that of the mammalian egg, and finally that of the mammalian embryonic stem cell. Most recently, the demonstration that a limited pool of defined molecules is capable of reprogramming a multitude of cell types has provided massive impetus and facilitated transition towards realistic therapeutic application. We have therefore reproduced some of the key articles that elegantly document these dramatic stages of development of the field in an inclusive appendix to the book, for the benefit of readers keen to investigate the history of how the field of stem cell biology has evolved. Owing to the ever broadening nature of this field, and the incredible rate at which it is evolving, the main content of this volume focuses on areas that have shown significant movement in recent years, are most likely to translate into personalized therapeutic application, and thus provide greatest potential for significant impact on human health in the not too distant future. We recognize that research into many other disease states and cell types are all equally worthy of discussion. We would therefore like to acknowledge those researchers involved whose work we have not been able to include in this volume. Nuclear Reprogramming and Stem Cells will serve as a valuable resource for all researchers in the field of stem cell biology, including those just setting out on their career path as well as those already established in the field.
Автор: Hayat Название: Stem Cells and Cancer Stem Cells, Volume 11 ISBN: 9400773285 ISBN-13(EAN): 9789400773288 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: multipotent stem cells, which can generate all cells in a particular lineage and unipotent stem cells, which can give rise to only one cell type.
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